Research Article
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Year 2024, , 20 - 27, 30.08.2024
https://doi.org/10.55895/sshs.1427187

Abstract

References

  • Alvim, M. M., Silva, L. A. D., Leite, I. C. G., & Silvério, M. S. (2015). Adverse events caused by potential drug-drug interactions in an intensive care unit of a teaching hospital. Revista Brasileira de terapia intensiva, 27, 353-359.
  • Andrade, P. H. S., Santos, A. D. S., Souza, C. A. S., Lobo, I. M. F., & da Silva, W. B. (2017). Risk factors for adverse drug reactions in pediatric inpatients: a systematic review. Therapeutic advances in drug safety, 8(6), 199-210.
  • Antimicrobial Resistance Polict Insight. Accessed December 24, 2023. Retrieved from: https://www.oecd.org/health/health-systems/AMR-Policy-Insights November2016.pdf
  • Bhat, G. M. N., Holla, R., & Kamath P. S. D. (2015). A study of prescription pattern in the drug therapy of ear, nose, and throat infections at a tertiary care hospital in Mangalore. International Journal of Basic & Clinical Pharmacology, 4(4), 686–90.
  • Bindu, S., Mazumder, S., & Bandyopadhyay, U. (2020). Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective. Biochemical pharmacology, 180, 114147.
  • Caffarelli, C., Giannetti, A., Giannì, G., & Ricci, G. (2023). Anti-inflammatory and biologic drugs for atopic dermatitis: a therapeutic approach in children and adolescents. Frontiers in Medicine, 10.
  • Delafuente, J. C. (2003). Understanding and preventing drug interactions in elderly patients. Critical reviews in oncology/hematology, 48(2), 133-143.
  • Hunter, L. J., Wood, D. M., & Dargan, P. I. (2011). The patterns of toxicity and management of acute nonsteroidal anti-inflammatory drug (NSAID) overdose. Open access emergency medicine: OAEM, 3, 39.
  • Kay, G. G. (2000). The effects of antihistamines on cognition and performance. Journal of Allergy and Clinical Immunology, 105(6), S622-S627.
  • Lin, C. F., Wang, C. Y., & Bai, C. H. (2011). Polypharmacy, aging and potential drug-drug interactions in outpatients in Taiwan: a retrospective computerized screening study. Drugs & aging, 28, 219-225.
  • Seynaeve, S., Verbrugghe, W., Claes, B., Vandenplas, D., Reyntiens, D., & Jorens, P. G. (2011). Adverse drug events in intensive care units: a cross-sectional study of prevalence and risk factors. American Journal of Critical Care, 20(6), e131-e140.
  • Turkish Pharmaceutical Market Observation Report. Accessed December 24, 2023. Retrieved from: https://titck.gov.tr/storage/Archive/2019/.pdf
  • Van Leeuwen, R. W. F., Swart, E. L., Boven, E., Boom, F. A., Schuitenmaker, M. G., & Hugtenburg, J. G. (2011). Potential drug interactions in cancer therapy: a prevalence study using an advanced screening method. Annals of oncology, 22(10), 2334-2341.
  • Wang, H., Shi, H., Wang, N., Wang, Y., Zhang, L., Zhao, Y., & Xie, J. (2022). Prevalence of potential drug− drug interactions in the cardiothoracic intensive care unit patients in a Chinese tertiary care teaching hospital. BMC Pharmacology and Toxicology, 23(1), 1-6.
  • Yunes, L. P., Coelho, T. D. A., & de Almeida, S. M. (2011). e Serviços de Saúde, 2(3):23-6.

Evaluation of Drug-Drug Interactions in Patients Admitting to the Ear Nose and Throat Clinic

Year 2024, , 20 - 27, 30.08.2024
https://doi.org/10.55895/sshs.1427187

Abstract

Introduction: Drug interactions are effects that change the effect of the drug and therefore on the patient, mostly due to the use of drugs together at the same or recent times. Drug interactions can cause serious consequences such as the development of adverse events, ineffectiveness of the treatment, or mortality.
Materials and Methods: The prescriptions of 106 patients who applied to the ear, nose, and throat outpatient clinic between January and December 2021 were examined retrospectively.
Results: 106 prescriptions were included in the study. Twelve major, 19 moderate, and 9 minor interactions were detected in 106 prescriptions.
Conclusion: Although there are relatively few interactions compared to studies conducted with other patient groups, interactions can affect the clinical status of the patient. More attention should be paid to drug interactions in these patients, especially physicians and pharmacists.

References

  • Alvim, M. M., Silva, L. A. D., Leite, I. C. G., & Silvério, M. S. (2015). Adverse events caused by potential drug-drug interactions in an intensive care unit of a teaching hospital. Revista Brasileira de terapia intensiva, 27, 353-359.
  • Andrade, P. H. S., Santos, A. D. S., Souza, C. A. S., Lobo, I. M. F., & da Silva, W. B. (2017). Risk factors for adverse drug reactions in pediatric inpatients: a systematic review. Therapeutic advances in drug safety, 8(6), 199-210.
  • Antimicrobial Resistance Polict Insight. Accessed December 24, 2023. Retrieved from: https://www.oecd.org/health/health-systems/AMR-Policy-Insights November2016.pdf
  • Bhat, G. M. N., Holla, R., & Kamath P. S. D. (2015). A study of prescription pattern in the drug therapy of ear, nose, and throat infections at a tertiary care hospital in Mangalore. International Journal of Basic & Clinical Pharmacology, 4(4), 686–90.
  • Bindu, S., Mazumder, S., & Bandyopadhyay, U. (2020). Non-steroidal anti-inflammatory drugs (NSAIDs) and organ damage: A current perspective. Biochemical pharmacology, 180, 114147.
  • Caffarelli, C., Giannetti, A., Giannì, G., & Ricci, G. (2023). Anti-inflammatory and biologic drugs for atopic dermatitis: a therapeutic approach in children and adolescents. Frontiers in Medicine, 10.
  • Delafuente, J. C. (2003). Understanding and preventing drug interactions in elderly patients. Critical reviews in oncology/hematology, 48(2), 133-143.
  • Hunter, L. J., Wood, D. M., & Dargan, P. I. (2011). The patterns of toxicity and management of acute nonsteroidal anti-inflammatory drug (NSAID) overdose. Open access emergency medicine: OAEM, 3, 39.
  • Kay, G. G. (2000). The effects of antihistamines on cognition and performance. Journal of Allergy and Clinical Immunology, 105(6), S622-S627.
  • Lin, C. F., Wang, C. Y., & Bai, C. H. (2011). Polypharmacy, aging and potential drug-drug interactions in outpatients in Taiwan: a retrospective computerized screening study. Drugs & aging, 28, 219-225.
  • Seynaeve, S., Verbrugghe, W., Claes, B., Vandenplas, D., Reyntiens, D., & Jorens, P. G. (2011). Adverse drug events in intensive care units: a cross-sectional study of prevalence and risk factors. American Journal of Critical Care, 20(6), e131-e140.
  • Turkish Pharmaceutical Market Observation Report. Accessed December 24, 2023. Retrieved from: https://titck.gov.tr/storage/Archive/2019/.pdf
  • Van Leeuwen, R. W. F., Swart, E. L., Boven, E., Boom, F. A., Schuitenmaker, M. G., & Hugtenburg, J. G. (2011). Potential drug interactions in cancer therapy: a prevalence study using an advanced screening method. Annals of oncology, 22(10), 2334-2341.
  • Wang, H., Shi, H., Wang, N., Wang, Y., Zhang, L., Zhao, Y., & Xie, J. (2022). Prevalence of potential drug− drug interactions in the cardiothoracic intensive care unit patients in a Chinese tertiary care teaching hospital. BMC Pharmacology and Toxicology, 23(1), 1-6.
  • Yunes, L. P., Coelho, T. D. A., & de Almeida, S. M. (2011). e Serviços de Saúde, 2(3):23-6.
There are 15 citations in total.

Details

Primary Language English
Subjects Clinical Sciences (Other)
Journal Section Research Articles
Authors

Serkan Ceyhan 0000-0001-6497-0629

Sinem Gürcü 0000-0001-8534-7369

Publication Date August 30, 2024
Submission Date January 29, 2024
Acceptance Date July 8, 2024
Published in Issue Year 2024

Cite

APA Ceyhan, S., & Gürcü, S. (2024). Evaluation of Drug-Drug Interactions in Patients Admitting to the Ear Nose and Throat Clinic. Sabuncuoglu Serefeddin Health Sciences, 6(1), 20-27. https://doi.org/10.55895/sshs.1427187


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