Prognostic Value of SCUBE-1 in Ischemic Stroke

Year 2023, , 123 - 123, 01.07.2023

İbrahim Altunok

https://doi.org/10.38175/phnx.1251231

Abstract

SCUBE-1 is a newly identified cell surface protein identified during early embryogenesis. SCUBE-1 is known to be involved in the angiogenesis mechanism. SCUBE-1 was first detected in human umbilical vein endothelial cells, so it was said that it originates and is secreted from the vascular endothelium. It is also found in organs and tissues with high vascularization such as kidney, brain, lung, spleen and liver

Keywords

SCUBE-1, Stroke, Emergency medicine

SCUBE-1 in İskemik İnmede Prognostik Değeri

Abstract

SCUBE-1, erken embriyogenez sırasında tanımlanan yeni tanımlanmış bir hücre yüzeyi proteinidir. SCUBE-1'in anjiyogenez mekanizmasında etkili olduğu bilinmektedir. SCUBE-1 ilk olarak insan ublikal arter endotel hücrelerinde tespit edildi, bu nedenle damar endotelinden kaynaklandığı ve salgılandığı söylendi. Ayrıca böbrek, beyin, akciğer, dalak ve karaciğer gibi damarlanması yüksek organ ve dokularda bulunur.

Keywords

SCUBE-1, İnme, Acil tıp

References

• REFERENCES Sonmez E, Turkdogan KA, Karabacak M, Civelek C, Yilmaz C, Ozer OF, et al. The diagnostic role of signal peptide-C1r/C1s, Uegf, and Bmp1-epidermal growth factor domain-containing protein 1 in non-ST-elevation acute coronary syndrome. Am J Emerg Med. 2015 Jan;33(1):21-4.
• Özkan A, Sönmez E, Özdemir S, Özer ÖF, Muharrem N, Gülen B, et al. The Diagnostic Value of SCUBE1 in Unstable Angina Pectoris Patients. Eurasian J Emerg Med. 2016;15:167-171.
• Yılmaz C, Gülen B, Sönmez E, Akbay D, Söğüt Ö, Özdemir S, et al. Serum SCUBE-1 Levels and Return of Spontaneous Circulation Following Cardiopulmonary Resuscitation in Adult Patients. Avicenna J Med. 2022 Sep 5;12(3):148-153.
• Özdemir S, Cimilli Öztürk T, Ecmel Onur Ö. Relationship between the national institutes health stroke scale score and bispectral index in patients with acute ischemic stroke. J Exp Clin Med. 2021; 38(4): 440-4.
• Santomauro DF, Melen S, Mitchison D, Vos T, Whiteford H, Ferrari AJ. The hidden burden of eating disorders: an extension of estimates from the Global Burden of Disease Study 2019. Lancet Psychiatry. 2021 Apr;8(4):320-328.
• Yigit M, Sogut O, Yigit E, Turkdogan KA, Kaplan O, Dur A, et al. The relationship between anemia and recurrence of ischemic stroke in patients with Trousseau’s syndrome: A retrospective cross-sectional study. Turk J Emerg Med. 2016 May 9;16(2):65-68.
• Dai DF, Thajeb P, Tu CF, Chiang FT, Chen CH, Yang RB, et al. Plasma concentration of SCUBE1, a novel platelet protein, is elevated in patients with acute coronary syndrome and ischemic stroke. J Am Coll Cardiol. 2008 Jun 3;51(22):2173-80.
• Turkmen S, Eryigit U, Karaca Y, Mentese A, Sumer UA, Yulug E, et al. Diagnostic value of plasma signal peptide-Cub-Egf domain-containing protein-1 (SCUBE-1) in an experimental model of acute ischemic stroke. Am J Emerg Med. 2015 Feb;33(2):262-5.
• Bolayır A, Gökçe ŞF, Çiğdem B, Bolayır HA, Gülünay A, Çelik VK, et al. Can SCUBE1 be used to predict the early diagnosis, lesion volume and prognosis of acute ischemic stroke? Turk J Biochem. 2018;44:16-24.