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Akut Koroner Sendromlu Hastalarda Anksiyete ve Depresyonu Belirleyen Faktörler

Year 2015, Volume: 26 Issue: 1, 40 - 46, 20.04.2015

Abstract

Amaç: Akut koroner sendromu olan hastalarda, anksiyete ve depresyon sık karşılaşılan ve kardiyak rehabilitasyon sürecini etkileyen sağlık sorunlarıdır. Bu çalışmada; akut koroner sendromlu hastalarda anksiyete ve depresyon düzeyini belirleyen faktörlerin araştırılması amaçlandı.

Yöntemler: Çalışmaya akut koroner sendrom tanısı ile koroner bakım ünitesinde izlenen 50 hasta (42 erkek, 8 kadın) katıldı. Olguların fiziksel, fizyolojik ve demografik özellikleri kaydedildi. Akut Koroner Olaylarda Küresel Kayıt (GRACE) risk puanı hesaplandı. Fonksiyonel düzey, New York Kalp Birliği (NHYA) sınıflaması ile belirlendi. Anksiyete düzeyi, Durumluk ve Sürekli Kaygı Envanteri (STAI); depresyon düzeyi Beck Depresyon Envanteri (BDI) kullanılarak belirlendi. Bilişsel fonksiyonlar, Mini-Mental Durum Değerlendirmesi (MMSE) kullanılarak değerlendirildi.

Sonuçlar: Çoklu doğrusal regresyon analizine göre, BDI ve NYHA sınıfı, STAI-Sürekli Anksiyete puanındaki değişimin % 45’ini açıkladı (p=0.016). Eğitim süresi, önceden geçirilmiş perkütan girişimin varlığı ve koroner bakıma ilk yatışta kaydedilen solunum frekansı değeri,

STAI-Durumluk Anksiyete puanının % 39’unu açıkladı (p<0.0001). STAI-Sürekli Anksiyete puanı ve MMSE puanı, BDI puanındaki değişimin % 37’sini belirledi (p<0.0001).

Tartışma: Akut koroner sendromda, fonksiyonel düzey, eğitim süresi, bilişsel fonksiyon, önceki perkütan uygulamalar ve ilk yatışta kaydedilen solunum frekansı değeri, depresyon ve anksiyete düzeyini belirlemektedir. Kardiyak rehabilitasyon programları planlanırken fiziksel fonksiyonların yanı sıra psikososyal durumunda göz önünde bulundurulmalıdır.

References

  • T.C. Sağlık Bakanlığı. Hastalık yükü maliyet etkililik çalışması. Refik Saydam Hıfzıssıhha Merkezi Başkanlığı, Hıfzıssıhha Mektebi Müdürlüğü, Ankara; 2004.
  • 2. Bunker SJ, Colquhoun DM, Esler MD, Hickie IB, Hunt D, Jelinek VM, et al. ‘Stress’ and coronary heart disease: psychosocial risk factors. Med J Aust. 2003;178(6):272-6.
  • 3. Davidson KW. Emotional predictors and behavioral triggers of acute coronary syndrome. Cleve Clin J Med. 2008;75:Suppl 2-p;15-9.
  • 4. Llyod-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, et al. Heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation. 2010;121(7):46-215.
  • 5. Di Benedetto M, Lindner H, Hare DL, Kent S. The role of coping anxiety and stress in depression post-acute coronary syndrome. Psychol Health Med. 2007;12(4):460-9.
  • 6. Pedersen SS, Smith OR, De Vries J, Apples A, Denollet J. Course of anxiety symptoms over an 18-month period in exhausted patients post percutaneous coronary intervention. Psychosom Med. 2008;70(3):349-55.
  • 7. Parker GB, Owen CA, Brotchie HL, Hyett MP. The impact of differing anxiety disorders on outcome following an acute coronary syndrome: time to start worrying? Depress Anxiety. 2010;27(3):302-9.
  • 8. Carney RM, Freedland KE. Depression, mortality, and medical morbidity in patients with coronary heart disease. Biol Psychiat. 2003;54(3):241-7.
  • 9. Kubzansky LD, Davidson KW, Rozanski A. The clinical impact of negative psychological states: expanding the spectrum of risk for coronary artery disease. Psychosom Med. 2005;67:Suppl 1-p10-4.
  • de Jonge P, Spijkerman TA, van den Brink RHS, Ormel J. Depression after myocardial infarction is a risk factor for declining health related quality of life and increased disability and cardiac complaints at 12 months. Heart. 2006;92(1):32-9.
  • 11. Huffman JC, Celano CM, Januzzi JL. The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes. Neuropsychiatr Dis Treat. 2010;6:123-36.
  • 12. Eggermont LHP, de Boer K, Muller M, Jaschke AC, Kamp O, Scherder EJA. Cardiac disease and cognitive impairment: a systematic review. Heart. 2012;98(18):1334-440.
  • 13. Gure TR, Blaum CS, Giordani B, Koelling TM, Galecki A, Pressler SJ, et al. Prevalence of cognitive impairment in older adults with heart failure. J Am Geriatr Soc. 2012;60(9):1724-9.
  • 14. Volonghi I, Pendlebury ST, Welch SJV, Mehta Z, Rothwell PW. Cognitive outcomes after acute coronary syndrome: a population based comparison with transient ischaemic attack and minor stroke. Heart. 2013;99(20):1509-14.
  • Stroobant N, Van Nooten G, Vingerhoets G. Effect of cardiovascular disease on hemodynamic response to cognitive activation: a functional transcranial Doppler study. Eur J Neurol. 2004;11(11):749-54.
  • 16. McGrady A, McGinnis R, Badenhop D, Bentle M, Rajput M. Effects of depression and anxiety on adherence to cardiac rehabilitation. J Cardiopulm Rehabil Prev. 2009;29(6):358-64.
  • 17. Bauer LK, Caro MA, Beach SR, Mastromauro CA, Lenihan E, Januzzi JL, et al. Effects of depression and anxiety improvement on adherence to medication and health behaviors in recently hospitalized cardiac patients. Am J Cardiol. 2012;109(9):1266-71.
  • 18. Tisminetzky M, Bray BC, Miozzo R, Aupont O, McLaughlin TJ. Identifying symptom profiles of depression and anxiety in patients with an acute coronary syndrome using latent class and latent transition analysis. Int J Psychiatry Med. 2011;42(2):195-210.
  • Hansen BH, Hanash JA, Rasmussen A, Hansen JF, Birket-Smith M. Comparison of participants and non-participants in a randomized study of prevention of depression in patients with acute coronary syndrome. Nord J Psychiatry. 2011;65(1):22-5.
  • 20. Tang EW, Wong CK, Herbison P. Global Registry of Acute Coronary Events (GRACE) hospital discharge risk score accurately predicts long-term mortality post acute coronary syndrome. Am Heart J. 2007;153(1):29-35.
  • 21. GRACE Investigators. Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: A multinational registry of patients hospitalized with acute coronary syndromes. Am Heart J. 2001;141(2):190-9.
  • 22. Goldman L, Hashimoto B, Cook EF, Loscalzo A. Comparative reproducibility and validity of systems for assessing cardiovascular functional class: advantages of a new specific activity scale. Circulation. 1981;64(6):1227-34.
  • 23. Aydemir O, Koroglu E. Psikiyatride kullanılan klinik ölçekler. 1st ed. Ankara: Hekimler Yayın Birliği; 2000.
  • 24. Gungen C, Ertan T, Eker E, Yasar R, Engin F. Reliability and validity of the standardized Mini Mental State Examination in the diagnosis of mild dementia in Turkish population. Turk Psikiyatri Derg. 2002;13(4):273-81.
  • 25. Green SB, Salkind NJ, Akey TM. Using SPSS for Windows: Analyzing and understanding data. 2nd ed. New Jersey: Prentice Hall; 2000.
  • 26. Hayran M, Hayran M. Sağlık araştırmaları için temel istatistik. 1st ed. Ankara: Omega yayınları; 2011.
  • 27. Glassman AH, Bigger JT, Gaffney M, Shapiro PA, Swenson JR. Onset of major depression associated with acute coronary syndromes: relationship of onset, major depressive disorder history, and episode severity to sertraline benefit. Arch Gen Psychiatry. 2006;63(3):283-8.
  • Fontana AF, Kerns RD, Rosenberg RL, Colonese KL. Support, stress, and recovery from coronary heart disease: a longitudinal causal model. Health Psychol. 1989;8(2):175-93.
  • 29. Ladwig KH, Schoefinius A, Dammann G, Danner R, Gürtler R, Herrmann R. Long-acting psychotraumatic properties of a cardiac arrest experience. Am J Psychiatry. 1999;156(6):912-9.
  • 30. Frasure-Smith N, Lespérance F. Coronary artery disease, depression and social support only the beginning. Eur Heart J. 2000;21(13):1043-5.
  • 31. Lauzon C, Beck CA, Huynh T, Dion D, Racine N, Carignan S, et al. Depression and prognosis following hospital admission because of acute myocardial infarction. CMAJ. 2003;168(5):547-52.
  • 32. Trelawny-Ross C, Russell O. Social and psychological responses to myocardial infarction: multiple determinants of outcome at six months. J Psychosom Res. 1987;31(1):125-30.
  • 33. Spielberger, CD. Manual for the State-Trait Anxiety Inventory STAI (Form Y). Palo Alto, CA: Consulting Psychologists Press; 1983.
  • 34. Schaffer JA, Edmondson D, Chaplin WF, Schwartz JE, Shimbo D, Burg MM, et al. Directionality of the relationship between depressive symptom dimensions and C-reactive protein in patients with acute coronary syndrome. Psychosom Med. 2011;73(5):370-7.
  • 35. Miller GE, Freedland KE, Carney RM, Stetler CA, Banks WA. Pathways linking depression, adiposity, and inflammatory markers in healthy young adults. Brain Behav Immun. 2003; 17 (4): 276-85.
  • 36. Vardar Yagli N, Saglam M, Inal ID, Calik E, Arikan H, Savci S, et al. Relationship between physical activity, quality of life and psychosocial function in patients with acute coronary syndrome. Turk J Physiother Rehabil. 2013;24(2):151-5.
  • 37. Jakobsen AH, Foldager L, Parker G, Munk-Jørgensen P. Quantifying links between acute myocardial infarction and depression, anxiety and schizophrenia using case register databases. J Affect Disord. 2008;109(1-2):177-81.
  • 38. Chiavarino C, Rabellino D, Ardito RB, Cavallero E, Palumbo L, Bergerone S, et al. Emotional coping is better predictor of cardiac prognosis than depression and anxiety. J Psychosom Res. 2012;73(6):473-5.
  • 39. Ladwig KH, Lederbogen F, Albus C, Angermann C, Borggrefe M, Fischer D, et al. Position paper on the importance of psychosocial factors in cardiology: Update 2013. Ger Med Sci. 2014;12: Doc09.

DETERMINANTS OF ANXIETY AND DEPRESSION LEVEL IN PATIENTS WITH ACUTE CORONARY SYNDROME

Year 2015, Volume: 26 Issue: 1, 40 - 46, 20.04.2015

Abstract

Purpose: Anxiety and depression are common health problems affecting course of the cardiac rehabilitation in patients with acute coronary syndrome. The purpose of this study was to investigate the determinants of anxiety and depression in patients with acute coronary

syndrome.

Methods: Fifty patients (42 males, 8 females) hospitalized in coronary care unit with a diagnosis of acute coronary syndrome participated in the study. Physical, physiological and demographic characteristics of the patients were recorded. The Global Registry of Acute

Coronary Events (GRACE) risk score was calculated. Functional level was determined using the New York Heart Association Classification (NYHA). Anxiety was evaluated using the State-Trait Anxiety Inventory (STAI). Depression was determined using the Beck Depression Inventory (BDI). Cognitive function evaluated using the Mini Mental State Examination (MMSE).

Results: According to multiple linear regression analysis, the BDI score and NYHA class explained 45% of the variance in the STAI-Trait Anxiety score (p=0.016). Duration of education, previous percutaneous intervention, and coronary care unit admission respiratory rate explained 39% of STAI-State Anxiety score (p<0.0001). The STAI-Trait Anxiety score and MMSE score explained 37% of the variance in the BDI score (p<0.0001).

Conclusion: Functional level, duration of education, cognitive function, previous percutaneous applications, and admission respiratory rate determine depression and anxiety level in acute coronary syndrome. Psychosocial status as well as physical function should be taken into consideration to plan in to the cardiac rehabilitation programs.

References

  • T.C. Sağlık Bakanlığı. Hastalık yükü maliyet etkililik çalışması. Refik Saydam Hıfzıssıhha Merkezi Başkanlığı, Hıfzıssıhha Mektebi Müdürlüğü, Ankara; 2004.
  • 2. Bunker SJ, Colquhoun DM, Esler MD, Hickie IB, Hunt D, Jelinek VM, et al. ‘Stress’ and coronary heart disease: psychosocial risk factors. Med J Aust. 2003;178(6):272-6.
  • 3. Davidson KW. Emotional predictors and behavioral triggers of acute coronary syndrome. Cleve Clin J Med. 2008;75:Suppl 2-p;15-9.
  • 4. Llyod-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, et al. Heart disease and stroke statistics-2010 update: a report from the American Heart Association. Circulation. 2010;121(7):46-215.
  • 5. Di Benedetto M, Lindner H, Hare DL, Kent S. The role of coping anxiety and stress in depression post-acute coronary syndrome. Psychol Health Med. 2007;12(4):460-9.
  • 6. Pedersen SS, Smith OR, De Vries J, Apples A, Denollet J. Course of anxiety symptoms over an 18-month period in exhausted patients post percutaneous coronary intervention. Psychosom Med. 2008;70(3):349-55.
  • 7. Parker GB, Owen CA, Brotchie HL, Hyett MP. The impact of differing anxiety disorders on outcome following an acute coronary syndrome: time to start worrying? Depress Anxiety. 2010;27(3):302-9.
  • 8. Carney RM, Freedland KE. Depression, mortality, and medical morbidity in patients with coronary heart disease. Biol Psychiat. 2003;54(3):241-7.
  • 9. Kubzansky LD, Davidson KW, Rozanski A. The clinical impact of negative psychological states: expanding the spectrum of risk for coronary artery disease. Psychosom Med. 2005;67:Suppl 1-p10-4.
  • de Jonge P, Spijkerman TA, van den Brink RHS, Ormel J. Depression after myocardial infarction is a risk factor for declining health related quality of life and increased disability and cardiac complaints at 12 months. Heart. 2006;92(1):32-9.
  • 11. Huffman JC, Celano CM, Januzzi JL. The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes. Neuropsychiatr Dis Treat. 2010;6:123-36.
  • 12. Eggermont LHP, de Boer K, Muller M, Jaschke AC, Kamp O, Scherder EJA. Cardiac disease and cognitive impairment: a systematic review. Heart. 2012;98(18):1334-440.
  • 13. Gure TR, Blaum CS, Giordani B, Koelling TM, Galecki A, Pressler SJ, et al. Prevalence of cognitive impairment in older adults with heart failure. J Am Geriatr Soc. 2012;60(9):1724-9.
  • 14. Volonghi I, Pendlebury ST, Welch SJV, Mehta Z, Rothwell PW. Cognitive outcomes after acute coronary syndrome: a population based comparison with transient ischaemic attack and minor stroke. Heart. 2013;99(20):1509-14.
  • Stroobant N, Van Nooten G, Vingerhoets G. Effect of cardiovascular disease on hemodynamic response to cognitive activation: a functional transcranial Doppler study. Eur J Neurol. 2004;11(11):749-54.
  • 16. McGrady A, McGinnis R, Badenhop D, Bentle M, Rajput M. Effects of depression and anxiety on adherence to cardiac rehabilitation. J Cardiopulm Rehabil Prev. 2009;29(6):358-64.
  • 17. Bauer LK, Caro MA, Beach SR, Mastromauro CA, Lenihan E, Januzzi JL, et al. Effects of depression and anxiety improvement on adherence to medication and health behaviors in recently hospitalized cardiac patients. Am J Cardiol. 2012;109(9):1266-71.
  • 18. Tisminetzky M, Bray BC, Miozzo R, Aupont O, McLaughlin TJ. Identifying symptom profiles of depression and anxiety in patients with an acute coronary syndrome using latent class and latent transition analysis. Int J Psychiatry Med. 2011;42(2):195-210.
  • Hansen BH, Hanash JA, Rasmussen A, Hansen JF, Birket-Smith M. Comparison of participants and non-participants in a randomized study of prevention of depression in patients with acute coronary syndrome. Nord J Psychiatry. 2011;65(1):22-5.
  • 20. Tang EW, Wong CK, Herbison P. Global Registry of Acute Coronary Events (GRACE) hospital discharge risk score accurately predicts long-term mortality post acute coronary syndrome. Am Heart J. 2007;153(1):29-35.
  • 21. GRACE Investigators. Rationale and design of the GRACE (Global Registry of Acute Coronary Events) Project: A multinational registry of patients hospitalized with acute coronary syndromes. Am Heart J. 2001;141(2):190-9.
  • 22. Goldman L, Hashimoto B, Cook EF, Loscalzo A. Comparative reproducibility and validity of systems for assessing cardiovascular functional class: advantages of a new specific activity scale. Circulation. 1981;64(6):1227-34.
  • 23. Aydemir O, Koroglu E. Psikiyatride kullanılan klinik ölçekler. 1st ed. Ankara: Hekimler Yayın Birliği; 2000.
  • 24. Gungen C, Ertan T, Eker E, Yasar R, Engin F. Reliability and validity of the standardized Mini Mental State Examination in the diagnosis of mild dementia in Turkish population. Turk Psikiyatri Derg. 2002;13(4):273-81.
  • 25. Green SB, Salkind NJ, Akey TM. Using SPSS for Windows: Analyzing and understanding data. 2nd ed. New Jersey: Prentice Hall; 2000.
  • 26. Hayran M, Hayran M. Sağlık araştırmaları için temel istatistik. 1st ed. Ankara: Omega yayınları; 2011.
  • 27. Glassman AH, Bigger JT, Gaffney M, Shapiro PA, Swenson JR. Onset of major depression associated with acute coronary syndromes: relationship of onset, major depressive disorder history, and episode severity to sertraline benefit. Arch Gen Psychiatry. 2006;63(3):283-8.
  • Fontana AF, Kerns RD, Rosenberg RL, Colonese KL. Support, stress, and recovery from coronary heart disease: a longitudinal causal model. Health Psychol. 1989;8(2):175-93.
  • 29. Ladwig KH, Schoefinius A, Dammann G, Danner R, Gürtler R, Herrmann R. Long-acting psychotraumatic properties of a cardiac arrest experience. Am J Psychiatry. 1999;156(6):912-9.
  • 30. Frasure-Smith N, Lespérance F. Coronary artery disease, depression and social support only the beginning. Eur Heart J. 2000;21(13):1043-5.
  • 31. Lauzon C, Beck CA, Huynh T, Dion D, Racine N, Carignan S, et al. Depression and prognosis following hospital admission because of acute myocardial infarction. CMAJ. 2003;168(5):547-52.
  • 32. Trelawny-Ross C, Russell O. Social and psychological responses to myocardial infarction: multiple determinants of outcome at six months. J Psychosom Res. 1987;31(1):125-30.
  • 33. Spielberger, CD. Manual for the State-Trait Anxiety Inventory STAI (Form Y). Palo Alto, CA: Consulting Psychologists Press; 1983.
  • 34. Schaffer JA, Edmondson D, Chaplin WF, Schwartz JE, Shimbo D, Burg MM, et al. Directionality of the relationship between depressive symptom dimensions and C-reactive protein in patients with acute coronary syndrome. Psychosom Med. 2011;73(5):370-7.
  • 35. Miller GE, Freedland KE, Carney RM, Stetler CA, Banks WA. Pathways linking depression, adiposity, and inflammatory markers in healthy young adults. Brain Behav Immun. 2003; 17 (4): 276-85.
  • 36. Vardar Yagli N, Saglam M, Inal ID, Calik E, Arikan H, Savci S, et al. Relationship between physical activity, quality of life and psychosocial function in patients with acute coronary syndrome. Turk J Physiother Rehabil. 2013;24(2):151-5.
  • 37. Jakobsen AH, Foldager L, Parker G, Munk-Jørgensen P. Quantifying links between acute myocardial infarction and depression, anxiety and schizophrenia using case register databases. J Affect Disord. 2008;109(1-2):177-81.
  • 38. Chiavarino C, Rabellino D, Ardito RB, Cavallero E, Palumbo L, Bergerone S, et al. Emotional coping is better predictor of cardiac prognosis than depression and anxiety. J Psychosom Res. 2012;73(6):473-5.
  • 39. Ladwig KH, Lederbogen F, Albus C, Angermann C, Borggrefe M, Fischer D, et al. Position paper on the importance of psychosocial factors in cardiology: Update 2013. Ger Med Sci. 2014;12: Doc09.
There are 39 citations in total.

Details

Subjects Health Care Administration
Journal Section Articles
Authors

Naciye Vardar Yağlı

Deniz İnal İnce

Melda Sağlam

Ebru Çalık Kütükçü This is me

Hülya Arıkan

Publication Date April 20, 2015
Published in Issue Year 2015 Volume: 26 Issue: 1

Cite

APA Vardar Yağlı, N., İnal İnce, D., Sağlam, M., Çalık Kütükçü, E., et al. (2015). Akut Koroner Sendromlu Hastalarda Anksiyete ve Depresyonu Belirleyen Faktörler. Fizyoterapi Rehabilitasyon, 26(1), 40-46.
AMA Vardar Yağlı N, İnal İnce D, Sağlam M, Çalık Kütükçü E, Arıkan H. Akut Koroner Sendromlu Hastalarda Anksiyete ve Depresyonu Belirleyen Faktörler. Fizyoterapi Rehabilitasyon. April 2015;26(1):40-46.
Chicago Vardar Yağlı, Naciye, Deniz İnal İnce, Melda Sağlam, Ebru Çalık Kütükçü, and Hülya Arıkan. “Akut Koroner Sendromlu Hastalarda Anksiyete Ve Depresyonu Belirleyen Faktörler”. Fizyoterapi Rehabilitasyon 26, no. 1 (April 2015): 40-46.
EndNote Vardar Yağlı N, İnal İnce D, Sağlam M, Çalık Kütükçü E, Arıkan H (April 1, 2015) Akut Koroner Sendromlu Hastalarda Anksiyete ve Depresyonu Belirleyen Faktörler. Fizyoterapi Rehabilitasyon 26 1 40–46.
IEEE N. Vardar Yağlı, D. İnal İnce, M. Sağlam, E. Çalık Kütükçü, and H. Arıkan, “Akut Koroner Sendromlu Hastalarda Anksiyete ve Depresyonu Belirleyen Faktörler”, Fizyoterapi Rehabilitasyon, vol. 26, no. 1, pp. 40–46, 2015.
ISNAD Vardar Yağlı, Naciye et al. “Akut Koroner Sendromlu Hastalarda Anksiyete Ve Depresyonu Belirleyen Faktörler”. Fizyoterapi Rehabilitasyon 26/1 (April 2015), 40-46.
JAMA Vardar Yağlı N, İnal İnce D, Sağlam M, Çalık Kütükçü E, Arıkan H. Akut Koroner Sendromlu Hastalarda Anksiyete ve Depresyonu Belirleyen Faktörler. Fizyoterapi Rehabilitasyon. 2015;26:40–46.
MLA Vardar Yağlı, Naciye et al. “Akut Koroner Sendromlu Hastalarda Anksiyete Ve Depresyonu Belirleyen Faktörler”. Fizyoterapi Rehabilitasyon, vol. 26, no. 1, 2015, pp. 40-46.
Vancouver Vardar Yağlı N, İnal İnce D, Sağlam M, Çalık Kütükçü E, Arıkan H. Akut Koroner Sendromlu Hastalarda Anksiyete ve Depresyonu Belirleyen Faktörler. Fizyoterapi Rehabilitasyon. 2015;26(1):40-6.