ANTIOXIDANT EFFECT OF CATECHIN LOADED POLYMERIC NANOPARTICLE

Year 2016, Volume: 34 Issue: 3, 453 - 465, 01.09.2016

Burcu Tuncer Banu Mansuroğlu Serap Derman

Abstract

Flavonoids are polyphenols compounds a structural class of mainly natural and a products of secondary metabolism of plants. Flavonoids, which can be found in herbs and trees, act as natural chemopreventives and anticancer agents [1]. As natural products, they have major importance for human life and also have a widespread effect such as antioxidant, antinflammatory, anticarcinogen, antidiabetic [2, 3]. However, bioavailability of this polyphenolic antioxidant have limited because of their high water solubility [4], low absorption, permeability, stability, slow dissolution rate, and light-induced decomposition over time in the physiological medium. In recent years, various methods have been tried to overcome the limitations of flavonoids, including its incorporation into micels and nanoparticles.

Keywords

Nanoparticle, catechin, antioxidant activity, polymeric nanoparticle

References

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