Investigation of the Relationship between Antioxidant Levels and Body Mass Index and Obesity

Year 2025, Volume: 5 Issue: 2, 46 - 50, 25.07.2025

Elif Zeynep Öztürk , Fatmagül Düzenli , Neslihan Yüce , Mehlika Alataş , İlayda Havuz , Ufuk Uzun , Özgür Araz , Nurcan Kılıç Baygutalp

https://doi.org/10.62425/pharmata.1541951

Abstract

Objective: Today, it is well known that obesity plays a role in the pathogenesis of many diseases, and one of these mechanisms of action is oxidative stress. There are many studies on the formation of oxidative stress in obesity, but its effect on young adults (18-35 years old) is not fully known.
Method: In this context, we investigated oxidative stress levels by measuring oxidant (MDA) and antioxidant (SOD) parameters in young adult obese and overweight individuals with ELISA method. Our hypothesis is that the oxidant parameter (MDA) is high and the antioxidant parameter (SOD) is low in young adult obese individuals due to oxidative stress.
Results: According to the study results, a statistically significant difference was found in the SOD and MDA values ​​of overweight individuals (p<0.001) and a statistical difference was found in the SOD and MDA values ​​of obese individuals (p<0.05). According to the results of our study, oxidative stress is high not only in obese but also in overweight individuals. In fact, a higher rate of oxidative stress was observed in overweight individuals compared to obese individuals.
Conclusion: These data show us the importance of weight control in preventing the development of diseases by preventing the formation of oxidative stress. With further research, the effect of oxidative stress in young individuals will be understood more clearly.

Keywords

MDA , Obesity , Overweight , Oxidative Stress , SOD

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