Kırım Kongo Kanamalı Ateşinden Korunma

Abstract

Kırım Kongo Kanamalı Ateşi (KKKA), eski Sovyetler Birliğinde ilk kez 1944’te Kırımda 200’ün üzerinde kişiyi etkileyen büyük bir salgın esnasında tanımlandı. KKKA hastalığının etkeni olan KKKA virüsü, Bunyaviridae ailesinin Nairovirus grubuna ait bir RNA virüsüdür. KKKA keneyle bulaşan bir hastalıktır ayrıca insandan insana enfekte vücut sıvılarına temasla geçiş olabilmektedir. KKKA virüsü hayvanlarda yaygın bir coğrafik dağılım göstermesine rağmen nadiren insan hastalığı olarak tanımlanmaktadır. Hastalık için tarım çalışanları ve hayvancılık ile uğraşanlar ile endemik bölgelerde görev yapan sağlık personeli yüksek risklidir. KKKA Afrika, Orta Doğu, Avrupa ve Batı Asya’yı içine alan dünyanın birçok bölgesinde görülen bir halk sağlığı sorunudur.

Keywords

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Prevent From Crimean-Congo Hemorrhagic Fever

Abstract

Crimean-Congo Hemorrhagic Fever (CCHF)was first clinically described in 1944 in Crimeaof the former Soviet Union during a large outbreak of over 200 cases.CCHF virus is a RNA virus, the agent ofCCHF,which is a member of the Nairovirus genus of the family Bunyaviridae. CCHF is a tickborne disease that may also be transmittedthrough person-to-person transmission by exposure to infected body fluids. Despite its widegeographic distribution in animals, CCHF virusis rarely associated with recognized human diseases. Agricultural workers, animal raisers andhealthcare personnel working in endemic regions are at high risk for the disease.CCHF is a public health problem in many regions of the world, including Africa, MiddleEast, Europe and Western Asia.

Keywords

• Crimean-Congo Hemorrhagic Fever, prevention

References

1. Bakir M,Ugurlu M,Dokuzoguz B,et al,Turkish CCHF Study Group. Crimean-Congo Hemorrhagic Fever outbreak in Middle Anatolia;a multicenter study of clinical features and outcome measures,J Med Microbial 2005;54:385-9.
2. Bozkurt G.Y,Memikoğlu K.O,Azap A ve ark, Kırım Kongo kanamalı ateşi: Olgu sunumu, Ankara Üniversitesi Tıp Fakülfesi Mecmuası,2005;58:193-196.
3. Burt FJ, Spencer DC, Leman PA, et al. Investigation of tick-borne viruses as pathogens of humans in So- uth Africa and evidence of Dugbe virus infection in a patient with prolonged thrombocytopenia. Epide- miol Infect. 1996; 116: 353 – 61.
4. Burt FJ, Swanepoel R, Shieh WJ, et al. Immunohistoche- mical and in situ localization of Crimean-Congo he- morrhagic fever (CCHF) virus in human tissues and implications for CCHF pathogenesis. Arch Pathol Lab Med. 1997. 121: 839–846.
5. Capua I, Crimean Congo Hemorrhagic fever in ostric- hes:A public health risk for countries of the Europe- an Union?Avian pathology,1998;27:117-20.
6. Casals J., 1969, Antigenic similarity between the virus causing Crimean Hemorrhagic Fever, Soc. Exp.Bi- ol.Med.131:233-236.
7. CDC. Update: Management of patients with suspected viral hemorrhagic fever - United States. MMWR 1995;44:475-79.
8. CDC.Management of patients with suspected viral he- morrhagic fever, MMWR 1988;37:1-16.

9. CDC.Update:Outbreak of Ebola Viral Hemorrhagic fever- Zaire,MMWR 1995;44(25):468-469.
10. Chapman L.E, Wilson ML, Hall DB,et al,Risk factors for Crimean Congo Hemorrhagic fever rural Northern Senegal J.Infect.Dis.1991,164:686-692.
11. Chinikar S. The specific serological investigation of suspected human and animals to have Crimean- Congo hemorrhagic fever in various parts of Iran using ELISA. Hakim. 2002; 4: 294-300.
12. CIDRAP:Viral Hemorrhagic Fever (VHF): Current, comprehensive information on pathogenesis, mic- robiology, epidemiology, diagnosis, treatment, and prophylaxis Last updated May 2, 2006.
13. Elaldı N, Kırım Kongo hemorajik ateş epidemiyoloji- si,C.Ü. Tıp Fakültesi Dergisi,2004,26(4):185-190.
14. El-Azazy OM, Scrimgeour EM. Crimean-Congo ha- emorrhagic fever virus infection in the western pro- vince of Saudi Arabia. Trans R Soc Trop Med Hyg 1997. 91: 275–278.
15. Ergonul O, Celikbas A,Dokuzoguz B et al, Characteris- tic of patients with Crimean-Congo Hemorrhagic Fever in a recent outbreak in Turkey and impact of oral ribavirin therapy.CID 2004;39:284-7.
16. Fisher-Hoch SP, McCormick JB, Swanepoel R, et al. Risk of human infections with Crimean Congo He- morrhagic fever in a South African rural community. Am J Trop Med Hyg,1992;47:337-45.
17. Fisher-Hoch SP, Price ME, Craven RB, Price FM, Fort- hall DN, Sasso DR, Scott SM, McCormick JB. Sa- fe intensive-care management of a severe case of Lassa fever with simple barrier nursing techniques. 1985.Lancet 2: 1227–1229.
18. Fisher-Hoch SP, Tomori O, et al. Review of cases of no- socomial Lassa fever in Nigeria: the high price of poor medical practice. BMJ 1995;311(7009):857-9.
19. Flick R, Whitehouse CA. Crimean-Congo hemorrhagic fever virus. Curr Mol Med. 2005;5(8):753-60.
20. Goldfarb LG,Chumakov MP,Myskin AA,et al.An epide- miological model of Crimean-Congo Hemorrhagic Fever. Am J Trop.Med Hyg,1980;92:260-4.
21. Gozalan A,Akin L,Rolain JM,et al.Epidemiological eva- luation of a possible outbreak in and near by Tokat province.Mikrobiyol Bul2004;38:33-44.
22. Guimard Y, Bwaka MA, Colebunders R, et al. Organiza- tion of patient care during the Ebola hemorrhagic fever epidemic in Kikwit, Democratic Republic of the Congo. 1995. J Infect Dis 1999 Feb:179(Suppl 1): S268-S273.
23. Hoogstraal H. The Epidemiology of tick-borne Crime- an-Congo Hemorrhagic Fever in Asia Europa and Africa J. Med. Entomol 1979;15:307, 417.
24. http://entomology.ucdavis.edu/fculty/rbkmsey/tick- bio.html, Haziran 2006.
25. http://www.medimagazin.com.tr/haber_38518.html. Haziran 2006.
26. http://www.ntvmsnbc.com/news/377663.asp) 22 Hazi- ran 2006.
27. http://www.turkei.net/Saglik/3311.html 29 Haziran 2006.
28. http://www.haber7.com/haber.php?haber_id=171190, Temmuz 2006.
29. Izadi S, Naieni K.H, Madjdzadeh S.R, et al,Crimean- Congo hemorrhagic fever in Sistan and Baluches- tan Province of Iran, a case-control study on epide- miological characteristics.Int J Infect Dis. 2004;8:299-306.
30. Jauréguiberry S, Tattevin P,Tarantola A, Imported Cri- mean-Congo Hemorrhagic Fever,Journal of Clini- cal Microbiology,2005;Vol. 43: No. 9,4905-4907
31. Karti SS,Odabaşı Z,Korten V,et al, Crimean-Congo He- morrhagic Fever in Turkey,Emerging infectious di- sease,2004,Vol:10,No:8,1379-84.
32. Khan AS, Maupin GO, Rollin PE, et al, 1997. An outb- reak of Crimean-Congo hemorrhagic fever in the United Arab Emirates, 1994–1995. Am J Trop Med Hyg 57: 519-525.
33. Nabeth P,D,Cheikh,B Lo, et all, Crimean Congo He- morrhagic Fever, Mauritania Emerging infectious disseases 2004,Vol:10,No:12,2143-49.
34. Naini R.A, Moghtaderi A, Koohpayeh HR et all, Crime- an Congo Hemorrhagic Fever ın southheasth of Iran, Journal of infection, 2006,52,378-382.
35. Simpson DIH Viral Hemorrhagic Fever of man Bull Wld Hltl Org 1978;56:819-32.
36. Smego RA,Sarwari A.R, ,Siddiqui A.R 2004 Crimean Congo Hemorrhagic fever control limitations in a resource poor country.Clin.İnfect.Dis.38:1731-35.
37. Swanepoel R,Shepherd AJ,Leman PA,et al, Acommon source outbrek of Crimean-Congo hemorrhagic fe- ver on a diary farm,S Afr. Med. J,1985;68:635-7.
38. Tavana AM,Sadegh C,Mazaheri V,The seroepidemiolo- gical aspects of Crimean-Congo Hemorrhagic Fe- ver in three health workers:a report from Iran, Arch Iranian Med 2002; 5 (4):255 – 258.
39. Todorov S,Kovacheva T, Veleheva D, et all, Congo Cri- mean Hemorrhagic Fever-prophlaxis and treat- ment,Contemporary Medicine,2001;42:54,-60
40. Whitehouse C.A. 2004 Crimean-Congo Hemorrhagic Fever. Antivir. Res. 64:145.
41. Williams RJ, Al-Busaidy S, Mehta FR, et al, Crimean Congo Hemorrhagic Fever: a Seroepidemiological and Tick Survey in the Sultanete of Oman.Trop med.int.health,2000:5;96-106.
42. Wilson ML, LeGuenna B, Guillaud M, et al, Crimean Congo Hemorrhagic fever viral antibody in Sene- gal: environmental, Trop.med.hyg,1990,43:557- 566.
43. Wirtz A,Niedrig M,Fock R, Management of patients in Germany with suspected viral haemorrhagic fever and other potentially lethal contagious infections, Euro Surveill 2002;7(3):36-42
44. World Health Organization. Fact sheet No, 208. 2001. Avalable at: http:/www.who.int/inf- fs/en/fact208Htm/.
45. www.ism.gov.tr/indir/KIRIMKONGO.ppt Haziran 2006
46. Zeller HG,Cornet JP,Diop A,et al, Crimean-Congo He- morrhagic Fever in ticks (acari:Ixoididae) and rumi- nants:field observations of an epizoitic in Ban- dia,Senegal(1989-1992) J Med Entemol 1997;34:511-6.