Abstract
Brenner
tumors are rare transitional cell tumors of the ovary. They are usually benign
tumors but rarely have borderline and malignant types. Most of the benign
Brenner tumors are small and are found incidentally. Our case was a 57 years
old woman who underwent laparotomy for ovarian cyst. On laparotomy a solid mass
was found on the left ovary. The left ovarian mass was excised and a
histopathological diagnosis of borderline (atypical proliferative) Brenner
tumor was made. In this paper, histopathological findings of this rare case are
presented and the literature is reviewed.
References
- 1-Aslan F, Paksoy S, Altun E. Overin bening brenner tümörü: Rastlantısal bir tanı. Balıkesir Medical Journal 2017;1:9-14.
- 2-Zheng R, Heller DS. Borderline Brenner tumor: A review of the literature. Arch Pathol Lab Med 2019;143:1278-1280. doi: 10.5858/arpa.2018-0285-RS
- 3- Vemavarapu L,Alatassi H,Moghadamfalahi M. Unusual presentation of benign cystic Brenner tumor with exuberant psammomatous calcifications. International Journal of Surgical Pathology 2011;19:120-122.
- 4-Ayık H, Bayramoğlu, Z, Aydin A, Pestereli H, Şimşek T. Borderline Brenner tumor with a concomitant mucinous tumor of the ovary: a case report. Eur Res J 2018;4:122-125. doi:10.18621/eurj.357653
- 5- Roth LM, Sternberg WH. Proliferating Brenner tumors. Cancer 1971;27:687-698.
- 6- Roma AA, Masand RP. Different staining patterns of ovarian Brenner tumor and the associated mucinous tumor. Ann Diagn Pathol. 2015;19:29-32. doi: 10.1016/j.anndiagpath.2014.12.002
- 7- Santini D, Gelli MC, Mazzoleni G, et al. Brenner tumor of the ovary: a correlative histologic, histochemical, immunohistochemical, and ultrastructural investigation. Hum Pathol 1989,20:787-795.
- 8- Ruggiero S, Ripetti V, Bianchi A, et al. A singular observation of a giant benign Brenner tumor of the ovary. Arch Gynecol Obstet 2011;284:513-516.doi: 10.1007/s00404-011-1930-x
- 9- Kuhn E, Ayhan A, Shihle M, Seidman JD, Kurman RJ. The pathogenesis of atypical proliferative Brenner tumor: an immunohistochemical and molecular genetic analysis. Mod Pathol 2014;27:231-237. doi: 10.1038/modpathol.2013.142
- 10- Ashok V, Chander B, Verma S , Soni A. Malignant Brenner tumor of ovary. J Obstet Gynaecol India 2014;64:148-149.doi: 10.1007/s13224-012-0235-8
Abstract
Brenner
tümörleri overin nadir görülen transizyonel hücreli tümörleridir. Genellikle
benign tümörlerdir ancak daha ender olarak borderline ve malign tipleri de
vardır. Benign Brenner tümörlerinin çoğu küçüktür ve rastlantısal olarak
bulunur. Olgumuz sol over kisti nedeni ile laparotomi yapılan 57 yaşında kadın
hastadır. Sol overdeki kitle eksize edildi ve histopatolojik incelemede
borderline (atipik proliferatif) Brenner tümörü tanısı konuldu. Yazımızda bu
nadir olgunun histopatolojik bulguları sunularak literatür gözden
geçirilmektedir.
Keywords
References
- 1-Aslan F, Paksoy S, Altun E. Overin bening brenner tümörü: Rastlantısal bir tanı. Balıkesir Medical Journal 2017;1:9-14.
- 2-Zheng R, Heller DS. Borderline Brenner tumor: A review of the literature. Arch Pathol Lab Med 2019;143:1278-1280. doi: 10.5858/arpa.2018-0285-RS
- 3- Vemavarapu L,Alatassi H,Moghadamfalahi M. Unusual presentation of benign cystic Brenner tumor with exuberant psammomatous calcifications. International Journal of Surgical Pathology 2011;19:120-122.
- 4-Ayık H, Bayramoğlu, Z, Aydin A, Pestereli H, Şimşek T. Borderline Brenner tumor with a concomitant mucinous tumor of the ovary: a case report. Eur Res J 2018;4:122-125. doi:10.18621/eurj.357653
- 5- Roth LM, Sternberg WH. Proliferating Brenner tumors. Cancer 1971;27:687-698.
- 6- Roma AA, Masand RP. Different staining patterns of ovarian Brenner tumor and the associated mucinous tumor. Ann Diagn Pathol. 2015;19:29-32. doi: 10.1016/j.anndiagpath.2014.12.002
- 7- Santini D, Gelli MC, Mazzoleni G, et al. Brenner tumor of the ovary: a correlative histologic, histochemical, immunohistochemical, and ultrastructural investigation. Hum Pathol 1989,20:787-795.
- 8- Ruggiero S, Ripetti V, Bianchi A, et al. A singular observation of a giant benign Brenner tumor of the ovary. Arch Gynecol Obstet 2011;284:513-516.doi: 10.1007/s00404-011-1930-x
- 9- Kuhn E, Ayhan A, Shihle M, Seidman JD, Kurman RJ. The pathogenesis of atypical proliferative Brenner tumor: an immunohistochemical and molecular genetic analysis. Mod Pathol 2014;27:231-237. doi: 10.1038/modpathol.2013.142
- 10- Ashok V, Chander B, Verma S , Soni A. Malignant Brenner tumor of ovary. J Obstet Gynaecol India 2014;64:148-149.doi: 10.1007/s13224-012-0235-8
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Obstetrics and Gynaecology |
| Journal Section | Case Report |
| Authors | |
| Publication Date | May 14, 2020 |
| Submission Date | November 23, 2019 |
| Acceptance Date | March 23, 2020 |
| Published in Issue | Year 2020 |
