Evaluation of clinical and demographic data of children with chronic spontaneous urticaria in Antalya province.

Year 2020, Volume: 13 Issue: 1, 129 - 135, 21.01.2020

Serkan Filiz

https://doi.org/10.31362/patd.581096

Abstract

Purpose: The aim of the study was to
investigate the etiology of chronic urticaria in children and the related
clinical and laboratory findings in our city.

Materials
and methods: 107 patients aged between 7-17 years who were diagnosed with CSU in our clinic
were retrospectively reviewed. Demographic and clinical characteristics were
evaluated. In addition, Urticaria Activity Score (UAS) and Urticaria Control
Test (UCT) were applied to evaluate disease severity.

Results:
A total
of 107 patients with a mean age of 11.99±3.34
were evaluated. Angioedema was associated with 66%
of the patients. The mean duration of urticaria was 13.5±15.10 months. Allergic diseases were associated with 36% of the
patients. 12% of patients had asthma and 21% had allergic rhinitis. In 33% of
cases, inhalant sensitivity and 6.5% of food sensitivity were determined.
Antinuclear antibody (ANA) positivity was found in 16.8%, thyroid autoantibody
was present in 6.5%, urinary tract infection
was found in 3%, helicobacter pylori positivity was found in 1.9% and had
positive stool examination for parasites. The mean UAS7 was 12.96±9.8 and the mean
UCT was 8.43±2.8. No significant difference
was found between the groups in terms of age, gender, presence of angioedema,
duration of disease and ANA positivity when compared with control (n=24) and uncontrolled (n=83) patients (respectively, p=0.842,
p=0.646, p=0.347, p=0.590, p=0.316).

Conclusion:
In
children, atopic diseases, infections, parasitic infestations are present in
the etiology of CSF, where as in most cases the diagnosis remains idiopathic.

Keywords

Chronic urticaria, childhood, autoimmune thyroiditis, urticaria control test, urticaria activity scoring

Antalya il merkezinde kronik spontan ürtikeri olan çocukların klinik ve demografik verilerinin değerlendirilmesi.

Abstract

Amaç: Çalışmada, ilimizdeki çocuklarda KSÜ etiyolojisinde
rol oynayabilecek faktörler ve ilişkili klinik ve laboratuvar bulguların
araştırılması amaçlandı.

Yöntemler: Kliniğimizde KSÜ tanısı alan 7-17
yaş arası 107 hastanın kayıtları retrospektif olarak incelendi.  KSÜ’lü hastaların demografik ve klinik
özellikleri, laboratuvar bulguları, atopi, enfeksiyon, otoimmüniteye yönelik
tetkikleri değerlendirildi. Ek olarak hastalık şiddetinin
değerlendirilmesi için Ürtiker Aktivite Skoru (ÜAS7)  ve hastalık kontrolünün değerlendirilmesi
için Ürtiker Kontrol Testi (ÜKT) uygulandı.

Bulgular:
Ortalama yaşı 11,99.2±3,34 olan 107 hasta çalışmaya dahil edildi. Hastaların
%66’sına anjioödem eşlik etmekteydi. 
Ürtiker ortalama süresi 13,5±15,10 ay idi.  Hastaların %36’sına alerjik hastalıklar eşlik
etmekte idi. Hastaların %12’sinde astım ve %21’inde alerjik rinit öyküsü vardı.
Olguların %33’ünde inhalen duyarlılığı ve 
% 6,5’inde besin alerjen duyarlılığı saptandı. %16,8’inde antinükleer antikor
(ANA) pozitifliği, %6,5’inde tiroid otoantikor varlığı, %3’ünde idrar yolu
enfeksiyonu, %1,9’ unda helikobakter pylori pozitifliği ve gaitada parazit
tespit edildi.ÜAS7 ortalaması 12,96±9,8 ve ÜKT ortalaması 8,43±2,8 idi. ÜKT kontrollü (n=24) ve kontrolsüz
(n=83) olan hastalar karşılaştırıldığında, yaş cinsiyet, anjioödem varlığı,
hastalık süresi ve ANA pozitifliği açısından gruplar arasında anlamlı bir fark
saptanmadı (sırasıyla, p=0,842, p=0,646, p=0,34, p=0,590, p=0,316).

Sonuç: Çocuklarda KSÜ etiyolojisinde
atopik hastalıklar, enfeksiyonlar, paraziter enfestasyonlar yer tutarken çoğu
vakada tanı idiyopatik olarak kalmaktadır.

Keywords

Kronik ürtiker, çocuklar, otoimmün tiroidit, otoimmün tiroidit, ürtiker kontrol test, ürtiker aktivite skorlaması

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