Research Article

SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS

Volume: 33 Number: 1 March 1, 2015
  • Sevil Yücel
  • Pınar Terzioğlu
  • Zeynep Aydın Sinirlioğlu
  • Bilge Sema Tekerek
  • Yeliz Başaran Elalmış

SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS

Abstract

The purpose of this study was to synthesize strontium substituted melt derived 45S5 bioactive glasses by use of rice hull ash silica and commercial silica. The degradation behaviour of bioactive glass samples was studied through the weight loss in the tris-(hydroxymethyl)-aminomethane solution. The in vitro bioactivity of the bioactive glass samples was evaluated by soaking studies in simulated body fluid. The apatite like layer formation on glasses surface was assessed by X-ray powder diffraction, scanning electron microscope, inductively coupled plasma and Vickers hardness measurement analyses. Also, the effect of bioactive glass samples on osteoblasts in vitro and cell mineralisation was investigated. The present investigation revealed that both of the samples show similar bioactivity but 45S5 bioactive glass from rice hull ash silica supported cell activity better than commercial silica. Thus, rice hull ash silica can be used to synthesize strontium substituted 45S5 bioactive glasses and it is also good alternative to commercial silica.

Keywords

References

  1. [1] Gentleman E., Fredholm Y.C., Jell G., et.al., “The effects of strontium-substituted bioactive glasses on osteoblasts and osteoclasts in vitro”, Biomaterials, 31, 3949–3956, 2010.
  2. [2] Tsigkou O., Jones J.R., Polak J.M., et.al., “Differentiation of fetal osteoblasts and formation of mineralized bone nodules by 45S5 bioglass conditioned medium in the absence of osteogenic supplements”, Biomaterials, 30,21, 3542–3550,2009.
  3. [3] Hench L.L., Thompson I., “Twenty-first century challenges for Biomaterials”, J. R. Soc. Interface, 7, 379–391, 2010.
  4. [4] Goel A., Rajagopal R.R., Ferreira J.M.F., “Influence of strontium on structure, sinteringandbiodegradationbehaviourof CaO–MgO–SrO–SiO2–P2O5–CaF2 glasses”, ActaBiomaterialia, 7, 4071–4080, 2011.
  5. [5] Usuda K., Kono K., Dote T., et.al., “An overview of boron, lithium, andstrontium in humanhealth andprofiles of theseelements in urine of Japanese”, EnvironHealthPrevMed, 12, 6, 231–237, 2007.
  6. [6] Fredholm Y.C., Karpukhina N., Law R.V., et.al., “Strontium containing bioactive glasses: Glass structure and physical properties”, J Non-Cryst Solids, 356,2546–2551, 2010.
  7. [7] Oudadesse H., Dietrich E., Bui X.V., et.al., “Enhancement of cells proliferation and control of bioactivity of strontium doped glass”, Applied Surface Science, 257, 8587– 8593, 2011.
  8. [8] Gorustovich A.A., Steimetz T., Cabrini R.L., et.al., “Osteoconductivity of strontium-doped bioactive glass particles: a histomorphometric study in rats”, J Biomed Mater Res A, 92A, 1, 232-237, 2010.

Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Sevil Yücel This is me
Türkiye

Pınar Terzioğlu This is me
Türkiye

Zeynep Aydın Sinirlioğlu This is me
Türkiye

Bilge Sema Tekerek This is me
Türkiye

Yeliz Başaran Elalmış This is me
Türkiye

Publication Date

March 1, 2015

Submission Date

November 10, 2014

Acceptance Date

November 24, 2014

Published in Issue

Year 2015 Volume: 33 Number: 1

APA
Yücel, S., Terzioğlu, P., Aydın Sinirlioğlu, Z., Tekerek, B. S., & Başaran Elalmış, Y. (2015). SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS. Sigma Journal of Engineering and Natural Sciences, 33(1), 23-32. https://izlik.org/JA32KT57GE
AMA
1.Yücel S, Terzioğlu P, Aydın Sinirlioğlu Z, Tekerek BS, Başaran Elalmış Y. SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS. SIGMA. 2015;33(1):23-32. https://izlik.org/JA32KT57GE
Chicago
Yücel, Sevil, Pınar Terzioğlu, Zeynep Aydın Sinirlioğlu, Bilge Sema Tekerek, and Yeliz Başaran Elalmış. 2015. “SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS”. Sigma Journal of Engineering and Natural Sciences 33 (1): 23-32. https://izlik.org/JA32KT57GE.
EndNote
Yücel S, Terzioğlu P, Aydın Sinirlioğlu Z, Tekerek BS, Başaran Elalmış Y (March 1, 2015) SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS. Sigma Journal of Engineering and Natural Sciences 33 1 23–32.
IEEE
[1]S. Yücel, P. Terzioğlu, Z. Aydın Sinirlioğlu, B. S. Tekerek, and Y. Başaran Elalmış, “SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS”, SIGMA, vol. 33, no. 1, pp. 23–32, Mar. 2015, [Online]. Available: https://izlik.org/JA32KT57GE
ISNAD
Yücel, Sevil - Terzioğlu, Pınar - Aydın Sinirlioğlu, Zeynep - Tekerek, Bilge Sema - Başaran Elalmış, Yeliz. “SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS”. Sigma Journal of Engineering and Natural Sciences 33/1 (March 1, 2015): 23-32. https://izlik.org/JA32KT57GE.
JAMA
1.Yücel S, Terzioğlu P, Aydın Sinirlioğlu Z, Tekerek BS, Başaran Elalmış Y. SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS. SIGMA. 2015;33:23–32.
MLA
Yücel, Sevil, et al. “SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS”. Sigma Journal of Engineering and Natural Sciences, vol. 33, no. 1, Mar. 2015, pp. 23-32, https://izlik.org/JA32KT57GE.
Vancouver
1.Sevil Yücel, Pınar Terzioğlu, Zeynep Aydın Sinirlioğlu, Bilge Sema Tekerek, Yeliz Başaran Elalmış. SYNTHESIS, CHARACTERIZATION, IN VITRO DEGRADABILITY AND BIOACTIVITY OF STRONTIUM SUBSTITUTED RICE HULL ASH SILICA BASED MELT DERIVED 45S5 BIOACTIVE GLASS. SIGMA [Internet]. 2015 Mar. 1;33(1):23-32. Available from: https://izlik.org/JA32KT57GE

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