Paracetamol Poisoning

Year 2025, Volume: 7 Issue: 3, 123 - 123, 13.01.2026

Alp Batuhan Öztürk

Abstract

Different treatment and follow-up protocols have been established for patients presenting to the emergency department with paracetamol overdose in different clinical scenarios. Within 24 hours, in cases of acute overdose where the time and amount of ingestion are known, the blood acetaminophen level is measured and the antidote is started based on the risk of liver damage estimated according to the revised Rumack-Matthew curve. In cases where the ingestion history is uncertain, in cases of delayed presentation, and in cases where laboratory values are inconsistent with the history, the acetylcysteine protocol is recommended.

Keywords

Paracetamol , Toxicology , Acetylcysteine

Parasetamol Zehirlenmeleri

Abstract

Parasetamol fazla alımıyla acil servise başvuran hastalar için farklı klinik senaryolarda farklı tedavi ve takip protokolleri oluşturulmuştur. 24 saat içerisinde Akut alım durumunda alım zamanı ve miktarı net şekilde biliniyorsa kan asetaminofen düzeyi ölçülerek revize Rumack-Matthew eğrisine göre karaciğer hasarı gelişim riski tahmin edilerek antidotu başlanır. Alım öyküsü şüpheli olan durumlarda, geç başvuru durumlarında ve öyküyle uyumsuz laboratuvar değerleri bulunması durumunda ise asetilsistein protokolü uygulanması önerilir.

Keywords

parasetamol , toksikoloji , asetilsistein

References

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