Aebli, N., Goss, B. G., Thorpe, P., Williams, R., & Krebs, J. (2006). In vivo temperature profile of
intervertebral discs and vertebral endplates during vertebroplasty: an experimental study in
sheep. Spine, 31(15), 1674–1679.
Baecker, N., Tomic, A., Mika, C., Gotzmann, A., Platen, P., Gerzer, R., & Heer, M. (2003). Bone
resorption is induced on the second day of bed rest: results of a controlled crossover trial.
Journal of applied physiology (Bethesda, Md.: 1985), 95(3), 977–982.
Ensrud, K. E., & Schousboe, J. T. (2011). Clinical practice. Vertebral fractures. The New England
journal of medicine, 364(17), 1634–1642.
Farrokhi, M. R., Alibai, E., & Maghami, Z. (2011). Randomized controlled trial of percutaneous
vertebroplasty versus optimal medical management for the relief of pain and disability in
acute osteoporotic vertebral compression fractures. Journal of neurosurgery. Spine, 14(5),
561–569.
Gangi, A., Sabharwal, T., Irani, F. G., Buy, X., Morales, J. P., Adam, A., & Standards of Practice
Committee of the Society of Interventional Radiology (2006). Quality assurance guidelines for
percutaneous vertebroplasty. Cardiovascular and interventional radiology, 29(2), 173–178.
Gehlbach, S. H., Burge, R. T., Puleo, E., & Klar, J. (2003). Hospital care of osteoporosis-related
vertebral fractures. Osteoporosis international : a journal established as result of cooperation
between the European Foundation for Osteoporosis and the National Osteoporosis
Foundation of the USA, 14(1), 53–60.
Kortebein, P., Symons, T. B., Ferrando, A., Paddon-Jones, D., Ronsen, O., Protas, E., Conger, S.,
Lombeida, J., Wolfe, R., & Evans, W. J. (2008). Functional impact of 10 days of bed rest in
healthy older adults. The journals of gerontology. Series A, Biological sciences and medical
sciences, 63(10), 1076–1081.
Longo, U. G., Loppini, M., Denaro, L., Maffulli, N., & Denaro, V. (2012). Osteoporotic vertebral
fractures: current concepts of conservative care. British medical bulletin, 102, 171–189.
Lu, Q., Liu, C., Wang, D., Liu, H., Yang, H., & Yang, L. (2019). Biomechanical evaluation of calcium
phosphate-based nanocomposite versus polymethylmethacrylate cement for percutaneous
kyphoplasty. The spine journal : official journal of the North American Spine Society, 19(11),
1871–1884.
Luo, Y., Yang, D. M., Yang, H. M., Wu, D., & Xie, F. Y. (2023). Innovative minimally invasive implants
for osteoporosis vertebral compression fractures. Frontiers in medicine, 10, 1161174.
Jin, C., Xu, G., Weng, D., Xie, M., & Qian, Y. (2018). Impact of Magnetic Resonance Imaging on
Treatment-Related Decision Making for Osteoporotic Vertebral Compression Fracture: A
Prospective Randomized Trial. Medical science monitor : international medical journal of
experimental and clinical research, 24, 50–57.
Johnell, O., & Kanis, J. (2005). Epidemiology of osteoporotic fractures. Osteoporosis international
: a journal established as result of cooperation between the European Foundation for
Osteoporosis and the National Osteoporosis Foundation of the USA, 16 Suppl 2, S3–S7.
Marie, P. J., & Kassem, M. (2011). Extrinsic mechanisms involved in age-related defective bone
formation. The Journal of clinical endocrinology and metabolism, 96(3), 600–609.
https://doi.org/10.1210/jc.2010-2113
Mathis, J. M., Ortiz, A. O., & Zoarski, G. H. (2004). Vertebroplasty versus kyphoplasty: a comparison
and contrast. AJNR. American journal of neuroradiology, 25(5), 840–845.
Patel, N., Jacobs, D., John, J., Fayed, M., Nerusu, L., Tandron, M., Dailey, W., Ayala, R., Sibai, N.,
Forrest, P., Schwalb, J., & Aiyer, R. (2022). Balloon Kyphoplasty vs Vertebroplasty: A Systematic
Review of Height Restoration in Osteoporotic Vertebral Compression Fractures. Journal of
pain research, 15, 1233–1245.
Sun, H., Lu, P. P., Liu, Y. J., Yang, X., Zhou, P. H., Shen, X. F., Sun, S. W., & Yang, H. (2016). Can
Unilateral Kyphoplasty Replace Bilateral Kyphoplasty in Treatment of Osteoporotic Vertebral
Compression Fractures? A Systematic Review and Meta-analysis. Pain physician, 19(8), 551–
563.
Takahashi, S., Hoshino, M., Terai, H., Toyoda, H., Suzuki, A., Tamai, K., Watanabe, K., Tsujio, T.,
Yasuda, H., Kono, H., Sasaoka, R., Dohzono, S., Hayashi, K., Ohyama, S., Hori, Y., & Nakamura, H.
(2018). Differences in short-term clinical and radiological outcomes depending on timing of
balloon kyphoplasty for painful osteoporotic vertebral fracture. Journal of orthopaedic science
: official journal of the Japanese Orthopaedic Association, 23(1), 51–56.
Tsoumakidou, G., Too, C. W., Koch, G., Caudrelier, J., Cazzato, R. L., Garnon, J., & Gangi, A. (2017).
CIRSE Guidelines on Percutaneous Vertebral Augmentation. Cardiovascular and
interventional radiology, 40(3), 331–342.
Venmans, A., Klazen, C. A., Lohle, P. N., Mali, W. P., & van Rooij, W. J. (2012). Natural history of pain
in patients with conservatively treated osteoporotic vertebral compression fractures: results
from VERTOS II. AJNR. American journal of neuroradiology, 33(3), 519–521.
Wright, N. C., Looker, A. C., Saag, K. G., Curtis, J. R., Delzell, E. S., Randall, S., & Dawson-Hughes, B.
(2014). The recent prevalence of osteoporosis and low bone mass in the United States based
on bone mineral density at the femoral neck or lumbar spine. Journal of bone and mineral
research : the official journal of the American Society for Bone and Mineral Research, 29(11),
2520–2526.
Zhan, Y., Jiang, J., Liao, H., Tan, H., & Yang, K. (2017). Risk Factors for Cement Leakage After
Vertebroplasty or Kyphoplasty: A Meta-Analysis of Published Evidence. World neurosurgery,
101, 633–642.
Zhang, H., Xu, C., Zhang, T., Gao, Z., & Zhang, T. (2017). Does Percutaneous Vertebroplasty or
Balloon Kyphoplasty for Osteoporotic Vertebral Compression Fractures Increase the
Incidence of New Vertebral Fractures? A Meta-Analysis. Pain physician, 20(1), E13–E28.
Trends in Vertebral Augmentation Practice for Osteoporotic Vertebral Fracture
Year 2023,
Volume: 5 Issue: 3, 31 - 41, 31.12.2023
Osteoporosis is characterized by low bone mass, primarily affecting older individuals and a common complication is vertebral fractures. The collapse-induced height loss in vertebrae can result in spinal instability and progressive kyphotic deformity. Surgical intervention for osteoporotic vertebrae poses challenges due to poor bone quality and frequent medical comorbidities. In recent years, it has become the predominant method for vertebral augmentation in acute fractures, aiming to relieve pain, strengthen the vertebral structure, and prevent deformities by restoring height. These procedures involve percutaneous placement of cannulas into each collapsed vertebral body through a unipedicular or bipedicular approach.
Novel products are emerging to strengthen vertebrae in treating osteoporotic compression fractures. Balloon kyphoplasty and vertebroplasty are widely accepted and recognized as effective vertebral augmentation methods. Treatment guidelines are evolving with the introduction of innovative systems like Vertebral Body Stenting, Titanium Mesh, and Sky Bone Expander, claiming to achieve exceptional vertebral height restoration. Controversies persist regarding the optimal timing for vertebral augmentation post-fracture.
Polymethylmethacrylate cement is extensively used to stabilize fractured vertebral bodies. Additionally, new calcium phosphate-based nanocomposite cements are gaining prominence. These advancements underscore the ongoing development in the treatment of osteoporotic vertebral compression fractures. Each innovative implant introduces unique features and indications. Precise confirmation of the source of the painful fracture is crucial for effective and safe treatment, ensuring proper timing and indication.
Aebli, N., Goss, B. G., Thorpe, P., Williams, R., & Krebs, J. (2006). In vivo temperature profile of
intervertebral discs and vertebral endplates during vertebroplasty: an experimental study in
sheep. Spine, 31(15), 1674–1679.
Baecker, N., Tomic, A., Mika, C., Gotzmann, A., Platen, P., Gerzer, R., & Heer, M. (2003). Bone
resorption is induced on the second day of bed rest: results of a controlled crossover trial.
Journal of applied physiology (Bethesda, Md.: 1985), 95(3), 977–982.
Ensrud, K. E., & Schousboe, J. T. (2011). Clinical practice. Vertebral fractures. The New England
journal of medicine, 364(17), 1634–1642.
Farrokhi, M. R., Alibai, E., & Maghami, Z. (2011). Randomized controlled trial of percutaneous
vertebroplasty versus optimal medical management for the relief of pain and disability in
acute osteoporotic vertebral compression fractures. Journal of neurosurgery. Spine, 14(5),
561–569.
Gangi, A., Sabharwal, T., Irani, F. G., Buy, X., Morales, J. P., Adam, A., & Standards of Practice
Committee of the Society of Interventional Radiology (2006). Quality assurance guidelines for
percutaneous vertebroplasty. Cardiovascular and interventional radiology, 29(2), 173–178.
Gehlbach, S. H., Burge, R. T., Puleo, E., & Klar, J. (2003). Hospital care of osteoporosis-related
vertebral fractures. Osteoporosis international : a journal established as result of cooperation
between the European Foundation for Osteoporosis and the National Osteoporosis
Foundation of the USA, 14(1), 53–60.
Kortebein, P., Symons, T. B., Ferrando, A., Paddon-Jones, D., Ronsen, O., Protas, E., Conger, S.,
Lombeida, J., Wolfe, R., & Evans, W. J. (2008). Functional impact of 10 days of bed rest in
healthy older adults. The journals of gerontology. Series A, Biological sciences and medical
sciences, 63(10), 1076–1081.
Longo, U. G., Loppini, M., Denaro, L., Maffulli, N., & Denaro, V. (2012). Osteoporotic vertebral
fractures: current concepts of conservative care. British medical bulletin, 102, 171–189.
Lu, Q., Liu, C., Wang, D., Liu, H., Yang, H., & Yang, L. (2019). Biomechanical evaluation of calcium
phosphate-based nanocomposite versus polymethylmethacrylate cement for percutaneous
kyphoplasty. The spine journal : official journal of the North American Spine Society, 19(11),
1871–1884.
Luo, Y., Yang, D. M., Yang, H. M., Wu, D., & Xie, F. Y. (2023). Innovative minimally invasive implants
for osteoporosis vertebral compression fractures. Frontiers in medicine, 10, 1161174.
Jin, C., Xu, G., Weng, D., Xie, M., & Qian, Y. (2018). Impact of Magnetic Resonance Imaging on
Treatment-Related Decision Making for Osteoporotic Vertebral Compression Fracture: A
Prospective Randomized Trial. Medical science monitor : international medical journal of
experimental and clinical research, 24, 50–57.
Johnell, O., & Kanis, J. (2005). Epidemiology of osteoporotic fractures. Osteoporosis international
: a journal established as result of cooperation between the European Foundation for
Osteoporosis and the National Osteoporosis Foundation of the USA, 16 Suppl 2, S3–S7.
Marie, P. J., & Kassem, M. (2011). Extrinsic mechanisms involved in age-related defective bone
formation. The Journal of clinical endocrinology and metabolism, 96(3), 600–609.
https://doi.org/10.1210/jc.2010-2113
Mathis, J. M., Ortiz, A. O., & Zoarski, G. H. (2004). Vertebroplasty versus kyphoplasty: a comparison
and contrast. AJNR. American journal of neuroradiology, 25(5), 840–845.
Patel, N., Jacobs, D., John, J., Fayed, M., Nerusu, L., Tandron, M., Dailey, W., Ayala, R., Sibai, N.,
Forrest, P., Schwalb, J., & Aiyer, R. (2022). Balloon Kyphoplasty vs Vertebroplasty: A Systematic
Review of Height Restoration in Osteoporotic Vertebral Compression Fractures. Journal of
pain research, 15, 1233–1245.
Sun, H., Lu, P. P., Liu, Y. J., Yang, X., Zhou, P. H., Shen, X. F., Sun, S. W., & Yang, H. (2016). Can
Unilateral Kyphoplasty Replace Bilateral Kyphoplasty in Treatment of Osteoporotic Vertebral
Compression Fractures? A Systematic Review and Meta-analysis. Pain physician, 19(8), 551–
563.
Takahashi, S., Hoshino, M., Terai, H., Toyoda, H., Suzuki, A., Tamai, K., Watanabe, K., Tsujio, T.,
Yasuda, H., Kono, H., Sasaoka, R., Dohzono, S., Hayashi, K., Ohyama, S., Hori, Y., & Nakamura, H.
(2018). Differences in short-term clinical and radiological outcomes depending on timing of
balloon kyphoplasty for painful osteoporotic vertebral fracture. Journal of orthopaedic science
: official journal of the Japanese Orthopaedic Association, 23(1), 51–56.
Tsoumakidou, G., Too, C. W., Koch, G., Caudrelier, J., Cazzato, R. L., Garnon, J., & Gangi, A. (2017).
CIRSE Guidelines on Percutaneous Vertebral Augmentation. Cardiovascular and
interventional radiology, 40(3), 331–342.
Venmans, A., Klazen, C. A., Lohle, P. N., Mali, W. P., & van Rooij, W. J. (2012). Natural history of pain
in patients with conservatively treated osteoporotic vertebral compression fractures: results
from VERTOS II. AJNR. American journal of neuroradiology, 33(3), 519–521.
Wright, N. C., Looker, A. C., Saag, K. G., Curtis, J. R., Delzell, E. S., Randall, S., & Dawson-Hughes, B.
(2014). The recent prevalence of osteoporosis and low bone mass in the United States based
on bone mineral density at the femoral neck or lumbar spine. Journal of bone and mineral
research : the official journal of the American Society for Bone and Mineral Research, 29(11),
2520–2526.
Zhan, Y., Jiang, J., Liao, H., Tan, H., & Yang, K. (2017). Risk Factors for Cement Leakage After
Vertebroplasty or Kyphoplasty: A Meta-Analysis of Published Evidence. World neurosurgery,
101, 633–642.
Zhang, H., Xu, C., Zhang, T., Gao, Z., & Zhang, T. (2017). Does Percutaneous Vertebroplasty or
Balloon Kyphoplasty for Osteoporotic Vertebral Compression Fractures Increase the
Incidence of New Vertebral Fractures? A Meta-Analysis. Pain physician, 20(1), E13–E28.
There are 22 citations in total.
Details
Primary Language
English
Subjects
Clinical Sciences (Other), Health Services and Systems (Other)
Gökyar, A. (2023). Trends in Vertebral Augmentation Practice for Osteoporotic Vertebral Fracture. Sabuncuoglu Serefeddin Health Sciences, 5(3), 31-41. https://doi.org/10.55895/sshs.1398464