Abstract
Daha önce sağlıklı olduğu öğrenilen 2.5 yaşındaki kız olgu acil servisimize ani bilinç kaybı ve konvülziyon geçirme nedeniyle getirildi. Olgunun çok sayıda kayısı çekirdeği yemesi sonrası mevcut klinik tablonun geliştiği öğrenildi. Olgu acil servise getirildiğinde belirgin hipotermik olup koma bulguları vardı. Çok sayıda kayısı çekirdeği yenmesi nedeniyle akut siyanür zehirlenmesi geliştiği düşünüldü. Ülkemizde bulunmadığı için uygun antidot tedavisi uygulanamadı. Ağır metabolik asidozun düzeltilmesi için sodyum bikarbonat infüzyonu uygulandı. Uygulanan destekleyici tedaviye kısa sürede yanıt veren olgunun, klinik tablosunun 8 saat içinde düzeldiği görüldü. Ülkemizden kayısı çekirdeği yenmesi sonrası siyanür zehirlenmesi gözlendiği bildirilen ikinci olgu olması nedeniyle sunumu yapıldı.
Keywords
References
- Suchard JR, Wallace KL, Gerkin RD. Acute cyanide toxicity caused by apricot kernel ingestion. Ann Emerg Med 1998; 32: 742-744. Geller RJ, Barthold C, Saiers JA, Hall AH. Pediatric cyanide po- isoning: causes, manifestations, management, and unmet needs. Pediatrics 2006; 118: 2146-2158.
- Holzbecher MD, Moss MA, Ellenberger HA. The cyanide content of laetrile preparations, apricot, peach and apple seeds. J Toxicol Clin Toxicol 1984; 22: 341-347.
- Toxicological Profile for Cyanide (Update). US Department of Health and Human Services 1997: 28.
- Chin RG, Calderon Y. Acute cyanide poisoning: a case report. J Emerg Med 2000; 18: 441-445.
- Mégarbane B, Delahaye A, Goldgran-Tolédano D, Baud FJ. An- tidotal treatment of cyanide poisoning. J Chin Med Assoc. 2003; 66: 193-203.
- Borron SW, Baud FJ. Acute cyanide poisoning: clinical spectrum, diagnosis, and treatment. Arh Hig Rada Toksikol. 1996; 47: 307- 322.
- Hall AH, Dart R, Bogdan G. Sodium thiosulfate or hydroxoco- balamin for the empiric treatment of cyanide poisoning? Ann Emerg Med. 2007; 49: 806-813.
- Brivet F, Delfraissy JF, Duche M, Bertrand P, Dormont J. Acute cyanide poisoning: recovery with non-specific supportive therapy. Intensive Care Med 1983; 9: 33-35.
- Beasley DM, Glass WI. Cyanide poisoning: pathophysiology and treatment recommendations. Occup Med (Lond) 1998; 48: 427- 431.
- Vogel SN, Sultan TR, Ten Eyck RP. Cyanide poisoning. Clin Toxi- col 1981; 18: 367-383.
- Sayre JW, Kaymakcalan S. Cyanide poisoning from apricot seeds among children in Central Turkey. N Engl J Med 1964; 270: 1113- 1115.
- Lasch EE, El Shawa R. Multiple cases of cyanide poisoning by apricot kernels in children from Gaza. Pediatrics 1981; 68: 5-7.
Abstract
Two years and six months old, previously healthy girl was admitted to our emergency department due to sudden loss of consciousness and convulsions after ingestion of lots of apricot kernels. She was comatose and hypothermic on presentation to our emergency department. We thought that cyanide intoxication after kernel ingestion was responsible for the clinical picture. Since the antidote for cyanide poisoning was unavailable in our country, antidote could not been given. For the correction of severe metabolic acidosis, sodium bicarbonate infusion was applied. By the help of supportive treatment, the patient was recovered within 8 hours. Since this was the second report of cyanide toxicity from apricot kernel ingestion from Turkey, we presented the case
Keywords
References
- Suchard JR, Wallace KL, Gerkin RD. Acute cyanide toxicity caused by apricot kernel ingestion. Ann Emerg Med 1998; 32: 742-744. Geller RJ, Barthold C, Saiers JA, Hall AH. Pediatric cyanide po- isoning: causes, manifestations, management, and unmet needs. Pediatrics 2006; 118: 2146-2158.
- Holzbecher MD, Moss MA, Ellenberger HA. The cyanide content of laetrile preparations, apricot, peach and apple seeds. J Toxicol Clin Toxicol 1984; 22: 341-347.
- Toxicological Profile for Cyanide (Update). US Department of Health and Human Services 1997: 28.
- Chin RG, Calderon Y. Acute cyanide poisoning: a case report. J Emerg Med 2000; 18: 441-445.
- Mégarbane B, Delahaye A, Goldgran-Tolédano D, Baud FJ. An- tidotal treatment of cyanide poisoning. J Chin Med Assoc. 2003; 66: 193-203.
- Borron SW, Baud FJ. Acute cyanide poisoning: clinical spectrum, diagnosis, and treatment. Arh Hig Rada Toksikol. 1996; 47: 307- 322.
- Hall AH, Dart R, Bogdan G. Sodium thiosulfate or hydroxoco- balamin for the empiric treatment of cyanide poisoning? Ann Emerg Med. 2007; 49: 806-813.
- Brivet F, Delfraissy JF, Duche M, Bertrand P, Dormont J. Acute cyanide poisoning: recovery with non-specific supportive therapy. Intensive Care Med 1983; 9: 33-35.
- Beasley DM, Glass WI. Cyanide poisoning: pathophysiology and treatment recommendations. Occup Med (Lond) 1998; 48: 427- 431.
- Vogel SN, Sultan TR, Ten Eyck RP. Cyanide poisoning. Clin Toxi- col 1981; 18: 367-383.
- Sayre JW, Kaymakcalan S. Cyanide poisoning from apricot seeds among children in Central Turkey. N Engl J Med 1964; 270: 1113- 1115.
- Lasch EE, El Shawa R. Multiple cases of cyanide poisoning by apricot kernels in children from Gaza. Pediatrics 1981; 68: 5-7.
Details
| Other ID | JA72ES64PU |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | June 1, 2009 |
| Submission Date | June 1, 2009 |
| Published in Issue | Year 2009 Volume: 3 Issue: 3 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.