Retrospective comparison of the sociodemographic, clinical, radiological and laboratory findings of probable and definitive COVID-19 cases
Abstract
Purpose: We aimed to determine the number of possible and precise cases among the patients hospitalized in our clinic and to examine the differences between the sociodemographic, clinical, chest CT and laboratory findings of these two groups.
Materials and methods: The data of all patients hospitalized at the department of pulmonology service between March 13 as the date of the first case and May 5 with probable and definitive COVID-19 were evaluated retrospectively. Patient ward files and hospital data management system were examined. Chest CT findings of the patients were interpreted by two radiologists separately according to the CO-RADS classification blinded to clinical and PCR test results of the patients and then consensus was achieved with joint evaluation.
Results: A total of 99 patients, 38 RT-PCR positive, 61 RT-PCR negative, were included in the study. Neutrophil-to-lymphocyte ratio(NLR) values and lymphocyte count were lower at a statistically significant level in positive patients(respectively p=0.038, p=0.041). Similarly, CRP values were observed to be lower at a statistically significant level in positive patients(p=0.029). When the patients with RT-PCR(+) and RT-PCR(-) but with positive chest CT findings according to CO-RADS staging were compared, the values of WBC, LDH and CRP level was observed to be high were statistically significant in the group with RT-PCR(-) but positive chest CT findings.
Conclusion: In the presence of clinical findings, without waiting for RT-PCR positivity, the probability of COVID-19 disease will increase if there are elevated WBC, CRP and LDH findings with CT findings(stage 4-5 according to CO-RADS).
Keywords
CO-RADS, Probable COVID-19, RT-PCR, SARS-CoV-2
Supporting Institution
None
References
- Yan Y, Shin WI, Pang YX, et al. The First 75 Days of Novel Coronavirus (SARS-CoV-2) Outbreak: Recent Advances, Prevention, and Treatment. Int J Environ Res Public Health 2020;17(7):2323.
- Yan Y, Shin WI, Pang YX, et al. The First 75 Days of Novel Coronavirus (SARS-CoV-2) Outbreak: Recent Advances, Prevention, and Treatment. Int J Environ Res Public Health 2020;17(7):2323.
- Sarzi-Puttini P, Giorgi V, Sirotti S, et al. COVID-19, cytokines and immunosuppression: what can we learn from severe acute respiratory syndrome? Clin Exp Rheumatol 2020;38(2):337-342.
- Sarzi-Puttini P, Giorgi V, Sirotti S, et al. COVID-19, cytokines and immunosuppression: what can we learn from severe acute respiratory syndrome? Clin Exp Rheumatol 2020;38(2):337-342.
- Wujtewicz M, Dylczyk-Sommer A, Aszkiełowicz A, Zdanowski S, Piwowarczyk S, Owczuk R. COVID-19 - what should anaethesiologists and intensivists know about it? Anaesthesiol Intensive Ther 2020;52(1):34-41.
- Wujtewicz M, Dylczyk-Sommer A, Aszkiełowicz A, Zdanowski S, Piwowarczyk S, Owczuk R. COVID-19 - what should anaethesiologists and intensivists know about it? Anaesthesiol Intensive Ther 2020;52(1):34-41.
- TC. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü COVID-19 (Sars-CoV-2) enfeksiyonu rehberi. Avaliable at: https://covid19bilgi.saglik.gov.tr/depo/rehberler/COVID-19_Rehberi.pdf. Accessed March 20, 2021.
- TC. Sağlık Bakanlığı Halk Sağlığı Genel Müdürlüğü COVID-19 (Sars-CoV-2) enfeksiyonu rehberi. Avaliable at: https://covid19bilgi.saglik.gov.tr/depo/rehberler/COVID-19_Rehberi.pdf. Accessed March 20, 2021.
- Ai T, Yang Z, Hou H, et al. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology 2020;296(2):E32-E40.
- Ai T, Yang Z, Hou H, et al. Correlation of Chest CT and RT-PCR Testing for Coronavirus Disease 2019 (COVID-19) in China: A Report of 1014 Cases. Radiology 2020;296(2):E32-E40.
