Case Report
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Year 2021, Volume: 3 Issue: 3, 40 - 46, 31.12.2021

Abstract

References

  • 1. Donnino MW, Vega J, Miller J, Walsh M. Myths and misconceptions of Wernicke's encephalopathy: what every emergency physician should know. Ann Emerg Med. 2007;50(6):715-21.
  • 2. Sechi G, Serra A. Wernicke's encephalopathy: new clinical settings and recent advances in diagnosis and management. Lancet Neurol. 2007;6(5):442-55.
  • 3. Antunez E, Estruch R, Cardenal C, Nicolas JM, Fernandez-Sola J, Urbano-Marquez A. Usefulness of CT and MR imaging in the diagnosis of acute Wernicke's encephalopathy. AJR Am J Roentgenol. 1998;171(4):1131-7.
  • 4. Gordon PH. Amyotrophic Lateral Sclerosis: An update for 2013 Clinical Features, Pathophysiology, Management and Therapeutic Trials. Aging Dis. 2013;4(5):295-310.
  • 5. Jesse S, Thal DR, Ludolph AC. Thiamine deficiency in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 2015;86(10):1166-8.
  • 6. UpToDate [online]. Available at: http://www.uptodate.com/contents/wernickes-encephalopathy. Accessed 22.01.2012.
  • 7. Donnino MW, Vega J, Miller J, Walsh M. Myths and misconceptions of Wernicke's encephalopathy: what every emergency physician should know. Ann Emerg Med. 2007;50(6):715-21.
  • 8. Kobayashi M, Ikeda K, Kinoshita M, Iwasaki Y. Amyotrophic lateral sclerosis with supranuclear ophthalmoplegia and rigidity. Neurol Res. 1999;21(7):661-4.
  • 9. Day E, Bentham PW, Callaghan R, Kuruvilla T, George S. Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol. Cochrane Database Syst Rev. 2013;(7):CD004033.
  • 10. Galvin R, Bråthen G, Ivashynka A, Hillbom M, Tanasescu R, Leone MA; EFNS. EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy. Eur J Neurol. 2010;17(12):1408-18.
  • 11. Beharrysingh R. Myroides bacteremia: A case report and concise review. IDCases. 2017;8:34-36.

WERNICKE ENCEPHALOPATHY: A CASE OF AMYOTROPHIC LATERAL SCLEROSIS COMPLICATION

Year 2021, Volume: 3 Issue: 3, 40 - 46, 31.12.2021

Abstract

Hypovitaminosis secondary to undernutrition is presented with clinical diseases coursing with broad spectrum symptoms. Thiamine (vitamin B1) deficiency is frequently associated with malnutrition, and causes serious neurological disorders as Wernicke’s encephalopathy (WE), and beriberi disease. Even though clinical trials have predicted the incidence of WE as 0.04-0.13 %, post-mortem studies have demonstrated a higher incidence as 0.8-2.8 % which means that most of the cases go undiagnosed. Treatment with thiamine supplementation protects the patient from all of these diseases.
In this article, a case who was diagnosed as amyotrophic lateral sclerosis who displayed Wernicke-Korsakoff syndrome pattern was discussed. This manuscript was prepared to attract attention to this potentially fatal easily overlooked Wernicke-Korsakoff syndrome pattern developing in especially undernourished amyotrophic lateral sclerosis patients with percutaneous gastrostomy (PEG) which may be mostly reversed with treatment at an early stage.

References

  • 1. Donnino MW, Vega J, Miller J, Walsh M. Myths and misconceptions of Wernicke's encephalopathy: what every emergency physician should know. Ann Emerg Med. 2007;50(6):715-21.
  • 2. Sechi G, Serra A. Wernicke's encephalopathy: new clinical settings and recent advances in diagnosis and management. Lancet Neurol. 2007;6(5):442-55.
  • 3. Antunez E, Estruch R, Cardenal C, Nicolas JM, Fernandez-Sola J, Urbano-Marquez A. Usefulness of CT and MR imaging in the diagnosis of acute Wernicke's encephalopathy. AJR Am J Roentgenol. 1998;171(4):1131-7.
  • 4. Gordon PH. Amyotrophic Lateral Sclerosis: An update for 2013 Clinical Features, Pathophysiology, Management and Therapeutic Trials. Aging Dis. 2013;4(5):295-310.
  • 5. Jesse S, Thal DR, Ludolph AC. Thiamine deficiency in amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 2015;86(10):1166-8.
  • 6. UpToDate [online]. Available at: http://www.uptodate.com/contents/wernickes-encephalopathy. Accessed 22.01.2012.
  • 7. Donnino MW, Vega J, Miller J, Walsh M. Myths and misconceptions of Wernicke's encephalopathy: what every emergency physician should know. Ann Emerg Med. 2007;50(6):715-21.
  • 8. Kobayashi M, Ikeda K, Kinoshita M, Iwasaki Y. Amyotrophic lateral sclerosis with supranuclear ophthalmoplegia and rigidity. Neurol Res. 1999;21(7):661-4.
  • 9. Day E, Bentham PW, Callaghan R, Kuruvilla T, George S. Thiamine for prevention and treatment of Wernicke-Korsakoff Syndrome in people who abuse alcohol. Cochrane Database Syst Rev. 2013;(7):CD004033.
  • 10. Galvin R, Bråthen G, Ivashynka A, Hillbom M, Tanasescu R, Leone MA; EFNS. EFNS guidelines for diagnosis, therapy and prevention of Wernicke encephalopathy. Eur J Neurol. 2010;17(12):1408-18.
  • 11. Beharrysingh R. Myroides bacteremia: A case report and concise review. IDCases. 2017;8:34-36.
There are 11 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Research Articles
Authors

Ayşe Akyüz

Publication Date December 31, 2021
Submission Date April 16, 2021
Published in Issue Year 2021 Volume: 3 Issue: 3

Cite

APA Akyüz, A. (2021). WERNICKE ENCEPHALOPATHY: A CASE OF AMYOTROPHIC LATERAL SCLEROSIS COMPLICATION. Sabuncuoglu Serefeddin Health Sciences, 3(3), 40-46.


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