Research Article

ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE

Volume: 34 Number: 3 September 1, 2016
  • Burcu Tuncer
  • Banu Mansuroğlu
  • Serap Derman

ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE

Abstract

Flavonoids are polyphenols compounds a structural class of mainly natural and a products of secondary metabolism of plants. Flavonoids, which can be found in herbs and trees, act as natural chemopreventives and anticancer agents [1]. As natural products, they have major importance for human life and also have a widespread effect such as antioxidant, antinflammatory, anticarcinogen, antidiabetic [2, 3]. However, bioavailability of this polyphenolic antioxidant have limited because of their high water solubility [4], low absorption, permeability, stability, slow dissolution rate, and light-induced decomposition over time in the physiological medium. In recent years, various methods have been tried to overcome the limitations of flavonoids, including its incorporation into micels and nanoparticles.

Keywords

References

  1. [1] Papademetrio, D.L., et al., The catechin flavonoid reduces proliferation and induces apoptosis of murine lymphoma cells LB02 through modulation of antiapoptotic proteins. Revista Brasileira de Farmacognosia, 2013. 23(3): p. 455-463.
  2. [2] Middleton, E., C. Kandaswami, and T.C. Theoharides, The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. Pharmacological reviews, 2000. 52(4): p. 673-751.
  3. [3] Sporn, M.B. and N. Suh, Chemoprevention: an essential approach to controlling cancer. Nature Reviews Cancer, 2002. 2(7): p. 537-543.
  4. [4] Aditya, N., et al., Co-delivery of hydrophobic curcumin and hydrophilic catechin by a water-in-oil-in-water double emulsion. Food chemistry, 2015. 173: p. 7-13.
  5. [5] Srivastava, A.K., et al., Synthesis of PLGA nanoparticles of tea polyphenols and their strong in vivo protective effect against chemically induced DNA damage. International journal of nanomedicine, 2013. 8: p. 1451.
  6. [6] Bhardwaj, P. and D. Khanna, Green tea catechins: defensive role in cardiovascular disorders. Chinese journal of natural medicines, 2013. 11(4): p. 345-353.
  7. [7] Zanwar, A., et al., Antioxidant role of catechin in health and disease. Polyphenols in Human Health and Disease; Watson, RR, Preedy, VR, Eds, 2014: p. 267-271.
  8. [8] Velayutham, P., A. Babu, and D. Liu, Green tea catechins and cardiovascular health: an update. Current medicinal chemistry, 2008. 15(18): p. 1840.

Details

Primary Language

English

Subjects

Engineering

Journal Section

Research Article

Authors

Burcu Tuncer This is me
Türkiye

Banu Mansuroğlu This is me
Türkiye

Serap Derman This is me
Türkiye

Publication Date

September 1, 2016

Submission Date

May 18, 2016

Acceptance Date

August 1, 2016

Published in Issue

Year 2016 Volume: 34 Number: 3

APA
Tuncer, B., Mansuroğlu, B., & Derman, S. (2016). ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE. Sigma Journal of Engineering and Natural Sciences, 34(3), 453-465. https://izlik.org/JA88AJ85BY
AMA
1.Tuncer B, Mansuroğlu B, Derman S. ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE. SIGMA. 2016;34(3):453-465. https://izlik.org/JA88AJ85BY
Chicago
Tuncer, Burcu, Banu Mansuroğlu, and Serap Derman. 2016. “ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE”. Sigma Journal of Engineering and Natural Sciences 34 (3): 453-65. https://izlik.org/JA88AJ85BY.
EndNote
Tuncer B, Mansuroğlu B, Derman S (September 1, 2016) ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE. Sigma Journal of Engineering and Natural Sciences 34 3 453–465.
IEEE
[1]B. Tuncer, B. Mansuroğlu, and S. Derman, “ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE”, SIGMA, vol. 34, no. 3, pp. 453–465, Sept. 2016, [Online]. Available: https://izlik.org/JA88AJ85BY
ISNAD
Tuncer, Burcu - Mansuroğlu, Banu - Derman, Serap. “ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE”. Sigma Journal of Engineering and Natural Sciences 34/3 (September 1, 2016): 453-465. https://izlik.org/JA88AJ85BY.
JAMA
1.Tuncer B, Mansuroğlu B, Derman S. ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE. SIGMA. 2016;34:453–465.
MLA
Tuncer, Burcu, et al. “ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE”. Sigma Journal of Engineering and Natural Sciences, vol. 34, no. 3, Sept. 2016, pp. 453-65, https://izlik.org/JA88AJ85BY.
Vancouver
1.Burcu Tuncer, Banu Mansuroğlu, Serap Derman. ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE. SIGMA [Internet]. 2016 Sep. 1;34(3):453-65. Available from: https://izlik.org/JA88AJ85BY

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