ANABOLIC ANDROGENIC STEROID USE DISORDER: A PUBLIC HEALTH ISSUE

Year 2025, Volume: 7 Issue: 1, 39 - 42, 30.04.2025

Servet Birgin İritaş , Bedirhan Sezer Öner

https://doi.org/10.55895/sshs.1688203

Abstract

Androgenic-anabolic steroids (AAS) are synthetic substances derived from the male hormone testosterone. According to the current scientific literature, these substances are widely used, particularly by athletes and bodybuilders, to enhance muscle mass. Beyond their use in sports, AAS are increasingly misused by a broader population seeking muscle growth without an increase in fat mass, making AAS abuse a significant public health concern. Due to the physiological, psychological, and social effects associated with AAS use and its widespread prevalence, healthcare professionals should identify patients who may be at risk and stay informed about scientific studies on the adverse health effects of these substances.
The physiological, psychological, and social consequences of AAS use pose serious risks to users' overall health and have far-reaching effects on society. Sudden cardiac death, which has been linked to the use of performance-enhancing drugs, is the most common medical cause of death among athletes.
This study highlights the public health significance of AAS use disorder, examines the reasons behind its widespread use, and explores its effects on health and available treatment options. Additionally, it underscores the importance of requesting AAS analyses, which are not routinely performed in forensic autopsy procedures, particularly in cases of suspicious deaths among athletes.

Keywords

Anabolic Androgenic Steroid , Adverse Effects , Forensic Toxicology , Sudden Cardiac Death , Public Health

References

• Anawalt, B. D. (2019). Diagnosis and management of anabolic androgenic steroid use. The Journal of Clinical Endocrinology & Metabolism, 104(7), 2490–2500. https://doi.org/10.1210/jc.2019-00084
• Baggish, A. L., Weiner, R. B., Kanayama, G., Hudson, J. I., Lu, M. T., Hoffmann, U., & Pope, H. G. (2017). Cardiovascular toxicity of illicit anabolic-androgenic steroid use. Circulation, 135(21), 1991–2002. https://doi.org/10.1161/CIRCULATIONAHA.116.026945
• Bahrke, M. S., & Yesalis, C. E. (2004). Abuse of anabolic androgenic steroids and related substances in athletes and nonathletes. The Physician and Sportsmedicine, 32(3), 3–12. https://doi.org/10.3810/psm.2004.03.198
• Brower, K. J. (2002). Anabolic steroid abuse and dependence. Current Psychiatry Reports, 4(5), 377–387. https://doi.org/10.1007/s11920-996-0006-2
• Christoffersen, T., Andersen, J. T., Dalhoff, K. P., & Horwitz, H. (2019). Anabolic-androgenic steroids and the risk of imprisonment. Drug and Alcohol Dependence, 203, 92–97. https://doi.org/10.1016/j.drugalcdep.2019.06.010
• Christou, M. A., Christou, P. A., Markozannes, G., Tsatsoulis, A., Mastorakos, G., & Tigas, S. (2017). Effects of anabolic androgenic steroids on the reproductive system of athletes and recreational users: A systematic review and meta-analysis. Sports Medicine, 47(9), 1869–1883. https://doi.org/10.1007/s40279-017-0709-z
• Demirtaş, M. İ., & Yalçın, H. (2017). Anabolik steroidlerin kullanım sıklığı ve sağlık üzerindeki etkileri: Üniversite öğrencileri üzerine bir çalışma [The frequency of anabolic steroid use and its effects on health: A study on university students]. Sağlık Bilimleri Dergisi, 5(2), 67–74.
• Gibbons, S. E., Dunne, E. M., & McMahon, E. (2020). Public health perspectives on anabolic steroid use. Journal of Public Health, 42(1), 18–27. https://doi.org/10.1093/pubmed/fdz123
• Gruber, A. J., & Pope, H. G. (2019). The effects of anabolic steroids on mood and behavior. Psychological Medicine, 49(12), 1995–2005. https://doi.org/10.1017/S0033291719001110
• Hernández-Guerra, A. I., Tapia, J., Menéndez-Quintanal, L. M., & Lucena, J. S. (2019). Sudden cardiac death in anabolic androgenic steroid abuse: A case report and literature review. Forensic Science Research, 4(3), 267–273. https://doi.org/10.1080/20961790.2019.1633761
• Kanayama, G., Brower, K. J., Wood, R. I., Hudson, J. I., & Pope, H. G. (2009). Anabolic-androgenic steroid dependence: An emerging disorder. Addiction, 104(12), 1966–1978. https://doi.org/10.1111/j.1360-0443.2009.02734.x
• National Institute on Drug Abuse (NIDA). (2024, July 11). Anabolic steroids and other appearance and performance enhancing drugs (APEDs). Retrieved March 13, 2025, from https://nida.nih.gov/research-topics/anabolic-steroids
• Torrisi, M., Pennisi, G., Russo, I., Amico, F., Esposito, M., Liberto, A., Cocimano, G., Salerno, M., Li Rosi, G., & Di Nunno, N. (2020). Sudden cardiac death in anabolic-androgenic steroid users: A literature review. Medicina, 56(11), 587. https://doi.org/10.3390/medicina56110587
• Vanberg, P., & Atar, D. (2010). Androgenic anabolic steroid abuse and the cardiovascular system. Handbook of Experimental Pharmacology, 195, 411–457. https://doi.org/10.1007/978-3-642-02824-1_16