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Ryanodin reseptörlerinin santral sinir sistemi üzerindeki rolleri

Year 2017, Volume: 10 Issue: 1, 115 - 119, 01.04.2017

Elif Karabacak-taşdemir Salim Yalçın İnan Ayşe Saide Şahin

Abstract

Ryanodin reseptörleri (RyR) endoplazmik retikulumdan kalsiyum iyonu salıverilmesine neden olan iyon kanallarıdır. Kasların uyarılmasından ve kasılmasından sorumludurlar. Bununla beraber, son yıllarda RyR’nin kas-iskelet hastalıklarından, kardiyak aritmilerden, çeşitli kalıtsal hastalıklardan ve santral sinir sistemi ile ilgili nörodejeneratif bozukluklardan sorumlu olduğu gösterilmiştir. Bu derlemede RyR’nin santral sinir sistemi üzerindeki etkilerini inceledik.

Keywords

Ryanodin reseptörleri santral sinir sistemi kalsiyum nörodejenerasyon

Roles of ryanodine receptors in the central nervous system

Year 2017, Volume: 10 Issue: 1, 115 - 119, 01.04.2017

Elif Karabacak-taşdemir Salim Yalçın İnan Ayşe Saide Şahin

Abstract

Ryanodine receptors (RyR) are important for calcium release from endoplasmic reticulum and they are also responsible for muscle excitability and contraction. Besides, it has recently been shown that, alteration in RyR can cause musculoskeletal diseases, cardiac arrhythmias, various hereditary diseases and neurodegenerative disorders in the central nervous system. In the present review, we aimed to investigate the effects of RyR in the central nervous system.

Keywords

Ryanodine receptors and central nervous system

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Details

Other ID JA45KB55KP
Journal Section Collection
Authors

Elif Karabacak-taşdemir This is me

Salim Yalçın İnan This is me

Ayşe Saide Şahin This is me

Publication Date April 1, 2017
Submission Date April 1, 2017
Published in Issue Year 2017 Volume: 10 Issue: 1

Cite

APA Karabacak-taşdemir, E., İnan, S. Y., & Şahin, A. S. (2017). Roles of ryanodine receptors in the central nervous system. Pamukkale Medical Journal, 10(1), 115-119.
AMA Karabacak-taşdemir E, İnan SY, Şahin AS. Roles of ryanodine receptors in the central nervous system. Pam Med J. April 2017;10(1):115-119.
Chicago Karabacak-taşdemir, Elif, Salim Yalçın İnan, and Ayşe Saide Şahin. “Roles of Ryanodine Receptors in the Central Nervous System”. Pamukkale Medical Journal 10, no. 1 (April 2017): 115-19.
EndNote Karabacak-taşdemir E, İnan SY, Şahin AS (April 1, 2017) Roles of ryanodine receptors in the central nervous system. Pamukkale Medical Journal 10 1 115–119.
IEEE E. Karabacak-taşdemir, S. Y. İnan, and A. S. Şahin, “Roles of ryanodine receptors in the central nervous system”, Pam Med J, vol. 10, no. 1, pp. 115–119, 2017.
ISNAD Karabacak-taşdemir, Elif et al. “Roles of Ryanodine Receptors in the Central Nervous System”. Pamukkale Medical Journal 10/1 (April 2017), 115-119.
JAMA Karabacak-taşdemir E, İnan SY, Şahin AS. Roles of ryanodine receptors in the central nervous system. Pam Med J. 2017;10:115–119.
MLA Karabacak-taşdemir, Elif et al. “Roles of Ryanodine Receptors in the Central Nervous System”. Pamukkale Medical Journal, vol. 10, no. 1, 2017, pp. 115-9.
Vancouver Karabacak-taşdemir E, İnan SY, Şahin AS. Roles of ryanodine receptors in the central nervous system. Pam Med J. 2017;10(1):115-9.

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