Research Article

Simultaneous search of multiple groups of antibiotics and their different components in the honey

Volume: 1 Number: 1 August 30, 2019
EN

Simultaneous search of multiple groups of antibiotics and their different components in the honey

Abstract

The honey is a bee (Apis mellifera) product formed by the chemical change of the nectars that the bees collect from the flowers. Honey is more or less affected by the antibiotics used in bee diseases. This contagion has vital importance in terms of public health. For this reason, simultaneous and rapid detection of different antibiotic groups in the remnants of used veterinary medications is important. Simultaneous identification of different groups of antibiotics depends on the detection method of each group, the performances of the devices, and the success of the validation. This study was carried out to realize the identification, validation and method development of the multiplex-group antibiotic residues, in the direction of EU Directive 2002/657 EEC. A different method has been developed for a total of 35 antibiotics from many groups, and the detection limits, deviations, LOD, LOQ and validations are presented. It has been identified in this study that the simultaneous detection and validation of multiplex-groups of antibiotics, which have not yet been routinely practised, is possible. With this study, a unique method and a validation technique, which may be used by national competent authorities, has been developed.

Keywords

Supporting Institution

Karabük Üniversitesi

Project Number

KBU-BAP-15/1-KP-037

Thanks

Acknowledgement: This study was supported by Karabük University Scientific Research Projects Unit with the number of KBU-BAP-15/1-KP-037. I would like to thank Karabük University for their support and following this tough and long-lasting process together with me.

References

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  2. 2. Adams, S.J., Henrich, K., Hetmanski, M., Fussel, R.J., Wilkins, S., Thompson, H.M., Sharman, M. (2007). Study of the depletion of tylosin residues in honey extracted from treated honeybee (Apis mellifera) colonies and the effect of the shook swarm procedure. Apidologie 38 (2007): 315-322.
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  4. 4. Barganska, Z., Slebioda, M., Namiesnik, J. (2011). Determination of antibiotic residues inhoney. Trends in Analytical Chemistry, 30 (7):1035-1041.
  5. 5. Benetti, C., Piro,R., Binota,G., Angeletti, R., Biancotto, G. (2006). Simultaneous determination of Lincomycin and five macrolide antibiotic residues in honey by liquid chromatography coupled to electrospray ionisation mass spectrometry. Food Additives and Contaminants. 23(11): 1099-1108.
  6. 6. Bernal, J., Nozal, M.J., Jimenez, J.J., Martin, M.T., Sanz, E. (2009). A new and simple method to determine trace levels of sulfonamides in honey by high performance liquid chromatography with fluorescence detection. Journal of Chromatography A, 1216 (2009): 7275-7280.
  7. 7. Bogdanov, St. (2006): Contaminants of Bee Products. Apidologie 37 (2006). 1-18.
  8. 8. Bondi, M.C.M., Marazuela, M.D., Herranz, S., Rodriguez, E. (2009). An overview of sample preparation procedures for LC-MS multiclass antibiotic determination in environmental and food samples. A review. Analytical andBioanalytical Chemistry. (395):921-946.

Details

Primary Language

English

Subjects

-

Journal Section

Research Article

Authors

Erol Kabil
Türkiye

Hatice Kübra Koç Topçuoğlu This is me
Türkiye

Ümit Topçuoğlu This is me
Türkiye

Publication Date

August 30, 2019

Submission Date

May 21, 2019

Acceptance Date

August 16, 2019

Published in Issue

Year 2019 Volume: 1 Number: 1

APA
Bilici, N., Altuner, Y., Kabil, E., Koç Topçuoğlu, H. K., & Topçuoğlu, Ü. (2019). Simultaneous search of multiple groups of antibiotics and their different components in the honey. Sabuncuoglu Serefeddin Health Sciences, 1(1), 15-33. https://izlik.org/JA66PW48TE
AMA
1.Bilici N, Altuner Y, Kabil E, Koç Topçuoğlu HK, Topçuoğlu Ü. Simultaneous search of multiple groups of antibiotics and their different components in the honey. SSHS. 2019;1(1):15-33. https://izlik.org/JA66PW48TE
Chicago
Bilici, Namık, Yılmaz Altuner, Erol Kabil, Hatice Kübra Koç Topçuoğlu, and Ümit Topçuoğlu. 2019. “Simultaneous Search of Multiple Groups of Antibiotics and Their Different Components in the Honey”. Sabuncuoglu Serefeddin Health Sciences 1 (1): 15-33. https://izlik.org/JA66PW48TE.
EndNote
Bilici N, Altuner Y, Kabil E, Koç Topçuoğlu HK, Topçuoğlu Ü (August 1, 2019) Simultaneous search of multiple groups of antibiotics and their different components in the honey. Sabuncuoglu Serefeddin Health Sciences 1 1 15–33.
IEEE
[1]N. Bilici, Y. Altuner, E. Kabil, H. K. Koç Topçuoğlu, and Ü. Topçuoğlu, “Simultaneous search of multiple groups of antibiotics and their different components in the honey”, SSHS, vol. 1, no. 1, pp. 15–33, Aug. 2019, [Online]. Available: https://izlik.org/JA66PW48TE
ISNAD
Bilici, Namık - Altuner, Yılmaz - Kabil, Erol - Koç Topçuoğlu, Hatice Kübra - Topçuoğlu, Ümit. “Simultaneous Search of Multiple Groups of Antibiotics and Their Different Components in the Honey”. Sabuncuoglu Serefeddin Health Sciences 1/1 (August 1, 2019): 15-33. https://izlik.org/JA66PW48TE.
JAMA
1.Bilici N, Altuner Y, Kabil E, Koç Topçuoğlu HK, Topçuoğlu Ü. Simultaneous search of multiple groups of antibiotics and their different components in the honey. SSHS. 2019;1:15–33.
MLA
Bilici, Namık, et al. “Simultaneous Search of Multiple Groups of Antibiotics and Their Different Components in the Honey”. Sabuncuoglu Serefeddin Health Sciences, vol. 1, no. 1, Aug. 2019, pp. 15-33, https://izlik.org/JA66PW48TE.
Vancouver
1.Namık Bilici, Yılmaz Altuner, Erol Kabil, Hatice Kübra Koç Topçuoğlu, Ümit Topçuoğlu. Simultaneous search of multiple groups of antibiotics and their different components in the honey. SSHS [Internet]. 2019 Aug. 1;1(1):15-33. Available from: https://izlik.org/JA66PW48TE

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