Research Article
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Nöroloji Kliniği'nde yatan hastalarda nutrisyonel durumun polifarmasi ve hastane yatış süresi ile ilişkisi

Year 2019, , 467 - 473, 30.09.2019
https://doi.org/10.31362/patd.535646

Abstract

Amaç : Malnutrisyon hastane
yatışı sırasında mevcut olabileceği gibi yatış sonrasında da ortaya
çıkabilmektedir. Hastanede yatan hastalarda malnutrisyon birçok klinik sonuç
ile ilişkilidir. Bu çalışmanın amacı nöroloji kliniğine yatan hastalarda nutrisyonel
durumun ve polifarmasi ve hastane yatış süresi ile ilişkisinin
değerlendirilmesidir.



Gereç ve Yöntem : Eylül 2017 - Eylül 2018 tarihleri arasında
Burdur Devlet Hastanesi nöroloji kliniğinde takip edilen 1422 hasta geriye
dönük dosya incelemesi şeklinde taranarak değerlendirdi. Hastaların nutrisyonel
durumları NRS-2002 skorları ile dosya üzerinden kayıt edildi. Toplam
skoru ≥3 olan hastalar malnutrisyon riski altında olarak kabul edildi.
Polifarmasi, altı ve daha fazla ilaç kullanımı olarak tanımlandı. Hastane yatış
süresi on günden uzun olan hastalar uzamış yatış süresi olarak değerlendirildi.
Normal nutrisyonel durum ve malnutrisyon riski altındaki hasta gruplarının
özellikleri t-testi ile karşılaştırıldı. Nutrisyonel risk, polifarmasi ve
hastane yatış süresi arasındaki ilişki korelasyon analizleri ile
değerlendirildi.



Bulgular : 760
kadın (%53,5), 662 erkek (%46,5) hasta çalışmaya alındı.
Hastane
başvurusu sırasında 656 hastada (%46,2) malnutrisyon riski saptanmaz iken 766
hasta (%53,8) malnutrisyon riski altında olarak değerlendirildi. Malnutrisyon
riski cinsiyetler arasında farklılık göstermemekle birlikte yaş artışı ile
ilişkili olarak saptandı. Malnutrisyon riski altındaki hastalarda malnutrisyon
riski olmayan hastalara göre anlamlı olarak daha uzun hastane yatış süreleri
saptandı (p<0.001). 328 hastada
(%23) polifarmasi olduğu görüldü. Malnutrisyon riskinin ilaç kullanım sayısı ve
hastane yatış süresi ile anlamlı olarak ilişkili olduğu görüldü (r:0.462, p<0.001 ; r:0.414, p<0.001).



Sonuç :
Özellikle ileri yaşta ve çoklu ilaç kullanımı olan hastalar malnutrisyon
açısından yakından takip edilmelidir. Hastanede yatan hastalarda malnutrisyonun
yaşlanma sürecinin veya altta yatan hastalıkların kaçınılmaz bir sonucu
olmadığı, ancak aktif yönetim gerektiren spesifik bir hastalık olduğu kabul
edilmelidir. 

References

  • 1. Barker LA, Gout BS, Crowe TC. Hospital malnutrition: prevalence, identification and impact on patients and the healthcare system. Int J Environ Res Public Health 2011;8(2):514-27.
  • 2. Allard JP, Keller H, Jeejeebhoy KN, Laporte M, Duerksen DR, Gramlich L, et al. Decline in nutritional status is associated with prolonged length of stay in hospitalized patients admitted for 7 days or more: a prospective cohort study. Clin Nutr 2016;35(1):144-52.
  • 3. Jebb SA. Incidence and recognition of malnutrition in hospital J. P. McWhirter and C. R. Pennington BMJ 1994; 308: 945-948. Clin Nutr. 1994;13(4):267-268.
  • 4. Kondrup J, Allison SP, Elia M, Vellas B, Plauth M. Educational and Clinical Practice Committee ErSoPaENE. ESPEN guidelines for nutrition screening 2002. Clin Nutr. 2003;22(4):415-421.
  • 5. Anthony PS. Nutrition screening tools for hospitalized patients. Nutr Clin Pract. 2008 2008;23(4):373-382.
  • 6. Fillit HM, Futterman R, Orland BI, Chim T, Susnow L, Picariello GP, et al. Polypharmacy management in Medicare managed care: changes in prescribing by primary care physicians resulting from a program promoting medication reviews. Am J Manag Care 1999;5:587–94.
  • 7. Jyrkka J, Enlund H, Lavikainen P, Sulkava R, Hartikainen S. Association of polypharmacy with nutritional status, functional ability and cognitive capacity over a three-year period in an elderly population. Pharmacoepidemiol Drug Saf 2011;20:514–522.
  • 8. Edington J, Boorman J, Durrant ER, Perkins A, Giffin CV, James R, et al. Prevalence of malnutrition on admission to four hospitals in England. The Malnutrition Prevalence Group. Clin Nutr 2000; 19: 191-5.
  • 9. Waitzberg DL, Caiaffa WT, Correia MI. Hospital malnutrition: the Brazilian national survey (IBRANUTRI): a study of 4000 patients. Nutrition 2001; 17: 573-80.
  • 10. Velasco C, Garcia E, Rodriguez V, Frias L, Garriga R, AlvarezJ, et al. Comparison of four nutritional screening tools to detect nutritional risk in hospitalized patients: a multicentre study. Eur J Clin Nutr 2011; 65: 269-74.
  • 11. Pirlich M, Schütz T, Norman K, Gastell S, Lübke HJ, Bischoff SC, et al. The German hospital malnutrition study. Clin Nutr 2006;25(4):563-72.
  • 12. Naber THJ, Schermer T, de Bree A, Nusteling K, Eggink L, Kruimel JW, et al. Prevalence of malnutrition in nonsurgical hospitalized patients and its association with disease complications. Am J Clin Nutr 1997;66:1232–9.
  • 13. Sacks GS, Dearman K, Replogle WH, Cora VL, Meeks M, Canada T. Use of subjective global assessment to identify nutritionassociated complications and death in geriatric long-term care facility residents. J Am Coll Nutr 2000;19:570–7.
  • 14. Lee H, Kang JH, Kim E, Kim WG. Prevalence of malnutrition in hospitalized elderly Korean patients based on mini nutritional assessment-short form. J Clin Nutr 2014;6(1):24-9.
  • 15. Kang MC, Kim JH, Ryu SW, Moon JY, Park JH, Park JK, et al. Prevelance of malnutrition in hospitalized patients: a multicenter cross-sectional study. J Korean Med Sci. 2018 Jan 8;33(2):e10.
  • 16. Vanderwee K, Clays E, Bocquaert I, Gobert M, Folens B, Defloor T. Malnutrition and associated factors in elderly hospital patients: a Belgian cross-sectional, multi-centre study. Clin Nutr 2010;29(4):469-76.
  • 17. Corsonello A, Pedone C, Corica F, Antonelli Incalzi R. Polypharmacy in the elderly patients at discharge from the acute care hospital. Therapeutics and Clinical Risk Management 2007:3:197–203.
  • 18. Wawruch M, Zikavska M, Wsolova L, Kuzelova M, Tisonova J, Gajdosik J et al. Polyphramacy in elderly hospitalised patients in Slovakia. Pharm World Sci 2008:30:235–242.
  • 19. Schuler J, Duckelmann C, Beindl W, Prinz E, Michalski T, Pichelr M. Polypharmacy and inappropriate prescribing in elderly internal medicine patients in Austria. Wien Klin Wochenschr 2008:120:733–741.
  • 20. Runciman WB, Roughead EE, Semple SJ, Adams RJ. Adverse drug events and medication errors in Australia. Int J Qual Health Care 2003; 15 (Suppl 1):i49–i59.
  • 21. Lisby M, Nielsen LP, Mainz J. Errors in the medication process: frequency, type, and potential. Int J Qual Health Care 2005; 17:15–22.
  • 22. Agostini JV, Han L, Tinetti ME. The relationship between number of medications and weight loss or impaired balance in older adults. J Am Geriatr Soc 2004; 52:1719–1723. DOI: 10.1111/j.1532-5415.2004.52467.x.
  • 23. Chen CCH, Tang ST, Wang C, Huang G-H. Trajectory and determinants of nutritional health in older patients during and six-month posthospitalisation. J Clin Nurs 2009; 18:3299–3307.
  • 24. Schilp J, Winjhoven HAH, Deeg DJH, Visser M. Early determinants for the development of undernutrition in an older general population: Longitudinal Aging Study Amsterdam. Br J Nutr 2011; 106:708–717.
  • 25. Norman K, Pichard C, Lochs H, Pirlich M. Prognostic impact of disease-related malnutrition. Clin Nutr 2008;27(1):5-15.
  • 26. Rasmussen HH, Kondrup J, Staun M, Ladefoged K, Kristensen H, Wengler A. Prevalence of patients at nutritional risk in Danish hospitals. Clin Nutr 2004;23:1009–15.
  • 27. Norman K, Lochs H, Pirlich M. Malnutrition as a prognostic factor. Chir Gastroenterol 2004;20:175–80.
  • 28. Sorensen J, Kondrup J, Prokopowicz J, Schiesser M, Krahenbuhl L, Meier R, et al. EuroOOPS: an international, multicentre study to implement nutritional risk screening and evaluate clinical outcome. Clin Nutr Edinb Scotl 2008;27:340e9.
  • 29. Khalatbari-Soltani S, Marques-Vidal P. The economic cost of hospital malnutrition in Europe; a narrative review. Clin Nutr ESPEN 2015;10:e89e94.
  • 30. Kondrup J, Johansen N, Plum LM, Bak L, Larsen IH, Martinsen A, et al. Incidence of nutritional risk and causes of inadequate nutritional care in hospitals. Clin Nutr Edinb Scotl 2002;21:461e8.
  • 31. O'Flynn J, Peake H, Hickson M, Foster D, Frost G. The prevalence of malnutrition in hospitals can be reduced: results from three consecutive cross-sectional studies. Clin Nutr 2005;24(6):1078-88.
  • 32. Johansen N, Kondrup J, Plum LM, Bak L, Nørregaard P, Bunch E, et al. Effect of nutritional support on clinical outcome in patients at nutritional risk. Clin Nutr 2004;23(4):539-50.
  • 33. Tappenden KA, Quatrara B, Parkhurst ML, Malone AM, Fanjiang G, Ziegler TR. Critical role of nutrition in improving quality of care: an interdisciplinary call to action to address adult hospital malnutrition. J Acad Nutr Diet 2013;113(9):1219-37.
  • 34. White H, Pieper C, Schmader K. The association of weight change in Alzheimer's Disease with severity of disease and mortality: a longitudinal analysis. J Am Geriatr Soc 1998;46:1223–7.
  • 35. Ongun Nedim. Does nutritional status affect Parkinson's Disease features and quality of life? PLoS One. 2018. Oct 2;13(10):e0205100. doi:10.1371/journal.pone.0205100. eCollection 2018.
  • 36. Dávalos A, Ricart W, Gonzalez-Huix F, Soler S, Marrugat J, Molins A, et al. Effect of malnutrition after acute stroke on clinical outcome. Stroke. 1996 Jun;27(6):1028-32.
  • 37. Hafsteinsdóttir TB, Mosselman M, Schoneveld C, Riedstra YD, Kruitwagen CL. Malnutrition in hospitalised neurological patients approximately doubles in 10 days of hospitalisation. J Clin Nurs. 2010 Mar; 19(5-6):639-48. doi: 10.1111/j.1365-2702.2009.03142.x.
  • 38. Clavé P, Terré R, de Kraa M, Serra M. Approaching oropharyngeal dysphagia. Rev Esp Enferm Dig. 2004 Feb;96(2):119-31.
  • 39. McWhirter JP, Pennington CR. Incidence and recognition of malnutrition in hospital. BMJ 1994;308:945–8.
  • 40. Khalatbari-Soltani S, Marques-Vidal P. Impact of nutritional risk screening in hospitalized patients on management, outcome and costs: a retrospective study. Clin Nutr 2016;35(6):1340-6.
  • 41. Omidvari AH, Vali Y, Murray SM, Wonderling D, Rashidian A. Nutritional screening for improving professional practice for patient outcomes in hospital and primary care settings. Cochrane Database Syst Rev 2013;(6):CD005539.
Year 2019, , 467 - 473, 30.09.2019
https://doi.org/10.31362/patd.535646

Abstract

References

  • 1. Barker LA, Gout BS, Crowe TC. Hospital malnutrition: prevalence, identification and impact on patients and the healthcare system. Int J Environ Res Public Health 2011;8(2):514-27.
  • 2. Allard JP, Keller H, Jeejeebhoy KN, Laporte M, Duerksen DR, Gramlich L, et al. Decline in nutritional status is associated with prolonged length of stay in hospitalized patients admitted for 7 days or more: a prospective cohort study. Clin Nutr 2016;35(1):144-52.
  • 3. Jebb SA. Incidence and recognition of malnutrition in hospital J. P. McWhirter and C. R. Pennington BMJ 1994; 308: 945-948. Clin Nutr. 1994;13(4):267-268.
  • 4. Kondrup J, Allison SP, Elia M, Vellas B, Plauth M. Educational and Clinical Practice Committee ErSoPaENE. ESPEN guidelines for nutrition screening 2002. Clin Nutr. 2003;22(4):415-421.
  • 5. Anthony PS. Nutrition screening tools for hospitalized patients. Nutr Clin Pract. 2008 2008;23(4):373-382.
  • 6. Fillit HM, Futterman R, Orland BI, Chim T, Susnow L, Picariello GP, et al. Polypharmacy management in Medicare managed care: changes in prescribing by primary care physicians resulting from a program promoting medication reviews. Am J Manag Care 1999;5:587–94.
  • 7. Jyrkka J, Enlund H, Lavikainen P, Sulkava R, Hartikainen S. Association of polypharmacy with nutritional status, functional ability and cognitive capacity over a three-year period in an elderly population. Pharmacoepidemiol Drug Saf 2011;20:514–522.
  • 8. Edington J, Boorman J, Durrant ER, Perkins A, Giffin CV, James R, et al. Prevalence of malnutrition on admission to four hospitals in England. The Malnutrition Prevalence Group. Clin Nutr 2000; 19: 191-5.
  • 9. Waitzberg DL, Caiaffa WT, Correia MI. Hospital malnutrition: the Brazilian national survey (IBRANUTRI): a study of 4000 patients. Nutrition 2001; 17: 573-80.
  • 10. Velasco C, Garcia E, Rodriguez V, Frias L, Garriga R, AlvarezJ, et al. Comparison of four nutritional screening tools to detect nutritional risk in hospitalized patients: a multicentre study. Eur J Clin Nutr 2011; 65: 269-74.
  • 11. Pirlich M, Schütz T, Norman K, Gastell S, Lübke HJ, Bischoff SC, et al. The German hospital malnutrition study. Clin Nutr 2006;25(4):563-72.
  • 12. Naber THJ, Schermer T, de Bree A, Nusteling K, Eggink L, Kruimel JW, et al. Prevalence of malnutrition in nonsurgical hospitalized patients and its association with disease complications. Am J Clin Nutr 1997;66:1232–9.
  • 13. Sacks GS, Dearman K, Replogle WH, Cora VL, Meeks M, Canada T. Use of subjective global assessment to identify nutritionassociated complications and death in geriatric long-term care facility residents. J Am Coll Nutr 2000;19:570–7.
  • 14. Lee H, Kang JH, Kim E, Kim WG. Prevalence of malnutrition in hospitalized elderly Korean patients based on mini nutritional assessment-short form. J Clin Nutr 2014;6(1):24-9.
  • 15. Kang MC, Kim JH, Ryu SW, Moon JY, Park JH, Park JK, et al. Prevelance of malnutrition in hospitalized patients: a multicenter cross-sectional study. J Korean Med Sci. 2018 Jan 8;33(2):e10.
  • 16. Vanderwee K, Clays E, Bocquaert I, Gobert M, Folens B, Defloor T. Malnutrition and associated factors in elderly hospital patients: a Belgian cross-sectional, multi-centre study. Clin Nutr 2010;29(4):469-76.
  • 17. Corsonello A, Pedone C, Corica F, Antonelli Incalzi R. Polypharmacy in the elderly patients at discharge from the acute care hospital. Therapeutics and Clinical Risk Management 2007:3:197–203.
  • 18. Wawruch M, Zikavska M, Wsolova L, Kuzelova M, Tisonova J, Gajdosik J et al. Polyphramacy in elderly hospitalised patients in Slovakia. Pharm World Sci 2008:30:235–242.
  • 19. Schuler J, Duckelmann C, Beindl W, Prinz E, Michalski T, Pichelr M. Polypharmacy and inappropriate prescribing in elderly internal medicine patients in Austria. Wien Klin Wochenschr 2008:120:733–741.
  • 20. Runciman WB, Roughead EE, Semple SJ, Adams RJ. Adverse drug events and medication errors in Australia. Int J Qual Health Care 2003; 15 (Suppl 1):i49–i59.
  • 21. Lisby M, Nielsen LP, Mainz J. Errors in the medication process: frequency, type, and potential. Int J Qual Health Care 2005; 17:15–22.
  • 22. Agostini JV, Han L, Tinetti ME. The relationship between number of medications and weight loss or impaired balance in older adults. J Am Geriatr Soc 2004; 52:1719–1723. DOI: 10.1111/j.1532-5415.2004.52467.x.
  • 23. Chen CCH, Tang ST, Wang C, Huang G-H. Trajectory and determinants of nutritional health in older patients during and six-month posthospitalisation. J Clin Nurs 2009; 18:3299–3307.
  • 24. Schilp J, Winjhoven HAH, Deeg DJH, Visser M. Early determinants for the development of undernutrition in an older general population: Longitudinal Aging Study Amsterdam. Br J Nutr 2011; 106:708–717.
  • 25. Norman K, Pichard C, Lochs H, Pirlich M. Prognostic impact of disease-related malnutrition. Clin Nutr 2008;27(1):5-15.
  • 26. Rasmussen HH, Kondrup J, Staun M, Ladefoged K, Kristensen H, Wengler A. Prevalence of patients at nutritional risk in Danish hospitals. Clin Nutr 2004;23:1009–15.
  • 27. Norman K, Lochs H, Pirlich M. Malnutrition as a prognostic factor. Chir Gastroenterol 2004;20:175–80.
  • 28. Sorensen J, Kondrup J, Prokopowicz J, Schiesser M, Krahenbuhl L, Meier R, et al. EuroOOPS: an international, multicentre study to implement nutritional risk screening and evaluate clinical outcome. Clin Nutr Edinb Scotl 2008;27:340e9.
  • 29. Khalatbari-Soltani S, Marques-Vidal P. The economic cost of hospital malnutrition in Europe; a narrative review. Clin Nutr ESPEN 2015;10:e89e94.
  • 30. Kondrup J, Johansen N, Plum LM, Bak L, Larsen IH, Martinsen A, et al. Incidence of nutritional risk and causes of inadequate nutritional care in hospitals. Clin Nutr Edinb Scotl 2002;21:461e8.
  • 31. O'Flynn J, Peake H, Hickson M, Foster D, Frost G. The prevalence of malnutrition in hospitals can be reduced: results from three consecutive cross-sectional studies. Clin Nutr 2005;24(6):1078-88.
  • 32. Johansen N, Kondrup J, Plum LM, Bak L, Nørregaard P, Bunch E, et al. Effect of nutritional support on clinical outcome in patients at nutritional risk. Clin Nutr 2004;23(4):539-50.
  • 33. Tappenden KA, Quatrara B, Parkhurst ML, Malone AM, Fanjiang G, Ziegler TR. Critical role of nutrition in improving quality of care: an interdisciplinary call to action to address adult hospital malnutrition. J Acad Nutr Diet 2013;113(9):1219-37.
  • 34. White H, Pieper C, Schmader K. The association of weight change in Alzheimer's Disease with severity of disease and mortality: a longitudinal analysis. J Am Geriatr Soc 1998;46:1223–7.
  • 35. Ongun Nedim. Does nutritional status affect Parkinson's Disease features and quality of life? PLoS One. 2018. Oct 2;13(10):e0205100. doi:10.1371/journal.pone.0205100. eCollection 2018.
  • 36. Dávalos A, Ricart W, Gonzalez-Huix F, Soler S, Marrugat J, Molins A, et al. Effect of malnutrition after acute stroke on clinical outcome. Stroke. 1996 Jun;27(6):1028-32.
  • 37. Hafsteinsdóttir TB, Mosselman M, Schoneveld C, Riedstra YD, Kruitwagen CL. Malnutrition in hospitalised neurological patients approximately doubles in 10 days of hospitalisation. J Clin Nurs. 2010 Mar; 19(5-6):639-48. doi: 10.1111/j.1365-2702.2009.03142.x.
  • 38. Clavé P, Terré R, de Kraa M, Serra M. Approaching oropharyngeal dysphagia. Rev Esp Enferm Dig. 2004 Feb;96(2):119-31.
  • 39. McWhirter JP, Pennington CR. Incidence and recognition of malnutrition in hospital. BMJ 1994;308:945–8.
  • 40. Khalatbari-Soltani S, Marques-Vidal P. Impact of nutritional risk screening in hospitalized patients on management, outcome and costs: a retrospective study. Clin Nutr 2016;35(6):1340-6.
  • 41. Omidvari AH, Vali Y, Murray SM, Wonderling D, Rashidian A. Nutritional screening for improving professional practice for patient outcomes in hospital and primary care settings. Cochrane Database Syst Rev 2013;(6):CD005539.
There are 41 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Research Article
Authors

Nedim Ongun 0000-0003-1694-5933

Publication Date September 30, 2019
Submission Date March 5, 2019
Acceptance Date June 21, 2019
Published in Issue Year 2019

Cite

AMA Ongun N. Nöroloji Kliniği’nde yatan hastalarda nutrisyonel durumun polifarmasi ve hastane yatış süresi ile ilişkisi. Pam Tıp Derg. September 2019;12(3):467-473. doi:10.31362/patd.535646
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