A rare case of ovarian pathology: diffuse large B cell lymphoma of over
Abstract
Primary ovarian non-Hodgkin lymphoma is a challenging diagnosis due to its rarity, often leading to delayed treatment, wrong diagnosis, and inappropriate therapy. The patient in this case presentation presented with abdominal pain as the initial symptom. Subsequent abdominal computed tomography revealed a bilateral heterogeneous ovarian mass measuring approximately 6x10x10 cm on the left side and 14x10x7 cm on the right side. An intestinal mass lesion was observed in the ileal ans, causing diffuse wall thickening of ~2 cm at its widest point and focal lumen widening in an ~11 cm segment (lymphoma?). A transvaginal ultrasound was also performed, revealing two cystic masses, one measuring 10 cm and the other 12 cm, with dense and heterogeneous contents filling the uterine cavity and pelvis. Subsequently, a total abdominal hysterectomy, bilateral salpingo-oophorectomy, bilateral pelvic lymph node dissection, and small bowel resection and anastomosis were performed.
Keywords
References
- Takeuchi T, Yamaguchi M, Kobayashi K, et al. MYD88, CD79B, and CARD11 gene mutations in CD5-positive diffuse large B-cell lymphoma. Cancer. 2017;123(7):1166-1173. doi:10.1002/cncr.30404
- AlShemmari SH, Ameen RM, Sajnani KP. Extranodal lymphoma: a comparative study. Hematology. 2008;13(3):163-169. doi:10.1179/102453308X316149
- Yun J, Kim SJ, Won JH, et al. Clinical features and prognostic relevance of ovarian involvement in non-Hodgkin's lymphoma: A Consortium for Improving Survival of Lymphoma (CISL) report. Leuk Res. 2010;34(9):1175-1179. doi:10.1016/j.leukres.2010.02.010
- Kumar N, Kumar R, Bera A, Srinivasan R, Sharma SC. Primary ovarian lymphoma: a case report and review of literature. J Obstet Gynaecol India. 2014;64(1):65-67. doi:10.1007/s13224-012-0200-6
- Monterroso V, Jaffe ES, Merino MJ, Medeiros LJ. Malignant lymphomas involving the ovary. A clinicopathologic analysis of 39 cases. Am J Surg Pathol. 1993;17(2):154-170. doi:10.1097/00000478-199302000-00007
- Dimopoulos MA, Daliani D, Pugh W, Gershenson D, Cabanillas F, Sarris AH. Primary ovarian non-Hodgkin's lymphoma: outcome after treatment with combination chemotherapy. Gynecol Oncol. 1997;64(3):446-450. doi:10.1006/gyno.1996.4583,
- Gök S, Alataş E, Düzcan E. Overin nadir tümörü: sklerozan stromal tümör. Pam Tıp Derg. 2020;13(2):449-452. doi:10.31362/patd.670426
- Onyiuke I, Kirby AB, McCarthy S. Primary gynecologic lymphoma: imaging findings. AJR Am J Roentgenol. 2013;201(4):W648-W655. doi:10.2214/AJR.12.8907
Details
Primary Language
English
Subjects
Obstetrics and Gynaecology
Journal Section
Case Report
Authors
Soner Gök
0000-0001-8940-1879
Türkiye
Sinan Baldağ
*
0009-0007-8338-9195
Türkiye
Erkan Alataş
0000-0001-6423-5106
Türkiye
Nilay Şen Türk
0000-0002-8294-558X
Türkiye
Publication Date
July 10, 2026
Submission Date
December 19, 2025
Acceptance Date
March 3, 2026
Published in Issue
Year 2026 Volume: 19 Number: 3
