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Endometriozisde Steroid Reseptör ile Klinik Gidişin Karşılaştırılması: İmmun Dokukimyasal Bir Çalışma

Year 1997, Volume: 3 Issue: 1-2, - , 01.05.1997

Yrd.doç.dr. Dilaver Demirel Doç.dr. Richard Brown Prof.dr. Russell Malinak Prof.dr. İbrahim Öztek Prof.dr. İbrahim Ramzy

Abstract

Keywords

-

References

  • Israel ee: Endometriosis. ln Reproductive Endocrinology. Infenility and Contraception. Edited by DR Michell. ‘v' Davajan. Philadelphia. FA Davis. 19?9: 47's. Shaw evv. Endcmetricsis: The net-d: ten years. Br J Clin Prect Symp Suppl 1991 : T2: 99—99.
  • Barbieri FfL. Hormone treatment of endometriosis: The estrogen threshold hypothesis. Am J Ubstet Gynecol : 199: red-s. Ftoclr. JA. lvloutos DM. Endometrlosis: the present and the future + an overview at treatment options. Br J Obstet Gynaecol 1992: 99: Suppl ?. 1—rt.
  • Lassey BA. Metzger DA. Haney AF. McCarty KS. lmmunohistochemical analysis of estrogen and progesterone receptors in endometrlosis: comparison with normal endometrium during the menstrual cycle and the effect of medical therapy. Fertil Steril 1999: 51: 499—19. "12 slightly higher than the levels in ovarian lesions.
  • ?. Lyndrup J. Thorpe S. Glenthoi A. Cihet E. et al. Altered progesteroneieslrogen receptor ratios in endometriosis. Acta Obstet Gynecol Scand 1991'; ss: 929—9.
  • Bergqvist A. H'annevik G. Thorali J. Estrogen and progesterone cytosol receptor concentration in andometriotic tissue and intrauterine endometriurri. Acta Dostet Gynecol Scand Suppl 1991; 191: 53-3.
  • Bergovist A. Jeppson 9. Ljungberg ü. Histochemical demonstration of estrogen and progesterone binding in endometrio‘tic tissue and in uterine endometrlum: a comparative study. J Histochem Cytochem 1935: 33: 51.
  • Jenna O. Kauppila A. Koltito E. Lahtto T. et al. Estrogen and progestin receptors in endcmetriosis lesions: comparison with endometrlel tissue. Am .J Ühstet Gynecol ; 1111:5535. o. Demirel. a. Brown. e. Marines. i. özeli. i. eamzy irem ise; sc te:—itici easy-Heisman: eer.” re cetesi-+ $"? ı “ei 3333* $ t6: ? Wifi— 9-“3199 *.“tt' *? it". i-‘f‘i‘f‘a‘: 9-35“ i' ’5‘. 't'“. >- sii-were.trees-'s.:“.itritieeweenadese-seite- sees: .ii—tsre'ireswe

Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study

Year 1997, Volume: 3 Issue: 1-2, - , 01.05.1997

Yrd.doç.dr. Dilaver Demirel Doç.dr. Richard Brown Prof.dr. Russell Malinak Prof.dr. İbrahim Öztek Prof.dr. İbrahim Ramzy

Abstract

Endometriozisin klinik olarak gidişi ve steroid reseptör durumu arasındaki ilişkiyi belirlemek amaoıyla estrogen reseptör [EFT] ve progesteron reseptör {PR} için immün dokukimyasal boylar: endometriozisl'ı 15 hastanın endometriotik lezyonlarının (n: 1?) ve endometriumlarının to: 3] formatinda fikse edilip paratinde bloklanan kesitlerine uygulandı. Onbeş hastanın yedisine preoperatif hormonal sağaltım yapıldı. Endometriumlarrn tamamında ve 1? endometriotik lezyonun lö'sında, bezlerde ve stromada EFi ve F'Ft için spesifik nükleer boyanma gözlendi. Boyanma şiddeti (T+-3+,l ve yaygınlığı t1+-4+jı semikarıtitatil olarak belirlendi. Preoperatif hormonal sağaltımlı hastalarla, diğerleri arasında anlamlı bir boyanma ayrımı gözlenmedi. Üveryumdaki ln: ?) ve ovaryum dışındaki tn: to] endometrial implantlar benzer boyanma paterni gösterdi. Sonuç olarak; belirgin klinik bulgusu olan endometriozisli hastaların endometriotik lezyonlarında immün dokukimyasal yöntemle estrogen ve progesteron reseptörlerinin üniform olarak bulunduğu saptanmıştır. Preoperatif hormonal sağaltım ile reseptörlerde anlamlı bir azalma izlenmemiştir

Keywords

Endometriosis steroid reseptör— leri estrogen reseptörü. progesteron reseptörü

References

  • Israel ee: Endometriosis. ln Reproductive Endocrinology. Infenility and Contraception. Edited by DR Michell. ‘v' Davajan. Philadelphia. FA Davis. 19?9: 47's. Shaw evv. Endcmetricsis: The net-d: ten years. Br J Clin Prect Symp Suppl 1991 : T2: 99—99.
  • Barbieri FfL. Hormone treatment of endometriosis: The estrogen threshold hypothesis. Am J Ubstet Gynecol : 199: red-s. Ftoclr. JA. lvloutos DM. Endometrlosis: the present and the future + an overview at treatment options. Br J Obstet Gynaecol 1992: 99: Suppl ?. 1—rt.
  • Lassey BA. Metzger DA. Haney AF. McCarty KS. lmmunohistochemical analysis of estrogen and progesterone receptors in endometrlosis: comparison with normal endometrium during the menstrual cycle and the effect of medical therapy. Fertil Steril 1999: 51: 499—19. "12 slightly higher than the levels in ovarian lesions.
  • ?. Lyndrup J. Thorpe S. Glenthoi A. Cihet E. et al. Altered progesteroneieslrogen receptor ratios in endometriosis. Acta Obstet Gynecol Scand 1991'; ss: 929—9.
  • Bergqvist A. H'annevik G. Thorali J. Estrogen and progesterone cytosol receptor concentration in andometriotic tissue and intrauterine endometriurri. Acta Dostet Gynecol Scand Suppl 1991; 191: 53-3.
  • Bergovist A. Jeppson 9. Ljungberg ü. Histochemical demonstration of estrogen and progesterone binding in endometrio‘tic tissue and in uterine endometrlum: a comparative study. J Histochem Cytochem 1935: 33: 51.
  • Jenna O. Kauppila A. Koltito E. Lahtto T. et al. Estrogen and progestin receptors in endcmetriosis lesions: comparison with endometrlel tissue. Am .J Ühstet Gynecol ; 1111:5535. o. Demirel. a. Brown. e. Marines. i. özeli. i. eamzy irem ise; sc te:—itici easy-Heisman: eer.” re cetesi-+ $"? ı “ei 3333* $ t6: ? Wifi— 9-“3199 *.“tt' *? it". i-‘f‘i‘f‘a‘: 9-35“ i' ’5‘. 't'“. >- sii-were.trees-'s.:“.itritieeweenadese-seite- sees: .ii—tsre'ireswe
There are 7 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Yrd.doç.dr. Dilaver Demirel This is me

Doç.dr. Richard Brown This is me

Prof.dr. Russell Malinak This is me

Prof.dr. İbrahim Öztek This is me

Prof.dr. İbrahim Ramzy This is me

Publication Date May 1, 1997
Published in Issue Year 1997 Volume: 3 Issue: 1-2

Cite

APA Demirel, Y. D., Brown, D. R., Malinak, P. R., Öztek, P. İ., et al. (1997). Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study. Türkiye Ekopatoloji Dergisi, 3(1-2).
AMA Demirel YD, Brown DR, Malinak PR, Öztek Pİ, Ramzy Pİ. Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study. Türkiye Ekopatoloji Dergisi. May 1997;3(1-2).
Chicago Demirel, Yrd.doç.dr. Dilaver, Doç.dr. Richard Brown, Prof.dr. Russell Malinak, Prof.dr. İbrahim Öztek, and Prof.dr. İbrahim Ramzy. “Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study”. Türkiye Ekopatoloji Dergisi 3, no. 1-2 (May 1997).
EndNote Demirel YD, Brown DR, Malinak PR, Öztek Pİ, Ramzy Pİ (May 1, 1997) Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study. Türkiye Ekopatoloji Dergisi 3 1-2
IEEE Y. D. Demirel, D. R. Brown, P. R. Malinak, P. İ. Öztek, and P. İ. Ramzy, “Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study”, Türkiye Ekopatoloji Dergisi, vol. 3, no. 1-2, 1997.
ISNAD Demirel, Yrd.doç.dr. Dilaver et al. “Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study”. Türkiye Ekopatoloji Dergisi 3/1-2 (May 1997).
JAMA Demirel YD, Brown DR, Malinak PR, Öztek Pİ, Ramzy Pİ. Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study. Türkiye Ekopatoloji Dergisi. 1997;3.
MLA Demirel, Yrd.doç.dr. Dilaver et al. “Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study”. Türkiye Ekopatoloji Dergisi, vol. 3, no. 1-2, 1997.
Vancouver Demirel YD, Brown DR, Malinak PR, Öztek Pİ, Ramzy Pİ. Correlation of Steroid Receptor Status and Clinical Course of Endometriosis: An Immunohistochemical Study. Türkiye Ekopatoloji Dergisi. 1997;3(1-2).