Polikistik over sendromunda progesterone tedavisinin pulmoner fonksiyonlara etkisi

Öz

Amaç: Çalışmamızda, polikistik over sendromlu hastaların solunum fonksiyon testlerinin ve progesteron tedavisinin değerlendirilmesi amaçlanmıştır.solunum fonksiyonlarına etkisinin second FEV1 and forced vital capacity FVC values were found increased after the treatment. Conclusion: Although the pulmonary function of PCOS patients were not different from that of the healthy female population, progesterone treatment has been shown to increase FEV1 and FVC parameters. değerleri ile kontrol grubu arasında anlamlı farklılık saptanmazken, tedavi sonrası FEV1 ve FVC değerleri artmış bulundu

Anahtar Kelimeler

• Polikistik over sendromu, medroksiprogesteron asetat, solunum fonksiyon testi

Effects of progesterone treatment in polycystic ovary syndrome on pulmonary functions

Abstract

Objective: We aimed to evaluate patients with polycystic ovary syndrome in terms of respiratory function tests and to investigate the relationship between progesterone therapy and pulmonary functions.Methods: Fifty patients, who were diagnosed polycystic ovary syndrome PCOS according to Rotterdam criteria, at gynecology and obstetrics clinic of a research and training hospital included in the study group. Fifty healthy person were included in the control group. Both groups were evaluated with pulmonary function tests PFT at pulmonary medicine clinic of a university hospital. Independent from PFT survey, the patient group was treated with two cycles of medroxyprogesterone acetate between 16 and 25 days of the cycle as the standart follow up and treatment at gynecology and obstetrics clinic. Afterwards they were evaluated with PFT again. Statistical analysis of independent measurements were analyzed by Student’s t-test. Mann-Whitney U, Wilcoxon test was used to analyze the data without normal distribution. P value

Keywords

• Polycystic ovary syndrome, medroxyprogesterone acetate, pulmonary function test

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