INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM

Nil Erge Akkaya; Sevim Iscı Turutoglu; A. Fatih Ertem; Zeynep Kalaycıoglu; Fatemeh Bahadorı; Huceste Catalgıl Gız

INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM

Abstract

Curcumin is a natural bioactive material which has very low water solubility. In this work, solubility of curcumin was increased with a natural edible linear polysaccharide, alginate, in ultrasound medium at 25oC. Curcumin solubility in alginate-water solution (2% by weight) was increased up to 1.525 ×10-3 M at pH 7 and up to 0.317 ×10-3 M at pH 2.4. The critical aggregate concentration of alginate for curcumin-alginate complexes, were determined as 1 % (by weight). The sizes and surface charges of curcumin-alginate complexes were measured. Nano sized complexes with a uniform size distribution were obtained. Antioxidant capacities of the complexes were determined by 2, 2-Diphenyl-1-picrylhydrazyl and Folin- Ciocalteu methods. For both methods, the antioxidant capacities of complexes were higher than that of curcumin itself. Complexes were stable at all dilutions with water and can be considered as candidate materials for food and drug preparations.

Keywords

References

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Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Nil Erge Akkaya This is me
0000-0003-4775-198X
Türkiye

Sevim Iscı Turutoglu This is me
0000-0002-6049-5397
Türkiye

A. Fatih Ertem This is me
0000-0003-4392-7132
Türkiye

Zeynep Kalaycıoglu This is me
0000-0002-0967-0997
Türkiye

Fatemeh Bahadorı This is me
0000-0003-4224-9309
Türkiye

Huceste Catalgıl Gız This is me
0000-0001-7674-4186
Türkiye

Publication Date

March 1, 2019

Submission Date

October 6, 2018

Acceptance Date

November 3, 2018

Published in Issue

Year 2019 Volume: 37 Number: 1

IZ

https://izlik.org/JA43MG77XW

Cite

RIS / Bibtex

APA

Akkaya, N. E., Iscı Turutoglu, S., Ertem, A. F., Kalaycıoglu, Z., Bahadorı, F., & Catalgıl Gız, H. (2019). INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM. Sigma Journal of Engineering and Natural Sciences, 37(1), 85-92. https://izlik.org/JA43MG77XW

AMA

1.Akkaya NE, Iscı Turutoglu S, Ertem AF, Kalaycıoglu Z, Bahadorı F, Catalgıl Gız H. INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM. SIGMA. 2019;37(1):85-92. https://izlik.org/JA43MG77XW

Chicago

Akkaya, Nil Erge, Sevim Iscı Turutoglu, A. Fatih Ertem, Zeynep Kalaycıoglu, Fatemeh Bahadorı, and Huceste Catalgıl Gız. 2019. “INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM”. Sigma Journal of Engineering and Natural Sciences 37 (1): 85-92. https://izlik.org/JA43MG77XW.

EndNote

Akkaya NE, Iscı Turutoglu S, Ertem AF, Kalaycıoglu Z, Bahadorı F, Catalgıl Gız H (March 1, 2019) INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM. Sigma Journal of Engineering and Natural Sciences 37 1 85–92.

IEEE

[1]N. E. Akkaya, S. Iscı Turutoglu, A. F. Ertem, Z. Kalaycıoglu, F. Bahadorı, and H. Catalgıl Gız, “INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM”, SIGMA, vol. 37, no. 1, pp. 85–92, Mar. 2019, [Online]. Available: https://izlik.org/JA43MG77XW

ISNAD

Akkaya, Nil Erge - Iscı Turutoglu, Sevim - Ertem, A. Fatih - Kalaycıoglu, Zeynep - Bahadorı, Fatemeh - Catalgıl Gız, Huceste. “INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM”. Sigma Journal of Engineering and Natural Sciences 37/1 (March 1, 2019): 85-92. https://izlik.org/JA43MG77XW.

JAMA

1.Akkaya NE, Iscı Turutoglu S, Ertem AF, Kalaycıoglu Z, Bahadorı F, Catalgıl Gız H. INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM. SIGMA. 2019;37:85–92.

MLA

Akkaya, Nil Erge, et al. “INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM”. Sigma Journal of Engineering and Natural Sciences, vol. 37, no. 1, Mar. 2019, pp. 85-92, https://izlik.org/JA43MG77XW.

Vancouver

1.Nil Erge Akkaya, Sevim Iscı Turutoglu, A. Fatih Ertem, Zeynep Kalaycıoglu, Fatemeh Bahadorı, Huceste Catalgıl Gız. INCREASING THE WATER SOLUBILITY OF CURCUMIN, BY ALGINATE IN ULTRASOUND MEDIUM. SIGMA [Internet]. 2019 Mar. 1;37(1):85-92. Available from: https://izlik.org/JA43MG77XW