The Correlation between Biomarkers and Chest Computed Tomography Findings and the Severity of COVID-19 Patients

Abstract

ABSTRACT Purpose: This study aims to reveal the correlation between some biomarkers and chest computed tomography findings and the severity of patients with COVID-19. Materials and Methods: COVID-19 patients admitted to the emergency department and hospitalized between 20 March 2020 and 31 May 2020 were included in the study. Blood tests taken in the emergency room and chest computed tomography findings were examined. The risk factors for the severity and mortality of the chest computed tomography findings and biomarkers in terms of intensive care needs of COVID-19 patients were assessed. Results: Data from 113 COVID-19 patients were reviewed retrospectively. Of these patients, 40 did not have pulmonary involvement. The most common chest computed tomography finding was ground-glass opacity (n=47, 41.6%). In 16 patients with COVID-19 hospitalized in the intensive care unit and 7 patients with COVID-19 with the risk of mortality, it was found that severe pulmonary involvement and leukocyte, neutrophil, D-dimer, troponin I, urea, LDH, CRP, and procalcitonin values were significantly higher, and lymphocyte, thrombocyte, and albumin levels were significantly lower. Conclusion: It was observed that the need for intensive care and the mortality risk increased when there was an increase in leukocyte, neutrophil, D-dimer, CRP, procalcitonin, urea, and troponin values, and severe computed tomography findings, and a decrease in lymphocyte, thrombocyte, and albumin values.

Keywords

• Biomarkers
• Chest computed tomography
• COVID-19
• Mortality

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