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Unraveling the Complexity of Drug-Induced Pancreatitis: Mechanisms, Risks, and Management

Year 2023, Volume: 1 Issue: 4, 1 - 5, 30.12.2023

Abstract

This article explores the complexity of drug-induced pancreatitis, a form of pancreatitis triggered by medications. It emphasizes potential connections between drugs such as azathioprine, valproic acid, and specific antiretroviral agents and pancreatitis. The etiology of drug-induced pancreatitis is shaped by multiple factors, including direct cellular injury, immune response, and genetic predisposition. Challenges in diagnosis and management, as well as future research areas, are also addressed.

References

  • 1. Sarı S ve Sarı MC. (2023). Sitagliptin Kullanımına Bağlı Tekrarlayan Akut Pankreatit: Olgu Sunumu. RMJ;1(3):35-6.
  • 2. Özdemir S, Altunok ˙I ve Algın A. (2023) Relationship of the systemic immuno-inflammation index and hematological inflammatory index with mortality and hospitalization in acute pancreatitis: a cross-sectional study. Front Emerg Med.;7(2): e13.
  • 3. Altunok İ ve Özdemir S. (2022) Relationship Between Platelet Indices and Prolonged Hospitalization in Patients with Acute Pancreatitis: A Retrospective Observational Study. J Contemp Med. September;12(5):743-748. doi:10.16899/jcm.1131462
  • 4. Akoglu EU, Özdemir S, Ak R ve Ozturk TC. (2021) The Discriminative Power of Inflammatory Markers in Patients with Mild-To-Moderate Acute Pancreatitis: Mean Platelet Volume, Neutrophil-Lymphocyte Ratio, Lymphocyte-Monocyte Ratio, and Neutrophil-Monocyte Product. South Clin Ist Euras;32(2):159-64.
  • 5. İslam MM, Osoydan Satıcı M, Ademoğlu E, Erdil FN, Odabaşı T, Eker A., … Eroglu SE. (2023). The role of delta neutrophil index in early identification of severe acute pancreatitis in adult patients: a prospective diagnostic accuracy study. Med Sci Discov.;10(7):487-94.
  • 6. Kokulu K, Günaydın YK, Akıllı NB, Köylü R, Sert ET, Köylü Ö ve Cander B. (2018). Relationship between the neutrophil-tolymphocyte ratio in acute pancreatitis and the severity and systemic complications of the disease. Turk J Gastroenterol.;29(6):684-91.
  • 7. Jones MR, Hall OM, Kaye AM ve Kaye AD. (2015). Drug-induced acute pancreatitis: a review. Ochsner J. Spring;15(1):45-51.
  • 8. Yanar F, Agcaoglu O, Sarici IS, Ozcinar B, Gok AF, Gunay K ve Ertekin C. (2013). Clinical challenges in drug induced pancreatitis: Presentation of two cases and review of the literature. Int J Surg Case Rep.;4(8):708-10.

İlaçlara Bağlı Pankreatitin Karmaşıklığını Çözümlemek: Mekanizmalar, Riskler ve Yönetim

Year 2023, Volume: 1 Issue: 4, 1 - 5, 30.12.2023

Abstract

References

  • 1. Sarı S ve Sarı MC. (2023). Sitagliptin Kullanımına Bağlı Tekrarlayan Akut Pankreatit: Olgu Sunumu. RMJ;1(3):35-6.
  • 2. Özdemir S, Altunok ˙I ve Algın A. (2023) Relationship of the systemic immuno-inflammation index and hematological inflammatory index with mortality and hospitalization in acute pancreatitis: a cross-sectional study. Front Emerg Med.;7(2): e13.
  • 3. Altunok İ ve Özdemir S. (2022) Relationship Between Platelet Indices and Prolonged Hospitalization in Patients with Acute Pancreatitis: A Retrospective Observational Study. J Contemp Med. September;12(5):743-748. doi:10.16899/jcm.1131462
  • 4. Akoglu EU, Özdemir S, Ak R ve Ozturk TC. (2021) The Discriminative Power of Inflammatory Markers in Patients with Mild-To-Moderate Acute Pancreatitis: Mean Platelet Volume, Neutrophil-Lymphocyte Ratio, Lymphocyte-Monocyte Ratio, and Neutrophil-Monocyte Product. South Clin Ist Euras;32(2):159-64.
  • 5. İslam MM, Osoydan Satıcı M, Ademoğlu E, Erdil FN, Odabaşı T, Eker A., … Eroglu SE. (2023). The role of delta neutrophil index in early identification of severe acute pancreatitis in adult patients: a prospective diagnostic accuracy study. Med Sci Discov.;10(7):487-94.
  • 6. Kokulu K, Günaydın YK, Akıllı NB, Köylü R, Sert ET, Köylü Ö ve Cander B. (2018). Relationship between the neutrophil-tolymphocyte ratio in acute pancreatitis and the severity and systemic complications of the disease. Turk J Gastroenterol.;29(6):684-91.
  • 7. Jones MR, Hall OM, Kaye AM ve Kaye AD. (2015). Drug-induced acute pancreatitis: a review. Ochsner J. Spring;15(1):45-51.
  • 8. Yanar F, Agcaoglu O, Sarici IS, Ozcinar B, Gok AF, Gunay K ve Ertekin C. (2013). Clinical challenges in drug induced pancreatitis: Presentation of two cases and review of the literature. Int J Surg Case Rep.;4(8):708-10.
There are 8 citations in total.

Details

Primary Language English
Subjects Clinical Sciences (Other)
Journal Section Editöre Mektup
Authors

Serdar Özdemir

Publication Date December 30, 2023
Submission Date December 10, 2023
Acceptance Date December 28, 2023
Published in Issue Year 2023 Volume: 1 Issue: 4

Cite

Vancouver Özdemir S. Unraveling the Complexity of Drug-Induced Pancreatitis: Mechanisms, Risks, and Management. RMJ. 2023;1(4):1-5.

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