Research Article
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Disfajisi olan çocukların değerlendirilmesi

Year 2024, Volume: 17 Issue: 2, 215 - 224, 01.04.2024
https://doi.org/10.31362/patd.1343219

Abstract

Amaç: Yutma güçlüğü; alınan gıdanın ağızdan mideye transferinin mekanik olarak engellenmesi sonucu oluşan semptomdur. Akut ve kronik hastalıklara bağlı olabilir. Pediatrik popülasyonda sağlıklı ve kronik hastalığı olan çocuklarda, orofarengeal ve özofageal her iki tip disfajiyi kapsayan, özelliklerini karşılaştıran çalışma sayısı az olması nedeniyle sunulmuştur.
Gereç ve yöntem: Mayıs 2019 ve Kasım 2020 arasında disfaji şikayeti ile başvuran 201 çocuk hasta dahil edildi. Disfaji tiplerine göre gruplandırıldı.
Bulgular: Grup-1 orofarengeal disfaji olan 80 çocuk hastadan oluşurken grup-2 özofageal disfaji olan 121 çocuk hastadan oluşmaktaydı. Hastaların %51,7 kız, ortalama yaş 9,4 yıldı. Grup-2 de tüm hastalarda katı gıda disfajisi varken, Grup-1’de %27 sıvı %53 katı-sıvı disfaji vardı. Güvenli oral beslenemeyen 50 çocuk hastaya perkütan endoskopik gastrostomi tüpü; 4 çocuk hastaya nazogastrik beslenme tüpü yerleştirildi. Hastaların %72,6 özofagogastroduodenoskopi yapıldı, %55,4’ünde özefagus patolojisi saptandı.
Sonuç: Disfajinin kronik hastalığı olan çocuklarda görülme sıklığı yüksek olsa da sağlıklı çocuklarda da görülebileceği ve tedavi edilebilir hastalıklarla ilişkili olabileceği unutulmamalıdır.

References

  • 1. Cho SY, Choung RS, Saito YA, et al. Prevalence and risk factors for dysphagia: a USA community study. Neurogastroenterol Motil 2015;27:212-219. https://doi.org/10.1111/nmo.12467
  • 2. Dodrill P, Gosa MM. Pediatric dysphagia: physiology, assessment, and management. Ann Nutr Metab 2015;66:24-31. https://doi.org/10.1159/000381372
  • 3. Kuo P, Holloway RH, Nguyen NQ. Current and future techniques in the evaluation of dysphagia. J Gastroenterol Hepatol 2012;27:873-881. https://doi.org/10.1111/j.1440-1746.2012.07097.x
  • 4. Bhattacharyya N. The prevalence of pediatric voice and swallowing problems in the United States. Laryngoscope 2015;125:746-750. https://doi.org/10.1002/lary.24931
  • 5. Manikam R, Perman JA. Pediatric feeding disorders. J Clin Gastroenterol 2000;30:34-46. https://doi.org/10.1097/00004836-200001000-00007
  • 6. Kakodkar K, James W. Schroeder Jr. Pediatric dysphagia. Pediatr Clin N Am 2013:60:969-977. http://dx.doi.org/10.1016/j.pcl.2013.04.010
  • 7. Arvedson JC. Assessment of pediatric dysphagia and feeding disorders: clinical and instrumental approaches. Dev Disabil Res Rev 2008;14:118-127. https://doi.org/10.1002/ddrr.17
  • 8. Svystun O, Johannsen W, Persad R, Turner JM, Majaesic C, El Hakim H. Dysphagia in healthy children characteristics and management of a consecutive cohort at a tertiary centre. Int J Pediatr Otorhinolaryngol 2017;99:54-59. https://doi.org/10.1016/j.ijporl.2017.05.024
  • 9. Lefton Greif MA, Okelo SO, Wright JM, Collaco JM, McGrath Morrow SA, Eakin MN. Impact of children's feeding/swallowing problems validation of a new caregiver instrument. Dysphagia 2014;29:671-677. https://doi.org/10.1007/s00455-014-9560-7
  • 10. Sheikh S, Allen E, Shell R, et al. Chronic aspiration without gastroesophageal reflux as a cause of chronic respiratory symptoms in neurologically normal infants. Chest 2001;120:1190-1195. https://doi.org/10.1378/chest.120.4.1190
  • 11. Duffy Kimberly LMA. Dysphagia in children. Curr Probl Pediatr Adolesc Health Care 2018;48:71-73. https://doi.org/10.1016/j.cppeds.2018.01.003
  • 12. Steele CM, Cichero JA. Physiological factors related to aspiration risk: a systematic review. Dysphagia 2014;29:295-304. https://doi.org/10.1007/s00455-014-9516-y
  • 13. Lefton Greif MA. Pediatric dysphagia. Phys Med Rehabil Clin N Am 2008;19:837-851. https://doi.org/10.1016/j.pmr.2008.05.007
  • 14. Lefton Greif MA, Carroll JL, Loughlin GM. Long-term follow-up of oropharyngeal dysphagia in children without apparent risk factors. Pediatr Pulmonol 2006;41:1040-1048. https://doi.org/10.1002/ppul.20488
  • 15. Hiorns MP, Ryan MM. Current practice in paediatric videofluoroscopy. Pediatric Radiology 2006;36:911-919. https://doi.org/10.1007/s00247-006-0124-3
  • 16. Benfer KA, Weir KA, Boyd RN. Clinimetrics of measures of oropharyngeal dysphagia for preschool children with cerebral palsy and neurodevelopmental disabilities a systematic review. Dev Med Child Neurol 2012;54:784-795. https://doi.org/10.1111/j.1469-8749.2012.04302.x
  • 17. Stabler SP, Allen RH, Savage DG. Lindenbaum J. Clinical spectrum and diagnosis of cobalamin deficiency. Blood 1990;76:871-881.
  • 18. Rasmussen SA, Fernhoff PM, Scanlon KS. Vitamin B12 deficiency in children and adolescents. J Pediatr 2001;138:10-17. https://doi.org/10.1067/mpd.2001.112160
  • 19. Lawlor CM, Choi S. Diagnosis and management of pediatric dysphagia a review. JAMA Otolaryngol Head Neck Surg 2020;146:183-191. https://doi.org/10.1001/jamaoto.2019.3622
  • 20. Godino J, Wong PW. A triad of troubling findings. Postgrad Med 2000;108:109-110. https://doi.org/10.3810/pgm.2000.08.1198
  • 21. Dantas RO, Villanova MG. Esophageal motility impairment Plummer-Vinson syndrome. Correction by iron treatment. Dig Dis Sci 1993;38:968-971. https://doi.org/10.1007/BF01295930
  • 22. Novacek G. Plummer-Vinson syndrome. Orphanet J Rare Dis 2006;1:36. https://doi.org/10.1186/1750-1172-1-36 23. Schatzki R. The lower esophageal ring. Long term follow-up of symptomatic and asymptomatic rings. Am J Roentgenol Radium Ther Nucl Med 1963;90:805-810.
  • 24. Müller M, Gockel I, Hedwig P, et al. Is the Schatzki ring a unique esophageal entity? World J Gastroenterol 2011;17:2838-2843. https://doi.org/10.3748/wjg.v17.i23.2838
  • 25. Akın M. Schatzki’s ring (Lower esophageal mucosal ring). Turkiye Klinikleri J Gen Surg Special Topics 2012;5:116-120.
  • 26. Mutaf O. Caustic esophageal burns in children. Journal of Pediatric Surgery 1988;2:69-85.
  • 27. Moulin D, Bertrand JM, Buts JP, Nyakabasa M, Otte JB. Upper airvay lesions in children after accidental ingestion of caustic substances. J Pediatr 1985;106:408-410. https://doi.org/10.1016/s0022-3476(85)80665-x
  • 28. Kutlu T, Çullu F, Erkan T, Aji D, Tümay G.T. Korozif madde içen çocukların değerlendirilmesi. Türk Pediatri Arşivi 1998;33:92-98.
  • 29. Previtera C, Giusti F, Guglielmi M. Predictive value of visible lesions (cheeks, lips, oropharynx)in suspected caustic ingestion may endoscopy reasonably be omitted in completely negative pediatric patients? Pediatr Emerg Care 1990;6:176-178. https://doi.org/10.1097/00006565-199009000-00002
  • 30. Zaninotto G, Bennett C, Boeckxstaens G, et al. The 2018 ISDE achalasia guidelines. Diseases of the Esophagus 2018;31:1-29. https://doi.org/10.1093/dote/doy071
  • 31. Huoha KC, Messner AH. Cricopharyngeal achalasia in children indications for treatment and management options. Curr Opin Otolaryngol Head Neck Surg 2013;21:576-580. https://doi.org/10.1097/01.moo.0000436789.29814.62
  • 32. Franklin AL, Petrosyan M, Kane TD. Childhood achalasia acomprehensive review of disease, diagnosis and therapeutic management. World J Gastrointest Endosc 2014;6:105-111. https://doi.org/10.4253/wjge.v6.i4.105
  • 33. Domingues GR, Lemme EM. Differential diagnosis of esophageal motor disorders based in characteristics of dysphagia. Arq Gastroenterol 2001;38:14-18. https://doi.org/10.1590/s0004-28032001000100004
  • 34. Zhang Y, Xu CD, Zaouche A, Cai W. Diagnosis and management of esophageal achalasia in children: analysis of 13 cases. World J Pediatr 2009;5:56-59. https://doi.org/10.1007/s12519-009-0010-9
  • 35. Hussain SZ, Thomas R, Tolia V. A review of achalasia in 33 children. Dig Dis Sci 2002;47:2538-2543. https://doi.org/10.1023/a:1020572328777
  • 36. Kahrilas PJ. Esophageal motor disorders in terms of high-resolution esophageal pressure topography: what has changed? Am J Gastroenterol 2010;105:981-987. https://doi.org/10.1038/ajg.2010.43
  • 37. Truong LD, Stroehlein JR, Mc Kechnie JC. Gastric heterotopia of the proximal esophagus and review of literature. Am J Gastroenterol 1986;81:1162-1166.
  • 38. Chong VH. Clinical significance of heterotopic gastric mucosal patch of the proximal esophagus. World J Gastroenterol 2013;19:331-338. https://doi.org/10.3748/wjg.v19.i3.331
  • 39. Von Rahden BH, Stein HJ, Becker K, Liebermann Meffert D, Siewert JR. Heterotopic gastric mucosa of the esophagusliteraturereview and proposal of a clinicopathologic classification. Am J Gastroenterol. 2004;99:543-551. https://doi.org/10.1111/j.1572-0241.2004.04082.x
  • 40. Liacouras CA, Furuta GT, Hirano I, et al. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol 2011;128:3-20. https://doi.org/10.1016/j.jaci.2011.02.040
  • 41. Dalby K, Nielsen RG, Kruse Andersen S, et al. Eosinophilic oesopha gitis in infants and children in the region of southern Denmarka prospective study of prevalence and clinical presentation. J Pediatr Gastroenterol Nutr 2010;51:280-282. https://doi.org/10.1097/MPG.0b013e3181d1b107
  • 42. Cheung KM, Oliver MR, Cameron DJ, Catto Smith AG, Chow CW. Esophageal eosinophilia in children with dysphagia. J Pediatr Gastroenterol Nutr 2003;37:498-503. https://doi.org/10.1097/00005176-200310000-00018
  • 43. Desai TK, Stecevis V, Chang CH, Goldstein NS, Badizadegan K, Furuta GT. Association of eosinophilic inflammation with esophageal food impaction in adults. Gastrointest Endosc 2005;61:795-801. https://doi.org/10.1016/s0016-5107(05)00313-5
  • 44. Guajardo JR, Plotnick LM, Fende JM, Collins MH, Putnam PE, Rohegberg ME. Eosinophil associated gastrointestinal disordersa world-wide-web based registry. J Pediatr 2002;141:576-581. https://doi.org/10.1067/mpd.2002.127663
  • 45. Prasad GA, Talley NJ, Romero Y, et al. Prevalence and predictive factors of eosinophilic esophagitis in patients presenting with dysphagia: a prospective study. Am J Gastroenterol 2007;102:2627-2632. https://doi.org/10.1111/j.1572-0241.2007.01512.x

Evaluation of children with dysfagia

Year 2024, Volume: 17 Issue: 2, 215 - 224, 01.04.2024
https://doi.org/10.31362/patd.1343219

Abstract

Purpose: Difficulty in swallowing; It is a symptom that occurs as a result of mechanical inhibition of the transfer of ingested food from the mouth to the stomach. It can be due to acute and chronic diseases. It is presented because of the limited number of studies comparing the characteristics of both types of oropharyngeal and esophageal dysphagia in healthy and chronically ill children in the pediatric population.
Materials and methods: 201 pediatric patients admitted with dysphagia between May 2019 and November 2020 were included. They were grouped according to the types of dysphagia.
Results: Group-1 consisted of 80 pediatric patients with oropharyngeal dysphagia, while group-2 consisted of 121 pediatric patients with esophageal dysphagia. 51.7% of the patients were female, mean age was 9.4 years. While all patients in Group-2 had solid food dysphagia, Group-1 had 27% liquid and 53% solid-liquid dysphagia. Percutaneous endoscopic gastrostomy tube for 50 pediatric patients who could not be fed safely; A nasogastric feeding tube was placed in 4 children. Esophagogastroduodenoscopy was performed in 72.6% of the patients, and esophageal pathology was detected in 55.4%.
Conclusions: Although the incidence of dysphagia is high in children with chronic diseases, it should not be forgotten that it can also be seen in healthy children and may be associated with treatable.

References

  • 1. Cho SY, Choung RS, Saito YA, et al. Prevalence and risk factors for dysphagia: a USA community study. Neurogastroenterol Motil 2015;27:212-219. https://doi.org/10.1111/nmo.12467
  • 2. Dodrill P, Gosa MM. Pediatric dysphagia: physiology, assessment, and management. Ann Nutr Metab 2015;66:24-31. https://doi.org/10.1159/000381372
  • 3. Kuo P, Holloway RH, Nguyen NQ. Current and future techniques in the evaluation of dysphagia. J Gastroenterol Hepatol 2012;27:873-881. https://doi.org/10.1111/j.1440-1746.2012.07097.x
  • 4. Bhattacharyya N. The prevalence of pediatric voice and swallowing problems in the United States. Laryngoscope 2015;125:746-750. https://doi.org/10.1002/lary.24931
  • 5. Manikam R, Perman JA. Pediatric feeding disorders. J Clin Gastroenterol 2000;30:34-46. https://doi.org/10.1097/00004836-200001000-00007
  • 6. Kakodkar K, James W. Schroeder Jr. Pediatric dysphagia. Pediatr Clin N Am 2013:60:969-977. http://dx.doi.org/10.1016/j.pcl.2013.04.010
  • 7. Arvedson JC. Assessment of pediatric dysphagia and feeding disorders: clinical and instrumental approaches. Dev Disabil Res Rev 2008;14:118-127. https://doi.org/10.1002/ddrr.17
  • 8. Svystun O, Johannsen W, Persad R, Turner JM, Majaesic C, El Hakim H. Dysphagia in healthy children characteristics and management of a consecutive cohort at a tertiary centre. Int J Pediatr Otorhinolaryngol 2017;99:54-59. https://doi.org/10.1016/j.ijporl.2017.05.024
  • 9. Lefton Greif MA, Okelo SO, Wright JM, Collaco JM, McGrath Morrow SA, Eakin MN. Impact of children's feeding/swallowing problems validation of a new caregiver instrument. Dysphagia 2014;29:671-677. https://doi.org/10.1007/s00455-014-9560-7
  • 10. Sheikh S, Allen E, Shell R, et al. Chronic aspiration without gastroesophageal reflux as a cause of chronic respiratory symptoms in neurologically normal infants. Chest 2001;120:1190-1195. https://doi.org/10.1378/chest.120.4.1190
  • 11. Duffy Kimberly LMA. Dysphagia in children. Curr Probl Pediatr Adolesc Health Care 2018;48:71-73. https://doi.org/10.1016/j.cppeds.2018.01.003
  • 12. Steele CM, Cichero JA. Physiological factors related to aspiration risk: a systematic review. Dysphagia 2014;29:295-304. https://doi.org/10.1007/s00455-014-9516-y
  • 13. Lefton Greif MA. Pediatric dysphagia. Phys Med Rehabil Clin N Am 2008;19:837-851. https://doi.org/10.1016/j.pmr.2008.05.007
  • 14. Lefton Greif MA, Carroll JL, Loughlin GM. Long-term follow-up of oropharyngeal dysphagia in children without apparent risk factors. Pediatr Pulmonol 2006;41:1040-1048. https://doi.org/10.1002/ppul.20488
  • 15. Hiorns MP, Ryan MM. Current practice in paediatric videofluoroscopy. Pediatric Radiology 2006;36:911-919. https://doi.org/10.1007/s00247-006-0124-3
  • 16. Benfer KA, Weir KA, Boyd RN. Clinimetrics of measures of oropharyngeal dysphagia for preschool children with cerebral palsy and neurodevelopmental disabilities a systematic review. Dev Med Child Neurol 2012;54:784-795. https://doi.org/10.1111/j.1469-8749.2012.04302.x
  • 17. Stabler SP, Allen RH, Savage DG. Lindenbaum J. Clinical spectrum and diagnosis of cobalamin deficiency. Blood 1990;76:871-881.
  • 18. Rasmussen SA, Fernhoff PM, Scanlon KS. Vitamin B12 deficiency in children and adolescents. J Pediatr 2001;138:10-17. https://doi.org/10.1067/mpd.2001.112160
  • 19. Lawlor CM, Choi S. Diagnosis and management of pediatric dysphagia a review. JAMA Otolaryngol Head Neck Surg 2020;146:183-191. https://doi.org/10.1001/jamaoto.2019.3622
  • 20. Godino J, Wong PW. A triad of troubling findings. Postgrad Med 2000;108:109-110. https://doi.org/10.3810/pgm.2000.08.1198
  • 21. Dantas RO, Villanova MG. Esophageal motility impairment Plummer-Vinson syndrome. Correction by iron treatment. Dig Dis Sci 1993;38:968-971. https://doi.org/10.1007/BF01295930
  • 22. Novacek G. Plummer-Vinson syndrome. Orphanet J Rare Dis 2006;1:36. https://doi.org/10.1186/1750-1172-1-36 23. Schatzki R. The lower esophageal ring. Long term follow-up of symptomatic and asymptomatic rings. Am J Roentgenol Radium Ther Nucl Med 1963;90:805-810.
  • 24. Müller M, Gockel I, Hedwig P, et al. Is the Schatzki ring a unique esophageal entity? World J Gastroenterol 2011;17:2838-2843. https://doi.org/10.3748/wjg.v17.i23.2838
  • 25. Akın M. Schatzki’s ring (Lower esophageal mucosal ring). Turkiye Klinikleri J Gen Surg Special Topics 2012;5:116-120.
  • 26. Mutaf O. Caustic esophageal burns in children. Journal of Pediatric Surgery 1988;2:69-85.
  • 27. Moulin D, Bertrand JM, Buts JP, Nyakabasa M, Otte JB. Upper airvay lesions in children after accidental ingestion of caustic substances. J Pediatr 1985;106:408-410. https://doi.org/10.1016/s0022-3476(85)80665-x
  • 28. Kutlu T, Çullu F, Erkan T, Aji D, Tümay G.T. Korozif madde içen çocukların değerlendirilmesi. Türk Pediatri Arşivi 1998;33:92-98.
  • 29. Previtera C, Giusti F, Guglielmi M. Predictive value of visible lesions (cheeks, lips, oropharynx)in suspected caustic ingestion may endoscopy reasonably be omitted in completely negative pediatric patients? Pediatr Emerg Care 1990;6:176-178. https://doi.org/10.1097/00006565-199009000-00002
  • 30. Zaninotto G, Bennett C, Boeckxstaens G, et al. The 2018 ISDE achalasia guidelines. Diseases of the Esophagus 2018;31:1-29. https://doi.org/10.1093/dote/doy071
  • 31. Huoha KC, Messner AH. Cricopharyngeal achalasia in children indications for treatment and management options. Curr Opin Otolaryngol Head Neck Surg 2013;21:576-580. https://doi.org/10.1097/01.moo.0000436789.29814.62
  • 32. Franklin AL, Petrosyan M, Kane TD. Childhood achalasia acomprehensive review of disease, diagnosis and therapeutic management. World J Gastrointest Endosc 2014;6:105-111. https://doi.org/10.4253/wjge.v6.i4.105
  • 33. Domingues GR, Lemme EM. Differential diagnosis of esophageal motor disorders based in characteristics of dysphagia. Arq Gastroenterol 2001;38:14-18. https://doi.org/10.1590/s0004-28032001000100004
  • 34. Zhang Y, Xu CD, Zaouche A, Cai W. Diagnosis and management of esophageal achalasia in children: analysis of 13 cases. World J Pediatr 2009;5:56-59. https://doi.org/10.1007/s12519-009-0010-9
  • 35. Hussain SZ, Thomas R, Tolia V. A review of achalasia in 33 children. Dig Dis Sci 2002;47:2538-2543. https://doi.org/10.1023/a:1020572328777
  • 36. Kahrilas PJ. Esophageal motor disorders in terms of high-resolution esophageal pressure topography: what has changed? Am J Gastroenterol 2010;105:981-987. https://doi.org/10.1038/ajg.2010.43
  • 37. Truong LD, Stroehlein JR, Mc Kechnie JC. Gastric heterotopia of the proximal esophagus and review of literature. Am J Gastroenterol 1986;81:1162-1166.
  • 38. Chong VH. Clinical significance of heterotopic gastric mucosal patch of the proximal esophagus. World J Gastroenterol 2013;19:331-338. https://doi.org/10.3748/wjg.v19.i3.331
  • 39. Von Rahden BH, Stein HJ, Becker K, Liebermann Meffert D, Siewert JR. Heterotopic gastric mucosa of the esophagusliteraturereview and proposal of a clinicopathologic classification. Am J Gastroenterol. 2004;99:543-551. https://doi.org/10.1111/j.1572-0241.2004.04082.x
  • 40. Liacouras CA, Furuta GT, Hirano I, et al. Eosinophilic esophagitis: updated consensus recommendations for children and adults. J Allergy Clin Immunol 2011;128:3-20. https://doi.org/10.1016/j.jaci.2011.02.040
  • 41. Dalby K, Nielsen RG, Kruse Andersen S, et al. Eosinophilic oesopha gitis in infants and children in the region of southern Denmarka prospective study of prevalence and clinical presentation. J Pediatr Gastroenterol Nutr 2010;51:280-282. https://doi.org/10.1097/MPG.0b013e3181d1b107
  • 42. Cheung KM, Oliver MR, Cameron DJ, Catto Smith AG, Chow CW. Esophageal eosinophilia in children with dysphagia. J Pediatr Gastroenterol Nutr 2003;37:498-503. https://doi.org/10.1097/00005176-200310000-00018
  • 43. Desai TK, Stecevis V, Chang CH, Goldstein NS, Badizadegan K, Furuta GT. Association of eosinophilic inflammation with esophageal food impaction in adults. Gastrointest Endosc 2005;61:795-801. https://doi.org/10.1016/s0016-5107(05)00313-5
  • 44. Guajardo JR, Plotnick LM, Fende JM, Collins MH, Putnam PE, Rohegberg ME. Eosinophil associated gastrointestinal disordersa world-wide-web based registry. J Pediatr 2002;141:576-581. https://doi.org/10.1067/mpd.2002.127663
  • 45. Prasad GA, Talley NJ, Romero Y, et al. Prevalence and predictive factors of eosinophilic esophagitis in patients presenting with dysphagia: a prospective study. Am J Gastroenterol 2007;102:2627-2632. https://doi.org/10.1111/j.1572-0241.2007.01512.x
There are 44 citations in total.

Details

Primary Language English
Subjects Gastroenterology and Hepatology
Journal Section Research Article
Authors

Sevinç Garip 0000-0002-2512-6924

Early Pub Date December 25, 2023
Publication Date April 1, 2024
Submission Date August 15, 2023
Acceptance Date December 12, 2023
Published in Issue Year 2024 Volume: 17 Issue: 2

Cite

AMA Garip S. Evaluation of children with dysfagia. Pam Med J. April 2024;17(2):215-224. doi:10.31362/patd.1343219

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