Schizencephaly

Year 2022, , 201 - 204, 01.01.2022

Büşra Şirin , Nur Kesiktaş , Sedef Ersoy

https://doi.org/10.31362/patd.904424

Abstract

Abstract: Schizencephaly, a neuronal migration abnormality, is characterized with clefts that extend from the pial membrane to the ependymal surface of the lateral ventricle. Patients usually present with mental retardation, hemiparesis, developmental deficits and epileptic seizures. The most common causes of schizencephaly are prenatal infections, maternal trauma, hypoxemia and EMX2 mutations. The method of choice in diagnosis of schizencephaly is magnetic resonance imaging. In this case report, an 11-month-old male infant with schizencephaly will be presented.

Keywords

Schizencephaly, rehabilitation, cortical dysplasia

Şizensefali

Abstract

Öz: Şizensefali, pial membrandan lateral ventrikül ependimal yüzeyine uzanan yarıklarla karakterize bir nöronal migrasyon anomalisidir. Hastalar genellikle mental retardasyon, hemiparezi, gelişimsel defisitler ve epileptik nöbetlerle prezente olmaktadır. Şizensefalinin en yaygın sebepleri prenatal infeksiyonlar, maternal travma, hipoksemi ve EMX2 mutasyonlarıdır. Şizensefali tanısında tercih edilen yöntem manyetik rezonans görüntülemedir. Bu olgu sunumunda şizensefali saptanan 11 aylık erkek bebek sunulacaktır.

Keywords

Şizensefali, rehabilitasyon, kortikal displazi

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