Pulmoner hamartomlarda tanısal zorluklar: vaka serisi

Abstract

Pulmoner hamartomlar, benign olmalarına rağmen maligniteyi taklit eden görüntüleme bulguları nedeniyle tanısal zorluklar yaratabilir. Bu çalışmada, malignite şüphesiyle cerrahiye alınan üç hamartom vakası ve cerrahi sonrası tipik karsinoid tümör tanısı alan bir vaka sunularak, pulmoner hamartomların tanı ve tedavisinde karşılaşılan güçlükler tartışılmıştır. Çalışma, malignite şüphesi nedeniyle cerrahiye yönlendirilen dört vakanın retrospektif olarak değerlendirilmesiyle gerçekleştirilmiştir. Vakalar radyolojik, cerrahi ve patolojik bulgular açısından incelenmiştir. Üç vaka, benign özellikler göstermesine rağmen malignite şüphesiyle opere edilmiş ve patoloji sonucunda hamartom olarak raporlanmıştır. Bir vaka ise, radyolojik olarak benign özellikler taşımasına rağmen cerrahi sonrası tipik karsinoid tümör olarak tanımlanmıştır. Pulmoner hamartomlar, benign görünümlerine rağmen maligniteyi taklit edebilir ve nadiren malign transformasyon gösterebilir. Bu nedenle, multidisipliner bir yaklaşım, cerrahi rezeksiyon ve histopatolojik inceleme, kesin tanı için vazgeçilmezdir. Genetik analizlerin eklenmesi, tanı sürecini daha kapsamlı hale getirebilir.

Keywords

• Pulmoner hamartom
• malignite
• cerrahi rezeksiyon
• histopatoloji
• multidisipliner yaklaşım

Diagnostic challenges in pulmonary hamartomas: a case series

Abstract

Pulmonary hamartoma, despite its benign nature, can pose diagnostic challenges due to imaging findings that mimic malignancy. This case series discusses the diagnostic and therapeutic difficulties in pulmonary hamartomas. These three cases that are presented here were surgically managed under suspicion of malignancy and one case was diagnosed as a typical carcinoid tumor postoperatively. The study retrospectively evaluated four cases referred for surgery due to suspected malignancy. The cases were analyzed in terms of radiological, surgical, and pathological findings. Three cases showed benign features but were operated on due to suspected malignancy and history of malignancy, and were confirmed as hamartomas on pathology. One case, despite radiological features suggesting benignity, was identified as a typical carcinoid tumor postoperatively. Pulmonary hamartomas, despite their benign nature, can mimic malignancy and rarely undergo malignant transformation. Therefore, a multidisciplinary approach, surgical resection, and histopathological examination are essential for accurate diagnosis. Incorporating genetic analyses could enhance the diagnostic process further.

Keywords

• Pulmonary hamartoma
• malignancy
• surgical resection
• histopathology
• multidisciplinary approach

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