COVID-19 and Hemoglobinopathies

Abstract

The novel coronavirus disease (COVID-19) was firstly reported at the end of 2019. The disease rapidly spread all around the world in a few months and was declared a worldwide pandemic by World Health Organisation in March 2020. COVID-19 causes respiratory tract illness that may generally occur as mild upper respiratory tract disease or pneumonia. Older patients and those with pre-existing medical conditions such as hypertension, diabetes, cardiovascular disease, cancer, chronic lung disease and chronic kidney disease have been identified as populations at risk of a severe disease course. Therefore, it is not clear how COVID-19 will progress in hemoglobinopathies such as sickle cell anemia and thalassemia, which are common comorbidity. In this review, it is planned to examine the condition of COVID-19, in which we still have limited information and remains unknown, in sickle cell anemia and thalassemia patients.

Keywords

• COVID-19,thalassemia,sickle cell disease

COVID-19 ve Hemoglobinopatiler

Abstract

Yeni koronavirüs hastalığı (COVID-19) ilk olarak 2019'un sonunda bildirildi. Hastalık birkaç ay içinde hızla tüm dünyaya yayıldı ve Mart 2020'de Dünya Sağlık Örgütü tarafından dünya çapında bir salgın olarak ilan edildi. COVID-19 üst solunum yolu enfeksiyonu veya pnömoni gibi solunum yolu enfeksiyonlarına neden olan bir hastalıktır. İleri yaş grubunda ve altta yatan hipertansiyon, diabet, kardiyovasküler hastalık, kanser, kronik akciğer hastalığı, ve kronik böbrek hastalığı gibi komorbiditesi olanlar ağır hastalık tablosu için risk oluşturmaktadır. Bu yüzden orak hücreli anemi ve talasemi gibi sık komorbidite görülen hemoglobinopatilerde COVID-19'un nasıl seyredeceği net olarak bilinmemektedir. Bu derlemede halen kısıtlı bilgilere ulaşabildiğimiz ve bilinmezliği devam eden COVID-19’un orak hücreli anemi ve talasemi hastalarındaki durumunun irdelenmesi amaçlanmıştır.

Keywords

• COVID-19,talasemi,orak hücreli anemi,hemoglobinopati

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