BibTex RIS Cite

Non-steroidal anti-inflammatory drug supplementation modulates lipid peroxidation and total antioxidant levels in serum of patients with primary dysmenorrhea

Year 2013, Volume: 5 Issue: 3, 245 - 251, 01.09.2013

Abstract

Dysmenorrhea is a common painful gynecological disorder in young women during menstrual cycle. Inflammation and oxidative toxicity were reported in the patients with primary dysmenorrhea although its etiology is still unclear. We investigated effects of non-steroidal anti-inflammatory drug (NSAID) supplementation on lipid peroxidation, total antioxidant status (TAS) and antioxidant vitamin values in serum of patients with primary dysmenorrhea.

We used three groups in this study. First group was used as control. Second group constituted patients (primary dysmenorrhea) group. Third group was daily received oral NSAID for 6 weeks before blood serum taken. 

The lipid peroxidation level was higher in patient group than in control although its level was lower in treatment group than in control group. The TAS concentrations were lower in patients group than in control. However, TAS and vitamin C concentrations were higher in treatment group than in patient group. Serum vitamin A, vitamin E and -carotene concentrations did not differ in the three groups.

In conclusion, we observed that women with primary dysmenorrhea are a consideration with increased oxidative stress in serum. The NSAID supplementation in serum of women may strengthen the antioxidant defense system by decreasing oxidative stress.


Year 2013, Volume: 5 Issue: 3, 245 - 251, 01.09.2013

Abstract

There are 0 citations in total.

Details

Journal Section Original Articles
Authors

Mustafa Nazıroğlu

Mehmet Güney This is me

Önder Kaplan

Publication Date September 1, 2013
Published in Issue Year 2013 Volume: 5 Issue: 3

Cite

APA Nazıroğlu, M., Güney, M., & Kaplan, Ö. (2013). Non-steroidal anti-inflammatory drug supplementation modulates lipid peroxidation and total antioxidant levels in serum of patients with primary dysmenorrhea. Cell Membranes and Free Radical Research, 5(3), 245-251.
AMA Nazıroğlu M, Güney M, Kaplan Ö. Non-steroidal anti-inflammatory drug supplementation modulates lipid peroxidation and total antioxidant levels in serum of patients with primary dysmenorrhea. Cell Membranes and Free Radical Research. September 2013;5(3):245-251.
Chicago Nazıroğlu, Mustafa, Mehmet Güney, and Önder Kaplan. “Non-Steroidal Anti-Inflammatory Drug Supplementation Modulates Lipid Peroxidation and Total Antioxidant Levels in Serum of Patients With Primary Dysmenorrhea”. Cell Membranes and Free Radical Research 5, no. 3 (September 2013): 245-51.
EndNote Nazıroğlu M, Güney M, Kaplan Ö (September 1, 2013) Non-steroidal anti-inflammatory drug supplementation modulates lipid peroxidation and total antioxidant levels in serum of patients with primary dysmenorrhea. Cell Membranes and Free Radical Research 5 3 245–251.
IEEE M. Nazıroğlu, M. Güney, and Ö. Kaplan, “Non-steroidal anti-inflammatory drug supplementation modulates lipid peroxidation and total antioxidant levels in serum of patients with primary dysmenorrhea”, Cell Membranes and Free Radical Research, vol. 5, no. 3, pp. 245–251, 2013.
ISNAD Nazıroğlu, Mustafa et al. “Non-Steroidal Anti-Inflammatory Drug Supplementation Modulates Lipid Peroxidation and Total Antioxidant Levels in Serum of Patients With Primary Dysmenorrhea”. Cell Membranes and Free Radical Research 5/3 (September 2013), 245-251.
JAMA Nazıroğlu M, Güney M, Kaplan Ö. Non-steroidal anti-inflammatory drug supplementation modulates lipid peroxidation and total antioxidant levels in serum of patients with primary dysmenorrhea. Cell Membranes and Free Radical Research. 2013;5:245–251.
MLA Nazıroğlu, Mustafa et al. “Non-Steroidal Anti-Inflammatory Drug Supplementation Modulates Lipid Peroxidation and Total Antioxidant Levels in Serum of Patients With Primary Dysmenorrhea”. Cell Membranes and Free Radical Research, vol. 5, no. 3, 2013, pp. 245-51.
Vancouver Nazıroğlu M, Güney M, Kaplan Ö. Non-steroidal anti-inflammatory drug supplementation modulates lipid peroxidation and total antioxidant levels in serum of patients with primary dysmenorrhea. Cell Membranes and Free Radical Research. 2013;5(3):245-51.