Osteoartritli hastalarda retina kalınlığının değerlendirilmesi

Year 2019, , 123 - 126, 18.01.2019

Nusret Ök , Gökhan Pekel

https://doi.org/10.31362/patd.487076

Abstract

Amaç: Diz
osteoartritli hastalarda merkezi maküla ve retina sinir lifi tabakası
kalınlıklarının değerlendirilmesi amaçlandı.

Gereç ve Yöntem: Bu
kesitsel ve karşılaştırmalı çalışmaya, 26 diz osteoartritli hastanın 26 gözü ve
yaş-cinsiyet olarak eşleştirilmiş 26 sağlıklı kontrolün 26 gözü alındı. Bütün
katılımcılara görme keskinliği ölçümü, biyomikroskopi değerlendirmesi, havalı
tonometre ile göz içi basınç ölçümü ve retina incelemesini içeren standart göz
muayenesi yapıldı. Merkezi maküla ve retina sinir lifi tabakası kalınlıklarını
ölçmek için optik koherens tomografi cihazı kullanıldı.

Bulgular: Diz
osteoartritli hastaların ve sağlıklı kontrollerin ortalama yaşları sırasıyla 60.8
± 8.2 ve 58.0 ± 9.8 yıldı (p=0.46). Her iki grupta da 8 erkek ve 18 kadın
katılımcı vardı (p=1.00). Ortalama merkezi maküla kalınlığı osteoartritli
hastalarda 264.2 ± 22.1 µm iken sağlıklı kontrollerde 262.9 ± 20.1 µm idi
(p=0.88). Ortalama retina sinir lifi tabakası kalınlığı osteoartritli
hastalarda 105.4 ± 9.9 µm iken sağlıklı kontrollerde 103.9 ± 10.1 µm idi
(p=0.81).

Sonuç:
Merkezi maküla ve retina sinir lifi tabakası kalınlıkları osteoartritli
hastalarda ve sağlıklı kontrollerde benzerdi.

Keywords

osteoartrit, merkezi maküla kalınlığı, retina sinir lifi tabakası

Evaluation of retinal thickness in patients with osteoarthritis

Abstract

Purpose: Our aim was to evaluate the thickness of central
macula and retinal nerve fiber layer in patients with knee osteoarthritis.

Methods: Twenty-six eyes of 26 patients with knee
osteoarthritis and 26 eyes of 26 age-gender matched healthy controls were
included in this cross-sectional and comparative study. All participants
underwent a standardized ophthalmological examination including visual acuity
assessment, biomicroscopy evaluation, air-puff tonometry measurement and
retinal examination. Optical coherence tomography was used to measure the
thickness of central macula and retinal nerve fiber layer.

Results:
The mean age of the
patients with knee osteoarthritis and healthy controls were 60.8 ± 8.2 and 58.0
± 9.8 years, respectively (p=0.46). In both groups, there were 8 male and 18
female participants (p=1.00). The mean central macular thickness was 264.2 ±
22.1 µm in the osteoarthritis group and 262.9 ± 20.1 µm in the healthy controls
(p=0.88). The mean retinal nerve fiber layer thickness was 105.4 ± 9.9 µm in
the osteoarthritis group and 103.9 ± 10.1 µm in the healthy controls (p=0.81).

Conclusions:
The thicknesses of
central macula and retinal nerve fiber layer were similar in patients with
osteoarthritis and healthy controls.

Keywords

osteoarthritis, central macular thickness, retinal nerve fiber layer

References

• Kaynaklar1. Mora JC, Przkora R, Cruz-Almeida Y. Knee osteoarthritis: pathophysiology and current treatment modalities. J Pain Res 2018;11:2189-2196.2. Nelson FRT. The Value of Phenotypes in Knee Osteoarthritis Research. Open Orthop J 2018;12:105-114.3. Gardiner BS, Woodhouse FG, Besier TF, Grodzinsky AJ, Lloyd DG, Zhang L, et al. Predicting Knee Osteoarthritis. Ann Biomed Eng 2016;44:222-233.4. Hoeven TA, Kavousi M, Clockaerts S, Kerkhof HJ, van Meurs JB, Franco O, et al. Association of atherosclerosis with presence and progression of osteoarthritis: the Rotterdam Study. Ann Rheum Dis 2013;72:646-651.5. Hussain SM, Wang Y, Shaw JE, Magliano DJ, Wong TY, Wluka AE, et al. Retinal arteriolar narrowing and incidence of knee replacement for osteoarthritis: a prospective cohort study. Osteoarthritis Cartilage 2015;23:589-593.6. Ruia S, Saxena S, Gemmy Cheung CM, Gilhotra JS, Lai TY. Spectral Domain Optical Coherence Tomography Features and Classification Systems for Diabetic Macular Edema: A Review. Asia Pac J Ophthalmol (Phila) 2016;5:360-367.7. Chhablani PP, Ambiya V, Nair AG, Bondalapati S, Chhablani J. Retinal Findings on OCT in Systemic Conditions. Semin Ophthalmol 2018;33:525-546.8. Patel PJ, Foster PJ, Grossi CM, Keane PA, Ko F, Lotery A, et al. Spectral-Domain Optical Coherence Tomography Imaging in 67321 Adults: Associations with Macular Thickness in the UK Biobank Study. Ophthalmology 2016;123:829-840. 9. Alkuraya H, Kangave D, Abu El-Asrar AM. The correlation between optical coherence tomographic features and severity of retinopathy, macular thickness and visual acuity in diabetic macular edema. Int Ophthalmol 2005;26:93-99. 10. Ingegnoli F, Gualtierotti R, Pierro L, Del Turco C, Miserocchi E, Schioppo T, et al. Choroidal impairment and macular thinning in patients with systemic sclerosis: the acute study. Microvasc Res 2015;97:31-36.11. Akay F, Gündoğan FC, Yolcu U, Toyran S, Tunç E, Uzun S. Retinal structural changes in systemic arterial hypertension: an OCT study. Eur J Ophthalmol. 2016;26:436-441.12. Townsend KA, Wollstein G, Schuman JS. Imaging of the retinal nerve fiber layer for glaucoma. Br J Ophthalmol 2009;93:139-143.13. Weinreb RN, Shakiba S, Sample PA, Shahrokni S, van Horn S, Garden VS, et al. Association between quantitative nerve fiber layer measurement and visual field loss in glaucoma. Am J Ophthalmol 1995;120:732-738.14. Zarei R, Anvari P, Eslami Y, Fakhraie G, Mohammadi M, Jamali A, et al. Retinal nerve fibre layer thickness is reduced in metabolic syndrome. Diabet Med 2017;34:1061-1066.15. Güneş A, Demirci S, Tök L, Tök Ö, Demirci S. Evaluation of retinal nerve fiber layer thickness in Alzheimer disease using spectral-domain optical coherence tomography. Turk J Med Sci 2015;45:1094-1097.