The two cases presenting with skin rash: Could it be COVID-19?

Abstract

Abstract: Although the most common clinical findings of Coronavirus disease-19 (COVID-19) are fever, cough and difficulty in breathing, there are also findings related to other systems and organ involvement. There are increasing reports of dermatological symptoms. The timing of skin symptoms varies in COVİD-19 cases. Maculopapular rash, which is one of the common dermatological symptoms, may be associated with COVID-19 or may be seen in different clinical conditions such as drug reactions. This situation when evaluated together with the variations in the timing of findings, causes difficulties in differential diagnosis. In this report, two cases who were followed up with the diagnosis of COVID-19 and applied with symptoms of widespread maculopapular rash following the clinical recovery period are presented.

Keywords

• COVID-19
• cutaneous manifestations
• maculopapular rash

Deri döküntüsü ile başvuran iki olgu: COVİD-19 olabilir mi?

Abstract

Öz: Coronavirus hastalığı-19’un (COVİD-19) en yaygın klinik bulguları ateş, öksürük ve solunum güçlüğü olmakla birlikte diğer sistem ve organ tutulumlarına ait bulgular da mevcuttur. Dermatolojik bulgularla ilgili giderek artan bildirimler olmaktadır. COVİD-19 olgularında deri belirtilerinin zamanlaması değişkenlik göstermektedir. Sık görülen dermatolojik belirtilerden olan makülopapüler döküntüler COVİD-19 ile ilişkili olabileceği gibi, ilaç reaksiyonları gibi farklı klinik durumlarda da görülebilmektedir. Bu durum, bulguların zamanlamasındaki değişkenliklerle birlikte değerlendirildiğinde ayırıcı tanıda zorluklara neden olmaktadır. Bu yazıda COVİD-19 tanısıyla takip edilen ve klinik iyileşme dönemini takiben vücutta yaygın makulopapüler döküntü bulguları ile başvuran iki olgu sunulmuştur.

Keywords

• COVİD-19
• deri belirtileri
• makulopapüler döküntü

References

1. Referans1 Mackenzie JS, Smith DW. COVID-19: a novel zoonotic disease caused by a coronavirus from China: what we know and what we don’t Microbiology Australia, 2020,41(1),45-50 doi: 10.1071/MA20013
2. Referans2 Koska MC, Süslü H. Cutaneous Findings of COVID-19: A Review of the Literature. J Turk Acad Dermatol 2020;14(2):30-43
3. Referans3 Genovesea G, Moltrasio C, Berti E, Marzano, AV. Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives Dermatology 2021;237:1-12 doi: 10.1159/000512932
4. Referans4 Feldman SR, Freeman EE, Duffin KC, Corona R. Coronavirus disease 2019 (COVID-19): Cutaneous manifestations and issues related to dermatologic care. Available at: https://www.uptodate.com/contents/coronavirusdisease-2019-covid-19-cutaneousmanifestations-and-issues-related-todermatologic-care Last accessed:March 02, 2021
5. Referans5 Öner Ü, Akdeniz N. COVID-19 İle İlişkili Kutanöz Bulgular. Anadolu Kliniği Tıp Bilimleri Dergisi 25, Cilt 25, özel sayı 1: 294-299
6. Referans6 Freeman EE, McMahon D, Lipoff JB, Rosenbach M, Kovarik C, Desai SR, Fox LP. The spectrum of COVID-19–associated dermatologic manifestations: An international registry of 716 patients from 31 countries. Journal of the American Academy of Dermatology Oct;83(4), 1118-1129 doi: 10.1016/j.jaad.2020.06.1016
7. Referans7 Suchonwanit P, Leerunyakul K, Kositkuljorn C. Cutaneous manifestations in COVID-19: Lessons learned from current evidence. Journal of the American Academy of Dermatology 2020 Jul;83(1): e57-e60 doi: 10.1016/j.jaad.2020.04.094
8. Referans 8 McMahon DE, Gallman AE, Hruza GJ, Rosenbach M, Lipoff JB, Desai SR, at al. Long COVID in the skin: a registry analysis of COVID-19 dermatological duration. www.thelancet.com/infection Vol 21 March 2021

9. Referans9 Ng SM. Prolonged dermatological manifestation 4 weeks following recovery of COVID-19 in a child BMJ Case Reports 2020;13(8), e237056 doi: 10.1136/bcr-2020-237056