Toksoplazmoz Tanısında Polimeraz Zincir Reaksiyonunun Yeri

Year 2000, Volume: 57 Issue: 3 - Volume: 57 Issue: 3, 195 - 202, 01.12.2000

Semra Tunçbilek

Abstract

Toxoplasma gondiitüm dünyada insanlarda sık görülen infeksiyon etkenlerinden biridir. İnsantoksoplazmozunun laboratuvar tanısı klasik olarak serolojik testlere dayanmaktadır. Fakat bu testler immünsupresehastalardaki toksoplazma ensefaliti ve pnömonisi ile intrauterin toksoplazma infeksiyonu ve oküler toksoplazmozuntanısında yetersiz kalmaktadır. Polimeraz zincir reaksiyonunun PZR insan örneklerinde kullanılarak T.gondii’yibelirlemedeki yeri birçok çalışma ile araştırılmaktadır. Sonuçlar PZR’nunun intrauterin, oküler, serebral vedissemine toksoplazmozda kullanılabilecek hızlı ve duyarlı bir test olduğunu göstermektedir

Keywords

Toksoplazmoz, polimeraz zincir reaksiyonu

The Role Of Polymerase Chaın Reaction In The Diagnosis Of Toxoplasmosis

Abstract

Toxoplasma gondiiis one of the most common infectious agents among humans throughout the world.Laboratory diagnosis of human toxoplasmosis has relied traditionally on serological tests. But these tests areinadequate in immunocompromised patients toxoplasma encephalitis and pneumonia, intrauterine toxoplasmainfections and ocular toxoplasmosis. Many studies have done to assess the value of detecting T.gondiiin humansamples using polymerase chain reaction PCR . Findings created that PCR could be a rapid and sensitivetechnique for the diagnose of intrauterine, ocular, cerebral and disseminated toxoplasmosis

Keywords

Toxoplasmosis, polymerase chain rection

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