Kanser Tedavisinde İmmunoterapi ve Radyoterapi

Year 2021, Volume: 1 Issue: 1, 16 - 27, 28.06.2021

Sema Rakici

Abstract

Kanser tedavisinde immunoterapi son zamanlarda ön plana çıkmış olsa da, immün sisteminin kanser oluşumu önlenmesindeki rolü uzun zamandır bilinmektedir. İmmunoterapinin mevcut standart tedavilerle kombine edilmesi konusundaki çalışmalar yüz yıldan fazladır gündemdedir. Kanseri tedavi edenler artan hasta sayısı, uzun kontrol ve takip süreçleri ile bir
kanserle yaşayan hastalarına iyi tedavi ve iyi bir yaşam kalitesinden yararlanacak tüm şeyleri onlara sunmalıdır. Bu anlamda son araştırmalar da dikkate alındığında radyoterapi ve immünoterapi kombinasyonu (radyoimmünoterapi), birçok farklı kanser türünde tedavi yanıtını iyileştirmek için cazip bir olasılık olarak görünmektedir.
Kişinin kendi bağışıklık sisteminin gücünü, özgünlüğünü ve doğasını kullanarak, kansere karşı bağışıklık sisteminin güçlendirilebildiği bilinmektedir. Böylece immünoterapi, kanseri tedavi etmede çok güçlü araçlar sağlayabileceğinin keşfi ile zaten kanser tedavisinin kutsalları
arasında yer almaya başladı. Artık yapılması gereken, immunoterapinin mekanizmalarını anlamaya çalışarak onu radyoterapi dahil kanserin tüm klasik silahları ile kombine etme stratejileri geliştirmek olmalıdır.

Keywords

İmmünoterapi, bağışıklık kontrol noktaları, immün sürveyans, kanser, radyoterapi, radyoimmünoterapi, abskopal etki, Immunotherapy, immune checkpoints, immune surveillance, cancer, radiotherapy, radioimmunotherapy, abscopal effect

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