Heterotopic pregnancy, which is rare after ovulation induction with clomiphene citrate and timed intercourse.

Abstract

The condition of the coexistence of intrauterine and extrauterine pregnancies is called as heterotopic pregnancy. The incidence is 1/30000 with natural conception and increases up to 1/100 with assisted reproductive techniques (ART). Clomiphene Citrate, a drug for ovulation induction, is used as a treatment approach for the patients with oligo-ovulation and subfertility with normal estrogen levels. This treatment may lead to the development of more than one follicle, ovarian hyperstimulation and multiple gestations. Increased estrogen level after ovulation induction disrupts tubal transport and increases ectopic pregnancy risk. In our case, we aimed to emphasize the difficulties of diagnosing heterotopic pregnancy, which is rare after ovulation induction with clomiphene citrate and timed intercourse, current diagnosis and treatment methods, as well as the importance of clinical and ultrasonographic evaluation of pelvic and adnexial structures of all terminated or ongoing first trimester pregnancies.

İngilizce Kısa Başlık: Clomiphene citrate induction and heterotopic pregnancy

Keywords

• Ovulation induction,Clomiphene Citrate,Heterotopic pregnancy

Klomifen sitrat ile ovulasyon indüksiyonu ve doğal ilişki sonrası ender görülen heterotopik gebelik

Abstract

İntrauterin ve ekstrauterin gebeliğin aynı anda birlikte bulunmasına heterotopik gebelik adı verilir. İnsidansı doğal ilişkiyle 1/30000 iken yardımcı üreme teknikleri sonrasında 1/100 e kadar ulaşmaktadır. Ovulasyon indüksiyonu yöntemlerinden Klomifen Sitrat normal östrojenize oligo-ovulasyonlu ve subfertillerde seçilen bir tedavi yöntemidir. Bu tedavi birden fazla folikül gelişmesine, ovaryan hiperstimülasyona ve çoğul gebeliğe neden olmaktadır. Ovulasyon indüksiyonu sonrası artan östrojen seviyesi tubal transportu bozmakta ve ektopik gebelik riskini arttırmaktadır. Biz olgumuzda klomifen sitrat indüksiyonu ve doğal ilişki sonrası ender görülen heterotopik gebeliğin teşhisinin zorluklarını, güncel tanı ve tedavi yöntemlerini, sonlanan veya devam eden tüm ilk trimester gebeliklerde pelvik ve adneksiyel yapılarının klinik ve ultrasonografik olarak değerlendirilmesinin önemini vurgulamayı amaçladık.

Türkçe Kısa Başlık: Klomifen Sitrat indüksiyonu ve heterotopik gebelik

Keywords

• Ovulasyon indüksiyonu,Klomifen Sitrat,Heterotopik gebelik

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