Parkinson Hastalarında Akupunktur Tedavisinin Etkinliğinin Değerlendirilmesi

Abstract

Amaç: Akupunktur, Parkinson Hastalığı (PH) tedavisinde en yaygın kullanılan tamamlayıcı tedavi yöntemidir. Bu çalışmada, erken evre Parkinson hastalarında akupunktur tedavisinin etkinliğini değerlendirmeyi amaçladık. Yöntem: 29 Parkinson hastası, akupunktur (n=17) ve kontrol grubu (n=12) olmak üzere iki gruba rastgele dağıtıldı. Çalışmanın birincil sonuç ölçütü, temel alınan verilere göre 5. hafta sonunda Birleşik Parkinson Hastalığı Derecelendirme Ölçeği (UPDRS) skorlarındaki değişim idi. İkincil sonuç ölçütleri, uyku eğilimi ve yaşam kalitesini değerlendirmek için kullanılan Epworth Uykululuk Ölçeği (ESS) ve Kısa Form-36 Sağlık Durumu Anketi (SF-36) skorlarının 5 hafta sonraki değişimiydi. Bulgular: Akupunktur grubunda, tedavi sonrasında UPDRS, ESS ve SF-36'nın fiziksel fonksiyon ve ağrı boyutu skorlarında iyileşme gözlendi (p<0,05). Akupunktur grubunda tedavi öncesi ve sonrası UPDRS-toplam ve UPDRS I-III skorlarındaki değişimin, kontrol grubuna göre istatistiksel olarak anlamlı derecede daha yüksek olduğu belirlendi (etki büyüklüğü 0,76; 0,57; 0,91; 0,94 sırasıyla, p<0,001). Sonuç: Çalışmamız, akupunktur tedavisinin farmakolojik tedavi ile birleştirilerek semptomları ve yaşam kalitesini iyileştirmede sadece farmakolojik tedaviye göre daha etkili bir tedavi yaklaşımı olarak kullanılabileceğine dair kanıt sunmaktadır.

Keywords

• Parkinson Hastalığı
• Akupunktur
• Birleşik Parkinson Hastalığı Derecelendirme Ölçeği
• Epworth Uykululuk Ölçeği
• Kısa Form 36 Sağlık Durumu Anketi

Evaluation of the Effectiveness of Acupuncture Treatment in Patients with Parkinson’s Disease

Abstract

Objectives: Acupuncture is the most widely used complementary therapy management for the treatment of Parkinson's Disease (PD). We aimed to evaluate the effectiveness of acupuncture treatment in early-stage Parkinson's patients. Method: 29 Parkinson's patients were randomized into two groups as acupuncture (n=17) and control groups (n=12). The primary outcome measure of the study was the change from baseline to the 5th week in the Unified Parkinson’s Disease Rating Scale (UPDRS) scores. Secondary outcome measures are the change in Epworth Sleepiness Scale (ESS) and Short Form-36 (SF-36) scores, which are used to evaluate sleep propensity and quality of life, at 5 weeks. Results: Improvement was found in the UPDRS, ESS, and SF-36 physical function and pain dimension scores after treatment in the acupuncture group (p<0.05). It was determined that the change in the UPDRS-total and UPDRSI-III scores before and after the treatment in the acupuncture group was statistically significantly higher than the control group (effect size 0.76; 0.57; 0.91; 0.94 respectively, p<0.001). Conclusion: Our study provides evidence that combined acupuncture treatment with pharmacological treatment can be used as a more effective treatment approach in improving symptoms and quality of life than pharmacological treatment alone.

Keywords

• Parkinson's disease
• Acupuncture
• Unified Parkinson’s Disease Rating Scale
• Epworth Sleepiness Scale
• Short Form 36 Health Status Questionnaire

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