Geri Çekildi: Sendromik Obez Olgularımızın Klinik Olarak Değerlendirilmesi

Year 2021, Volume: 15 Issue: 5, 379 - 385, 23.09.2021

Pınar Kocaay Derya Tepe

https://doi.org/10.12956/tchd.929957

Abstract

Amaç: Obezite; Türkiye’de ve dünyada, sıklığı giderek artan önemli bir halk sağlığı sorunudur. Sendromik obezite, obezitenin nadir ancak önemli bir nedenidir. Çalışmada amaç; obez olguların poliklinik değerlendirmesinde hangi hikaye ve fizik muayene bulguları ile sendromik obeziteden şüphenilmeli sorusunu akla getirmektir. Böylece bu olgulara erken tanı konularak hayatı tehdit edebilecek ek anomalilerin erken fark edilmesi ve tedavisi sağlanacaktır.

Gereç ve Yöntemler: Bu çalışmada Ankara Şehir Hastanesi, Çocuk Endokrinoloji polikliniğine Ocak 2019-Ocak 2021 tarihleri arasında başvurmuş ve bu yıllarda takip edilmekte olan 18 yaş altı 17 sendromik obez olgu dahil edilmiştir. Olguların fizik muayene ve antropometrik değerlendirmeleri, laboratuvar bulguları, görme ve işitme muayeneleri, renal ve hepatobiliyer görüntülemeleri, ekokardiyografik değerlendirmeleri, psikiyatrik değerlendirmeleri, ek hastalıkları, kullandıkları ilaçlar ve mevcut genetik sonuçları dosyaları taranarak toplanmıştır.

Bulgular: Çalışmaya toplam 17 olgu dahil edildi. Bu olguların dokuzu kız, sekizi erkekti. Olguların en erken tanı yaşı 2 yaş; en geç tanı yaşı 12 yaş 6 aydı. Dört olgu Prader Willi sendromu, üç olgu Bardet Biedel sendromu, altı olgu Alström sendromu, dört olgu psödohipoparatiroidi Tip1 A tanısı aldı. Başvuru şikayeti 13 olguda kilo fazlalığı, aşırı yeme isteğiydi. Ancak psödohipoparatiroidi nedeniyle başvuran üç olgunun başvuru şikayeti hipokalsemiye bağlı semptomlar iken, bir olgununki boy kısalığıydı.

Sonuç: Olgularımızda en erken tanı yaşının 2 yaş olması çocuk poliklinik muayenelerinde fizik muayene ve anamnez alımının daha dikkatli yapılması gerektiğini göstermiştir. Ayrıca olguların son poliklinik muayeneleri obezitenin önlenmesi ve takibinde beklenilen başarının sağlanamadığını göstermiştir. Ailelerin bu konuda daha fazla eğitim almaları ve tedavide daha aktif rol almaları hastaları artan obezite derecesinden ve ek komplikasyonlardan koruyacaktır.

Bu makale 24-09-2021 tarihinde geri çekildi. https://dergipark.org.tr/tr/pub/tchd/issue/65826/1018461 

Keywords

Çocuk, genetik, obezite

Retraction: Clinical Evaluation of Our Syndromic Obese Children

Abstract

Objective: Obesity is an important public health problem growing increasingly in Turkey and in the world. Syndromic obesity is a rare but an important cause of obesity. Aim of the study is bringing to mind the question of which history and physical examination findings should be suspected in outpatient evaluation of syndromic obese cases. Thus, early diagnosis and treatment of additional life-threatening anomalies will be provided in these cases.

Material and Methods: In this study, 17 syndromic obese patients under the age of 18 who applied to Ankara City Hospital Pediatric Endocrinology outpatient clinic between January 2019 and January 2021 were included. Physical examinations and anthropometric evaluations of the cases, laboratory findings, visual and hearing examinations, renal and hepatobiliary imaging, echocardiographic evaluations, psychiatric evaluations, additional diseases, their medications and available
genetic results were collected by scanning the patient files.

Results: A total of 17 cases were included in the study. Nine of these cases were girls and eight were boys. The earliest diagnosis
age of the cases was 2 years and the latest diagnosis age was 12 years and 6 months. Four cases were diagnosed with Prader Willi
syndrome, three cases with Bardet Biedel syndrome, six cases with Alström syndrome and four cases with pseudohypoparathyroidism
Type 1 A. The application complaint was excess weight and desire to eat in 13 patients. However, three patients who diagnosed with
pseudohypoparathyroidism had hypocalcemia and the other one had short stature.

Conclusion: The fact that the earliest diagnosis age was 2 years in our cases showed that polyclinic physical examinations and taking
anamnesis should be done more carefully. In addition, the last outpatient clinic examinations of the cases showed that the expected success
could not be achieved in the prevention and follow-up of obesity. If families get more education on this subject and take important role in
treatment, patients will be protected from increased obesity and additional complications.

This article was retracted on September 24, 2021. https://dergipark.org.tr/en/pub/tchd/issue/65826/1018461 

Keywords

Child, Genetics, Obesity

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