Investigating The Effects Of The Induction Agents Propofol And Thiopental On Awareness During Intubation And Operation In General Anesthesia During Cesarean Section

Abstract

Aim: In addition to contributing to post-operative psychological disorders, awareness causes fear in patients undergoing surgery. In cesarean section operations, developing awareness due to low anesthetic procedures cause high risk in these patients. Thus, reducing awareness by maintaining and achieving the depth of anesthesia has become very important.

Material and Method: Forty patients undergoing caesarean section operation were divided into two groups. In the first (propofol) group, the induction of anesthesia was done by 2.5 mg/kg propofol and 0.6 mg/kg rocuronium. In the second (thiopental) group, anesthesia was induced by 5 mg/kg thiopental and 0.6 mg/kg rocuronium. In both groups after the baby was extracted, the anesthesia was maintained with desflurane. Patients’ systolic and diastolic blood pressure, heart rate, Evans Score, and Bispectral Index (BIS) values were recorded every 5 minutes.

Results: When two groups were compared in terms of awareness no significant difference was observed. However, despite BIS values ​​being within the normal limits (<60), awareness values were high.

Conclusion: Many studies have shown that, for anesthesiologists, awareness is still a serious problem during the initial stages of application of general anesthesia. In this study, the comparison between propofol and thiopental did not show any significant differences, but although the BIS values ​​were within normal limits the awareness values were high.

Keywords

• Cesarean Delivery,Awareness,General Anesthesia,Thiopental,Propofol

References

1. Referans1 .Errando CL, Sigl JC, Robles M. et al. Awareness with recall during general anaesthesia:a prospective observational evaluation of 4001 patients. Br. J. Anaes h. 2008 Aug;101(2):178-85. doi: 10.1093/bja/aen144. Epub 2008 May 30.