Differentiation of benign thyroid nodules from malignant ones using European thyroid imaging reporting and data system (EU-TIRADS)

Year 2019, Volume: 12 Issue: 3, 445 - 455, 30.09.2019

Ergin Sağtaş , Erkan Demirci

https://doi.org/10.31362/patd.571516

Abstract

Conclusion: EU-TIRADS is an easy tool to apply and it is reliable in prediction of malignancy risk of thyroid nodules.

Results: FNAB was performed in 196 nodules. Twenty-seven (14%)  nodules were histopathologically diagnosed as malignant. The risk of malignancy of TIRADS 2, 3, 4, and 5 was 0%, 2.2%, 5.1%, 59,5%, respectively. Considering TIRADS 2, 3, and 4 as probable benign and TIRADS 5 as probable malignant, the sensitivity, specificity, positive predictive value, and negative predictive value were found to be as 0.82, 0.91, 0.60, and 0.97, respectively. The overall accuracy of ultrasound was determined as 0.90.

Materials and methods: In all, 156 patients who underwent ultrasound-guided FNAB of thyroid between May 2013 and May 2016 were included in this retrospective study. Ultrasound images were reviewed, and ultrasound-guided FNAB results were obtained. With the use of EU-TIRADS classification, each nodule was categorized as TIRADS from 1 to 5 according to its ultrasound features.

Purpose: It is essential to predict the malignancy risk in thyroid nodules. For this purpose, thyroid imaging reporting and data system (TIRADS) classification system can be used to evaluate malignancy risk and plan the treatment strategy. The aim of this study is to evaluate the clinical feasibility and reliability of European-TIRADS (EU-TIRADS) classification.

Keywords

TIRADS, fine needle aspiration biopsy, thyroid nodule, ultrasound

Avrupa tiroid görüntüleme raporlama ve veri sistemi (EU-TIRADS) kullanılarak benign ve malign tiroid nodüllerinin ayırımı.

Abstract

Amaç: Tiroid nodüllerinde
malignite riskini tahmin etmek esastır. Bu amaçla, TIRADS sınıflandırma sistemi
malignite riskini değerlendirmek ve tedavi stratejisini planlamak için
kullanılabilir. Bu çalışmanın amacı, EU-TIRADS sınıflamasının klinik
uygulanabilirliğini ve güvenilirliğini değerlendirmektir.

Gereç
ve Yöntem: Bu retrospektif çalışmaya Mayıs 2013 ile Mayıs 2016 tarihleri arasında
ultrason eşliğinde tiroid İİAB yapılan 156 hasta dahil edildi. Ultrason
görüntüleri incelendi ve ultrason rehberliğinde İİAB sonuçları elde olundu.
EU-TIRADS sistemi kullanılarak her bir nodül, ultrason özelliklerine göre TIRADS
1 ile 5 arasında sınıflandırılmıştır.

Bulgular: Yüz doksan altı nodüle İİAB yapıldı. Yirmi yedi (%14) nodül
histopatolojik olarak malign teşhis edildi. TIRADS 2, 3, 4 ve 5 malignite riski
sırasıyla %0 ,%2,2, %5,1, %59,5 idi. TIRADS 2, 3 ve 4'ün muhtemel benign ve
TIRADS 5'in muhtemel malign olduğu düşünüldüğünde; duyarlılık, özgüllük,
pozitif prediktif değer ve negatif prediktif değer, sırasıyla 0,82, 0,91, 0,60 ve
0,97 bulundu. Ultrasonun genel tanısal doğruluğu 0,90 olarak belirlenmiştir.

Sonuç:
EU-TIRADS uygulaması
kolay bir yöntemdir ve tiroid nodüllerinin malignite riskini tahmin etmede
güvenilirdir.

Keywords

TIRADS, ince iğne aspirasyon biyopsisi, tiroid nodülü, ultrasonografi

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