Fluoxetine-Induced Reversible Galactorrhea and Hyperprolactinemia: A Case Report

Abstract

Selective serotonin reuptake inhibitors can lead to increased prolactin levels and galactorrhea. Herein, we reported a 40-year-old female patient who developed galactorrhea and hyperprolactinemia two weeks after initiation of fluoxetine 20 mg/day. Galactorrhea was discontinued after the fifth week of fluoxetine withdrawal and prolactin levels reached normal limits. The patient's depressive symptoms disappeared with citalopram 40 mg/day and no similar side effects were observed during follow-up. Clinicians should be aware of the hyperprolactinemia and galactorrhea adverse effects of fluoxetine.

Keywords

• fluoxetine
• galactorrhea
• prolactin
• hyperprolactinemia

Fluoksetine Bağlı Geri Dönüşümlü Galaktore ve Hiperprolaktinemi: Bir Olgu Sunumu

Abstract

Seçici serotonin geri alım inhibitörleri prolactin düzeyi yükselmesine ve galaktoreye yol açabilir. Burada, 20 mg/gün fluoksetin tedavisine başlandıktan iki hafta sonra galaktore ve hiperprolaktinemi gelişen 40 yaşında bir kadın hastayı sunduk. Fluoksetin kesilmesinin beşinci haftasından sonra galaktore kesildi ve prolaktin seviyeleri normal sınırlara ulaştı. Hastanın depresif semptomları sitalopram 40 mg/gün ile ortadan kalktı ve takipte benzer yan etkilere rastlanmadı. Klinisyenler, fluoksetinin hiperprolaktinemi ve galaktore yan etkilerine karşı uyanık olmalıdır.

Keywords

• fluoksetin
• galaktore
• prolaktin
• hiperprolaktinemi

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