BibTex RIS Cite

Azaserin Enjekte Edilmiş Sıçan Asinar Hücrelerinde Az Görülen Karsinoma In Situ'nun Morfolojik ve Biyolojik Özellikleri

Year 1998, Volume: 4 Issue: 1-2, - , 01.05.1998

Haydar Öztaş M.akif Çiftçioğlu

Abstract

Keywords

-

References

  • Cubiıla AL. and Fitzgerald PJ. Morphoiogical patterns of primary nonendocrine human pancreas carcinoma. Cancer Flas 19?5'. 35. 2234-2248.
  • Cubilla AL and Fitzgerald PJ. Morphological lesions associated with human primary invasive nonendocrine pancreas cancer. Cancer Flee 19m; 36. 2690-2693.
  • Longnecker DS. Wiebitin P. Schaeffer BK. Roebuck BD. Experimental Carcinogenesis in the pancreas. Int Flew Exper Pathol 1934; 26. 1??+22B.
  • Longnecker DS. Experimental models of exocrine pancreatic tumours. in: The exocrine pancreas: Biology. Pathobiology. and Diseases: Go. v.L.w. Ed.. New Yeri-t Fiaven Press. 1986: 443455.
  • Sugio K. Gazdar AF. Albums-Saavedra J. Kokkinakis DM. High yield of K-ras mutations in intracluctai papillary mucinous tumors and invasive adenocarcinomas induced by Nanitroso [2-hydroxypropyl} [2~oxcpropyl] emine in pancreas of temele Syrian hamsters. Carcinogenesis 1995: 1112]: 303-309.
  • Tür-idye Eicopatoioii Dergisi 1993: 4 ( 1—2): ta'—15 L...—qi:
  • E. Öztaş H. Characterisation cl a transiticnal type of pancreatic atypicalacinar cell fool [AACFj induced by azaserine In rats. Tr J Med Scion 1995: 26. iSE—TB.
  • Hac MS. Upton MP. Subbarac V. Scarpelli DG. Two populations of cells with differing proliferalive capacities in atypical acinar cell foci induced by 4 hvdrcıyamincqui— nclirte 1 oxide in the rat pancreas. Lab Invest 1932; 45. 521534.
  • Roebuck BD. Baumgartner KJ. Thrcn CD. Characteri- zation of two populations of pancreatic atypicai acinar cell feci induced by azaserine in the rat. Lab. Invest. 1934: 50 {21:141-146.
  • Longnecker DS. Millar PM. Tumours oi the Pancreas. in: Pathology of Tumours in Laboratory Animals. Turusov v. Mehr U. Eds. 1il'e 1 Second editlemeler]; 241-251

The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats

Year 1998, Volume: 4 Issue: 1-2, - , 01.05.1998

Haydar Öztaş M.akif Çiftçioğlu

Abstract

Karsinoma In Situ'nun sıçan pankreas kanserinin gelişiminde etkili olduğu uzun zamandır bilinmektedir. Bu çalışmada normal koşullarda sıçan pankreasında nadir olarak gözlenen, ancak azaserin uygulaması sonucu sıçan pankreasında meydana getirilebilen bir karsinoma In Sltu'nun histopatolojik özellikleri incelenmiştir. Onaltı günlük toplam 10 sıçana vücut ağırlığı esas alınarak iötlmglkgjı intra peritonal olarak azaserin enjekte edilmiş ve yavruların 21 günlük oluncaya kadar annelerini emmelerine izin verilmiştir, Yirmibir günün so— nunda azaserin enjekte edlien 1ü sıçan ve. [aynı yaşta) azaserln enjekte edilmemiş 10 tane sıçan (kontrol grubu) normal standart bir diyetle 1B ay süresince beslenmişIerdir. Bu süre sonunda sıçanlar öldürülerek pankreasları çıkarılmışı tesbit edilerek histopatolojik özellikleri incelenmiştir. Insan ve hayvanlarda kanal {dental} kaynaklı karsinoma in situnun yüksek olmasına karşın bu çalışmada gözlenen asinar hücre kökenli karsinoma in situ'da desmoplazik ve eozinofilik yapılar izlenmiş oluo. proliferatif bir üzelllk gözlenmiştir. Bu sonuçlar, mekaniz— ması tam olarak bilinmemekle birlikte. karsinoma in situ‘nun pankreas kanserinin meydana gelmesinde etkili olabileceği yolundaki hipotezi destekler niteliktedir

Keywords

Karsinoma in situ. azaserin. sıçan

References

  • Cubiıla AL. and Fitzgerald PJ. Morphoiogical patterns of primary nonendocrine human pancreas carcinoma. Cancer Flas 19?5'. 35. 2234-2248.
  • Cubilla AL and Fitzgerald PJ. Morphological lesions associated with human primary invasive nonendocrine pancreas cancer. Cancer Flee 19m; 36. 2690-2693.
  • Longnecker DS. Wiebitin P. Schaeffer BK. Roebuck BD. Experimental Carcinogenesis in the pancreas. Int Flew Exper Pathol 1934; 26. 1??+22B.
  • Longnecker DS. Experimental models of exocrine pancreatic tumours. in: The exocrine pancreas: Biology. Pathobiology. and Diseases: Go. v.L.w. Ed.. New Yeri-t Fiaven Press. 1986: 443455.
  • Sugio K. Gazdar AF. Albums-Saavedra J. Kokkinakis DM. High yield of K-ras mutations in intracluctai papillary mucinous tumors and invasive adenocarcinomas induced by Nanitroso [2-hydroxypropyl} [2~oxcpropyl] emine in pancreas of temele Syrian hamsters. Carcinogenesis 1995: 1112]: 303-309.
  • Tür-idye Eicopatoioii Dergisi 1993: 4 ( 1—2): ta'—15 L...—qi:
  • E. Öztaş H. Characterisation cl a transiticnal type of pancreatic atypicalacinar cell fool [AACFj induced by azaserine In rats. Tr J Med Scion 1995: 26. iSE—TB.
  • Hac MS. Upton MP. Subbarac V. Scarpelli DG. Two populations of cells with differing proliferalive capacities in atypical acinar cell foci induced by 4 hvdrcıyamincqui— nclirte 1 oxide in the rat pancreas. Lab Invest 1932; 45. 521534.
  • Roebuck BD. Baumgartner KJ. Thrcn CD. Characteri- zation of two populations of pancreatic atypicai acinar cell feci induced by azaserine in the rat. Lab. Invest. 1934: 50 {21:141-146.
  • Longnecker DS. Millar PM. Tumours oi the Pancreas. in: Pathology of Tumours in Laboratory Animals. Turusov v. Mehr U. Eds. 1il'e 1 Second editlemeler]; 241-251
There are 10 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Haydar Öztaş This is me

M.akif Çiftçioğlu This is me

Publication Date May 1, 1998
Published in Issue Year 1998 Volume: 4 Issue: 1-2

Cite

APA Öztaş, H., & Çiftçioğlu, M. (1998). The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats. Türkiye Ekopatoloji Dergisi, 4(1-2).
AMA Öztaş H, Çiftçioğlu M. The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats. Türkiye Ekopatoloji Dergisi. May 1998;4(1-2).
Chicago Öztaş, Haydar, and M.akif Çiftçioğlu. “The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats”. Türkiye Ekopatoloji Dergisi 4, no. 1-2 (May 1998).
EndNote Öztaş H, Çiftçioğlu M (May 1, 1998) The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats. Türkiye Ekopatoloji Dergisi 4 1-2
IEEE H. Öztaş and M. Çiftçioğlu, “The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats”, Türkiye Ekopatoloji Dergisi, vol. 4, no. 1-2, 1998.
ISNAD Öztaş, Haydar - Çiftçioğlu, M.akif. “The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats”. Türkiye Ekopatoloji Dergisi 4/1-2 (May 1998).
JAMA Öztaş H, Çiftçioğlu M. The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats. Türkiye Ekopatoloji Dergisi. 1998;4.
MLA Öztaş, Haydar and M.akif Çiftçioğlu. “The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats”. Türkiye Ekopatoloji Dergisi, vol. 4, no. 1-2, 1998.
Vancouver Öztaş H, Çiftçioğlu M. The Morphologic and Biologic Patterns of a Rare Carcinoma In Situ (CIS) of Acinar Cells in Azaserine Treated Rats. Türkiye Ekopatoloji Dergisi. 1998;4(1-2).