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Corpus Callosum Infarction: Case Presentation

Year 2026, Volume: 8 Issue: 1 , 40 - 42 , 31.03.2026
https://izlik.org/JA58DJ83BA

Abstract

The commissural fiber bundle connecting the two hemispheres of the brain is called the corpus callosum (CC). It plays a fundamental role in integrating sensory, motor, and cognitive information from homologous areas of association in the brain hemispheres. Anatomically, it is divided into four parts: rostrum, genu, body, and splenium. Ischemic infarction of the CC is rare. The main risk factors include hypertension, diabetes, atrial fibrillation, smoking, hyperlipidemia, low activity level, obesity, family history of stroke, history of cerebral infarction, coronary heart disease, chronic renal failure, and long-term alcohol use. CC involvement is not disease-specific. Clinical features are generally non-specific. They include headache, limb weakness, movement disorders, memory impairment, rarely foreign hand syndrome, and classic callosal linkage syndrome. Therefore, it can easily be overlooked and misdiagnosed in the early stages. For this purpose; We wanted to present a 33-year-old male patient with acute heart attack who presented with nausea, vomiting, headache, dizziness, and unsteady hand and arm movements, but had a normal neurological examination and was conscious.

References

  • Shin HW, Song SK, Sohn YH. Is progressive upper-body apraxia a corticobasal syndrome? J Clin Neurosci 2013;20(2):319-22.
  • Nakamura T, Fujishima I. Usefulness of ice massage in triggering the swallow reflex. J Stroke Cerebrovasc Dis 2013;22(4):378-82.
  • Murthy SB, Chmayssani M, Shah S, Goldsmith CE, Kass JS. Clinical and radiologic spectrum of corpus callosum infarctions: clues to the etiology. J Clin Neurosci 2013;20(1):175-7.
  • Ishizaki M, Ueyama H, Nishida Y, Imamura S, Hirano T, Uchino M. Crossed aphasia following an infarction in the right corpus callosum. Clin Neurol Neurosurg 2012;114(2):161-5.
  • Aloumanis KP, Papapetrou PD. Corpus callosum aplasia in a young patient with a parathyroid adenoma. J Clin Neurosci 2007;14(11):1124-6.
  • Hofer S, Frahm J. Topography of the human corpus callosum revisited—comprehensive fiber tractography using diffusion tensor magnetic resonance imaging. Neuroimage 2006;32(3):989-94.
  • Li S, Sun X, Bai YM, Qin HM, Wu XM, Zhang X, et al. Infarction of the corpus callosum: a retrospective clinical investigation. PLoS One 2015;10(3):e0120409.
  • Saito Y, Matsumura K, Shimizu T. Anterograde amnesia associated with infarction of the anterior fornix and genu of the corpus callosum. J Stroke Cerebrovasc Dis 2006;15(4):176-7.
  • Yang LL, Huang YN, Cui ZT. Clinical features of acute corpus callosum infarction patients. Int J Clin Exp Pathol 2014;7(8):5160-5.
  • Sun X, Li J, Fan C, Zhang H, Si Y, Fang X, et al. Clinical, neuroimaging and prognostic study of 127 cases with infarction of the corpus callosum. Eur J Neurol 2019;26(8):1075-81.
  • Kasow DL, Destian S, Braun C, Quintas JC, Kagetsu NJ, Johnson CE. Corpus callosum infarcts with atypical clinical and radiologic presentations. AJNR Am J Neuroradiol 2000;21(10):1876-80.
  • Wu F, Leong C, Su T. Alien hand syndrome: report of two cases. Chang Gung Med J 1999;22(4):660-5.
  • Yu M, Zhang Y, Li Y, Li M, Li W, Zhang J, et al. Splenial lesions of the corpus callosum: disease spectrum and MRI findings. Korean J Radiol 2017;18(4):710-21.
  • Unterberger I, Bauer R, Walser G, Bauer G. Corpus callosum and epilepsies. Seizure 2016;37:55-60.
  • Tada H, Takanashi J, Barkovich AJ, Oba H, Maeda M, Tsukahara H, et al. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology 2004;63(10):1854-8.
  • Kim YD, Lee ES, Lee KS, Kim JS. Callosal alien hand sign following a right parietal lobe infarction. J Clin Neurosci 2010;17(6):796-7.
  • Al-Hashim AH, Blaser S, Raybaud C, MacGregor D. Corpus callosum abnormalities: neuroradiological and clinical correlations. Dev Med Child Neurol 2016;58(5):475-84.
  • Güven H, Delibaş Ş, Comoğlu SS. Transient lesion in the splenium of the corpus callosum due to carbamazepine. Turk Neurosurg 2008;18(3):309-12.
  • Yuan JL, Wang SK, Guo XJ, Hu WL. Acute infarct of the corpus callosum presenting as alien hand syndrome: evidence of diffusion-weighted imaging and magnetic resonance angiography. BMC Neurol 2011;11:142.

Korpus Kallozum Enfarktı: Olgu Sunumu

Year 2026, Volume: 8 Issue: 1 , 40 - 42 , 31.03.2026
https://izlik.org/JA58DJ83BA

Abstract

Her iki beyin yarımküresini birbirine bağlayan komissural lif demetine korpus kallozum (KK) denir. Beyin yarımkürelerindeki homolog ilişki alanlarından gelen duyusal, motor ve bilişsel bilgileri bütünleştirmede temel rol oynar. Anatomik rostrum, genu, gövde ve splenium olarak dört bölüme ayrılır. KK iskemik enfarktüsü nadirdir. Başlıca risk faktörleri hipertansiyon, diyabet, atriyal fibrilasyon, sigara kullanımı, hiperlipidemi, düşük aktivite, obezite, ailede inme öyküsü, serebral enfarktüs öyküsü, koroner kalp hastalığı, kronik böbrek yetmezliği ve uzun süreli alkol kullanımı mevcuttur. KK tutulumu bir hastalığa özgü değildir. Klinik özellikler genellikle spesifik değildir. Baş ağrısı, uzuv zayıflığı, hareket bozuklukları, hafıza bozukluğu, nadiren yabancı el sendromu ve klasik kallozal bağlantı kopma sendromunu içerir. Bu nedenle erken evrede kolayca gözden kaçabilir ve yanlış tanı alabilir. Bu amaçla; bulantı, kusma, baş ağrısı, baş dönmesi, dengesiz el ve kol hareketleri bulunan, nörolojik muayenesi normal ve bilinci açık olan 33 yaşında, akut KK enfarktüsü gelişmiş erkek hastayı sunmak istedik.

Ethical Statement

Olgu sunumu olduğu için etik kurul onayı gerekli değildi.

Supporting Institution

yok

Thanks

yok

References

  • Shin HW, Song SK, Sohn YH. Is progressive upper-body apraxia a corticobasal syndrome? J Clin Neurosci 2013;20(2):319-22.
  • Nakamura T, Fujishima I. Usefulness of ice massage in triggering the swallow reflex. J Stroke Cerebrovasc Dis 2013;22(4):378-82.
  • Murthy SB, Chmayssani M, Shah S, Goldsmith CE, Kass JS. Clinical and radiologic spectrum of corpus callosum infarctions: clues to the etiology. J Clin Neurosci 2013;20(1):175-7.
  • Ishizaki M, Ueyama H, Nishida Y, Imamura S, Hirano T, Uchino M. Crossed aphasia following an infarction in the right corpus callosum. Clin Neurol Neurosurg 2012;114(2):161-5.
  • Aloumanis KP, Papapetrou PD. Corpus callosum aplasia in a young patient with a parathyroid adenoma. J Clin Neurosci 2007;14(11):1124-6.
  • Hofer S, Frahm J. Topography of the human corpus callosum revisited—comprehensive fiber tractography using diffusion tensor magnetic resonance imaging. Neuroimage 2006;32(3):989-94.
  • Li S, Sun X, Bai YM, Qin HM, Wu XM, Zhang X, et al. Infarction of the corpus callosum: a retrospective clinical investigation. PLoS One 2015;10(3):e0120409.
  • Saito Y, Matsumura K, Shimizu T. Anterograde amnesia associated with infarction of the anterior fornix and genu of the corpus callosum. J Stroke Cerebrovasc Dis 2006;15(4):176-7.
  • Yang LL, Huang YN, Cui ZT. Clinical features of acute corpus callosum infarction patients. Int J Clin Exp Pathol 2014;7(8):5160-5.
  • Sun X, Li J, Fan C, Zhang H, Si Y, Fang X, et al. Clinical, neuroimaging and prognostic study of 127 cases with infarction of the corpus callosum. Eur J Neurol 2019;26(8):1075-81.
  • Kasow DL, Destian S, Braun C, Quintas JC, Kagetsu NJ, Johnson CE. Corpus callosum infarcts with atypical clinical and radiologic presentations. AJNR Am J Neuroradiol 2000;21(10):1876-80.
  • Wu F, Leong C, Su T. Alien hand syndrome: report of two cases. Chang Gung Med J 1999;22(4):660-5.
  • Yu M, Zhang Y, Li Y, Li M, Li W, Zhang J, et al. Splenial lesions of the corpus callosum: disease spectrum and MRI findings. Korean J Radiol 2017;18(4):710-21.
  • Unterberger I, Bauer R, Walser G, Bauer G. Corpus callosum and epilepsies. Seizure 2016;37:55-60.
  • Tada H, Takanashi J, Barkovich AJ, Oba H, Maeda M, Tsukahara H, et al. Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology 2004;63(10):1854-8.
  • Kim YD, Lee ES, Lee KS, Kim JS. Callosal alien hand sign following a right parietal lobe infarction. J Clin Neurosci 2010;17(6):796-7.
  • Al-Hashim AH, Blaser S, Raybaud C, MacGregor D. Corpus callosum abnormalities: neuroradiological and clinical correlations. Dev Med Child Neurol 2016;58(5):475-84.
  • Güven H, Delibaş Ş, Comoğlu SS. Transient lesion in the splenium of the corpus callosum due to carbamazepine. Turk Neurosurg 2008;18(3):309-12.
  • Yuan JL, Wang SK, Guo XJ, Hu WL. Acute infarct of the corpus callosum presenting as alien hand syndrome: evidence of diffusion-weighted imaging and magnetic resonance angiography. BMC Neurol 2011;11:142.
There are 19 citations in total.

Details

Primary Language Turkish
Subjects Emergency Medicine
Journal Section Other
Authors

Müslime Kasa 0000-0002-1202-9471

Submission Date February 19, 2026
Acceptance Date February 26, 2026
Publication Date March 31, 2026
IZ https://izlik.org/JA58DJ83BA
Published in Issue Year 2026 Volume: 8 Issue: 1

Cite

Vancouver 1.Müslime Kasa. Korpus Kallozum Enfarktı: Olgu Sunumu. Phnx Med J. [Internet]. 2026 Mar. 1;8(1):40-2. Available from: https://izlik.org/JA58DJ83BA

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