Tip 2 Diyabet hastalığı ve bozulmuş glikoz toleransı olan kadınlarda asemptomatik bakteriüri ve üriner sistem enfeksiyonları

Öz

Amaç: Çalışmamızda; tip 2 diabetes mellitusu DM olan ve bozulmuş glikoz toleransı BGT olan iki kadın hasta grubunun üriner sistem infeksiyonu ÜSİ ve asemptomatik bakteriüri ASB varlığı ve ilişkili risk faktörleri açısından karşılaştırılması amaçlandı. Risk faktörleri olarak; yaş, vücut kitle indeksi VKİ , serum HbA1c ve kreatinin seviyeleri, glomerüler filtrasyon oranı GFR , idrardaki lökosit sayısı, glikoz miktarı ve mikroalbumin düzeyi seçildi. Yöntem: Diyabetli 208 kadın hasta ve BGT’si olan 208 kadın hasta çalışmaya dahil edildi. Serum HbA1c ve kreatinin seviyeleri ve idrardaki lökosit sayısı, glikoz miktarı ve mikroalbumin düzeyi biyokimya laboratuvarında ölçüldü. GFR, Cockcroft-Gault formula kullanılarak hesaplandı. Hastalardan alınan orta akım idrarı mikrobiyoloji laboratuvarında kanlı agar ve EMB agara ekildi. Bulgular: Diyabetli hasta grubunda beş %2 hastada, BGT hasta grubunda 15 %7 hastada ASB saptandı. ÜSİ; diyabetik grupta dokuz %4 hastada , BGT hasta grubunda yedi %3 hastada belirlendi p>0.05 . Piyüri; her iki hasta grubunda ASB ile ilişkili risk faktörü idi p

Anahtar Kelimeler

• Diabetes mellitus, bozulmuş glikoz toleransı, üriner sistem infeksiyonu, asemptomatik bakteriüri

Asymptomatic bacteriuria, urinary tract infection and risk factors in women with type 2 diabetes mellitus and impaired glucose tolerance

Abstract

Objective: We aimed to compare a type 2 diabetic women groups with a women group with impaired glucose tolerance IGT for the presence of urinary tract infection UTI and/or asymptomatic bacteriuria ASB and related risk factors [age, body mass index BMI , serum HbA1c and creatinine levels, glomerular filtration rate GFR , and urine microalbumin, urine leukocyte and glucose levels] associated therewith. Methods: The study population consisted of 416 female patients and divided into two groups as the type 2 diabetes mellitus DM, n=208 and the IGT n=208 group. Serum HbA1c and creatinine levels and leukocyte counts, glucose level and microalbumin level in the urine, were measured in the biochemistry laboratory. GFR was calculated using the Cockcroft-Gault formula. Urine samples were inoculated on blood agar and EosinMethylene Blue agar medium and incubated for 24-48 hour at 37°C. Results: ASB was determined in 5 patients 2% in the DM group and in 15 patients 7% in the IGT group. UTI was detected in 9 patients 4% in the diabetic group and in 7 patients 3% in the IGT group p>0.05 . Pyuria was found as an ASB-related risk factor in both groups p

Keywords

• diabetes mellitus, impaired glucose tolerance, urinary tact infection, asymptomatic bacteriuria

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