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THE RELATIONSHIP BETWEEN LUNG INVOLVEMENT LEVEL AND LABORATORY PARAMETERS IN COVID-19 PCR-POSITIVE PATIENTS

Cilt: 1 Sayı: 3 30 Eylül 2024
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THE RELATIONSHIP BETWEEN LUNG INVOLVEMENT LEVEL AND LABORATORY PARAMETERS IN COVID-19 PCR-POSITIVE PATIENTS

Abstract

Objectives: The aim of our study is to examine the relationship between the level of uptake of the planet with cell Covid-19 PCR positivity and laboratory data in the Covid emergency polyclinic of the X University Training and Research Hospital. Materials and Methods: Data from 224 Covid-19 PCR positive patients who applied to the Covid emergency outpatient clinic of X University Training and Research Hospital between March 2021 and September 2021, whose thoracic CT was taken and laboratory parameters were studied, were used. Results: Of the 224 patients who participated in the study, 52.2% (n=117) were female patients, and 63.8% (n=143) were patients between the ages of 18-64. The CORADS classification of 53.6% (n=120) of the patients was 5-6 on thorax CT. As the lymphocyte level in the blood decreased, lung involvement increased on CT (p<0.004). As CRP, LDH, and fibrinogen levels in the blood increased, lung involvement increased (p<0.001). As the neutrophil/lymphocyte ratio, LDH/lymphocyte ratio and Platelet/lymphocyte ratio increased, uptake in CT increased (p<0.001, p<0.001 and p<0.002, respectively). As the lymphocyte/CRP ratio decreased, CT uptake increased (p<0.001). Conclusion: Our study revealed that the increase in blood parameters such as lymphopenia, CRP, LDH, and fibrinogen increases lung involvement and increases hospitalization and intensive care unit admission. It should be kept in mind that lymphocyte, CRP, LDH and hematological rates, which are measured by investigating biochemical blood parameters in clinics where imaging is not possible, may be associated with lung involvement and prognosis of Covid-19 infection.

Keywords

Kaynakça

  1. Yang X, Yu Y, Xu J, et al. (2020). Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Resp Med, in press. Liu K, Fang Y-Y, Deng Y, et al. (2020). Clinical characteristics of novel coronavirus cases in tertiary hospitals in Hubei Province. Chin Med J, in press. Bohn M.K, Lippi G, Horvath A, et al., Molecular, serological, and biochemical diagnosis and monitoring of COVID-19: IFCC taskforce evaluation of the latest evidence, Clinical Chemistry and Laboratory Medicine, 2020; 58: 1037–1052 Altmayer S, Zanon M, Pacini GS, et al. Comparison of the computed tomography findings in COVID-19 and other viral pneumonia in immunocompetent adults: A systematic review and meta-analysis. Eur Radiol 2020; 30: 6485-6496.

Ayrıntılar

Birincil Dil

İngilizce

Konular

İç Hastalıkları , Klinik Tıp Bilimleri (Diğer)

Bölüm

Araştırma Makalesi

Yayımlanma Tarihi

30 Eylül 2024

Gönderilme Tarihi

7 Ağustos 2024

Kabul Tarihi

26 Eylül 2024

Yayımlandığı Sayı

Yıl 2024 Cilt: 1 Sayı: 3

Kaynak Göster

Vancouver
1.Merve Altıntop, Kerem Uzun, Büşra Usluoğlu, Aslıhan Aşkın, Serdar Karakullukçu, Cuneyt Ardıç. THE RELATIONSHIP BETWEEN LUNG INVOLVEMENT LEVEL AND LABORATORY PARAMETERS IN COVID-19 PCR-POSITIVE PATIENTS. RMJ [Internet]. 01 Eylül 2024;1(3):1-15. Erişim adresi: https://izlik.org/JA75CY82ZD

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