Investigation of the Risk Factors of Diabetic Neuropathy in terms of Pain, Sleep and Quality of Life

Abstract

Purpose: Neuropathy is one of the most common complications of diabetes mellitus and affects the quality of life. The aim of this study was to investigate the risk factors in terms of sleep, pain and quality of life and associated symptoms for diabetic neuropathy.

Methods: Two hundred and seventy-six individuals with diabetes mellitus were included the study, and divided into two groups randomly according to having neuropathy or not. Physical and clinical characteristics were recorded. Pain intensity, social and working life quality, and complaint of non-restorative sleep were assessed by Visual Analogue Scale. The Mann Whitney U test and independent samples t-test were used to analyze time-dependent changes. Non-time-dependent changes were analyzed by the chi-square test. Logistic regression was done for analyzing the multiple risk factors in the groups.

Results: There were not significant differences between the groups for the following characteristics: age, gender, smoking habit, alcohol consumption, type of diabetes, body mass index (p> 0.05). Duration of disease (p=0.007), pain intensity (p< 0.001), complaint of non-restorative sleep (p=0.046) were higher, social and working life quality (p= 0.038) were lower in neuropathic patients.

Discussion: Duration of disease as a potential risk factor, pain intensity, sleeping complaints and quality of life as the most complained symptoms for diabetic neuropathy should be taken into account for prevention, early detection, and appropriate treatment.

Keywords

• Diabetic Neuropathy,Pain,Sleep,Quality of Life

AĞRI, UYKU VE YAŞAM KALİTESİ AÇISINDAN DİYABETİK NÖROPATİ RİSK FAKTÖRLERİNİN İNCELENMESİ

Abstract

Amaç: Nöropati, diyabetes mellitüsün en önemli komplikasyonlarından biridir ve günlük yaşamı etkilemektedir. Bu çalışmanın amacı uyku, ağrı ve yaşam kalitesi ve ilişkili semptomlar aracılığıyla diabetik nöropatinin risk farktörlerini belirlemekti.

Yöntemler: Çalışmaya 276 diyabetes mellitüsü olan birey dahil edildi ve nöropatiye sahip olma veya olmamaya göre rastgele ikiye ayrıldı. Fiziksel ve klinik özellikler kaydedildi. Ağrı yoğunluğu, sosyal ve iş yaşamı kalitesi ve dinlendirici olmayan uyku şikâyeti Görsel Analog Skala ile değerlendirildi. Zaman bağlı değişiklikler analiz etmek için “Mann-Whitney U testi” ve “Bağımsız Örneklem T testi” kullanıldı. Ki-Kare testi ile zamana bağlı olmayan değişiklikler analiz edildi. Lojistik regresyon ise gruplar içerisinde birden fazla risk faktörünü analiz etmek için yapıldı.

Sonuçlar: Gruplar arasında takip eden parametreler için istatistiksel olarak anlamlılık bulunmadı; yaş, cinsiyet, sigara içme alışkanlığı, alkol tüketimi, diyabet tipi, beden-kütle indeksi (p>0,05). Nöropatik hastalarda hastalık süresi (p=0,007), ağrı yoğunluğu (p< 0.001), dinlendirici olmayan uykudan şikâyet (p=0.046) daha yüksek, sosyal ve iş yaşamı kalitesi (p=0.038) ise daha düşüktü.

Tartışma: Diyabetik nöropati için hastalık süresi potansiyel bir risk faktörüdür; ağrı yoğunluğu, uyku şikâyetleri ve yaşam kalitesi ise koruma, erken teşhis ve uygun tedavi için dikkate alınması gereken çok şikâyet edilen semptomlardır.

Keywords

• Diyabetik Nöropati,Ağrı,Uyku,Yaşam Kalitesi

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