Yumurta allerjisi olan çocuklarda kızamık-kızamıkçık-kabakulak aşılaması sonrası reaksiyon durumunun değerlendirilmesi

Year 2020, Volume: 13 Issue: 3, 687 - 693, 18.09.2020

Şennur Keleş , Serkan Filiz

https://doi.org/10.31362/patd.707081

Abstract

Amaç: Yumurta alerjisi olan çocuklara içerisinde yumurta proteini bulunan
kızamık-kızamıkçık-kabakulak (KKK) aşısının doğrudan uygulanması önerilmesine
rağmen hekimler genellikle çekince yaşamakta, bu durum hekim ve ailelerde
sıkıntılara yol açmaktadır. Bu çalışmamızda, kliniğimizde yumurta alerjisi
nedeniyle izlenen hastalarda, KKK aşısı sonrası aşı reaksiyon sıklığının
değerlendirilmesi amaçlanmıştır.

Yöntem: Kliniğimizde yumurta alerjisi tanısı ile izlenen hastaların Ocak 2019-Ocak
2020 tarihleri arasında KKK aşı kayıtları incelendi. KKK aşısı yapılan
hastaların demografik ve klinik özellikleri, laboratuvar bulguları
değerlendirildi.

Bulgular: Tanı anında yaş ortalaması 6,1±2,7 ay olan 80 hastanın %62,5’i (n=50)
erkek idi. Hastaların %68,8’inde (n=55) atopik dermatit, %18,8’inde (n=15)
ürtiker- anjioödem, %25’inde (n=20) reaktif hava yolu hastalığı, %15’inde
(n=12) anafilaksi, %16,3’ünde (n=13) proktokolit mevcuttu. Tüm hastalara KKK
aşısı aşı ile test yapılmadan, tek dozda uygulandı. Bir hastada aşıdan 30
dakika sonra aşırı ağlama, huzursuzluk ve yüzde kızarıklık şeklinde reaksiyon
gözlenirken antihistaminik sonrası 1 saat içinde şikayetleri geriledi. Diğer
hastalarda izlemlerinde sorun yaşanmadı.

Sonuç: Yumurta alerjili hastalarda KKK aşısı sonrası herhangi bir ciddi
reaksiyon gözlenmemiştir. Bağışıklama ve yapılma zamanı önemli olması nedeniyle
yumurta alerjisi olan hastalarda KKK aşısının güvenle yapılabileceğini düşünüyoruz.
Ancak aşı yapılan merkezlerde olası reaksiyonlara müdahale edilebilir uygun
koşullar sağlanmalı ve aşı sonrası hastalar uygun süre gözlem altında
bulundurulmalıdır.

Keywords

çocuk, yumurta alllerjisi, kızamık-kızamıkçık-kabakulak aşılama

The evaluation of allergic reaction in children with egg allergy after measles-mumps-rubella vaccination

Abstract

Objective: Although direct administration of the measles -mumps -rubella (MMR)
vaccine which contains egg protein is recommended to children with egg allergy,
physicians often have reservations, this situation leads to problems in
physicians and families. In this study, we aimed to evaluate the frequency of
reaction after the MMR vaccine in patients who were monitored for egg allergy
in our clinic.

Methods: MMR vaccination records were examined between January 2019 and January
2020 of patients diagnosed with egg allergy in our clinic. Demographic and
clinical characteristics, laboratory findings were evaluated in patients
vaccinated with MMR

Results: The average age was 6.1±2.7 months, and 62.5% (n=50) of the cases were
male. According to their diagnostic distribution, the patients had atopic
dermatitis (n=55; 68.8%), urticaria (n=15; 18.8%), reactive airway disease
(n=20; 25%), proctocolitis (n=13; 16.3%) and anaphylaxis (n=12; 15%). A whole
dose of vaccine was administered to all cases. Flushing and crying was observed
in one patient 30 minutes after vaccination, while her complaints resolved
1hour after antihistamine. No problems were observed in the follow-up of other
patients. There was no severe side effect in any of the cases.

Conclusion: No serious reactions have been observed in patients with egg allergy
after the MMR vaccine. We believe that the MMR vaccine can be safely
administered in patients with egg allergy in vaccinated centers, as
immunization and delivery time are important. However, appropriate conditions
can be intervened in possible reactions and patients should be kept under
observation for the appropriate period after vaccination.

Keywords

children, egg allergy, measles-mumps-rubella vaccination

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