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Tüberkülinin Pürifiye Protein Derivesi

Year 2001, Volume: 58 Issue: 1, 27 - 32, 01.03.2001

Berrin Gençer

Abstract

“Purified Protein Derivative of Tuberculin” PPD Tüberkülin ; kültürde üretilmiş olan bir veya daha fazla Mycobacterium tuberculosis suşunun ısıtılarak parçalanması ile elde edilen, suda eriyen protein yapısındaki ürünlerden sağlanan bir preparattır. Bu preparat aynı tür mikroorganizma ile duyarlı hale getirilmiş bir konağa intradermal olarak verildiğinde gecikmiş tip aşırı duyarlılık reaksiyonu meydana getirmektedir 1 . PPD tüberkülin deri testi Mantoux testi tüberküloz enfeksiyonunu saptamak amacıyla bir asırdan fazla süredir kullanılan bir yöntemdir 2 .

References

  • Çavdar T. Tüberkülin testi. In: Kocabaş A (ed). Tüberküloz kliniği ve kontrolü. Ankara 1986; 227-231.
  • Comstock GW. Field trials of tuberculosis vaccines: How could we have done them better? Controlled Clinical Trials 1994; 15: 247-76.
  • WHO Technical Report Series 1987, No:745, Annex I, p:31-59.
  • American Thoracic Society. The tuberculin skin test. Am Rev Respir Dis 1981; 124: 356-63.
  • Molina-Gamboa JD, Leon-Rosales SP, Rivera-Morales I. Evaluation of the sensitivity of RT-23 purified protein derivative for determining tuberculin reactivity in a group of health care workers. Clin Infect Dis 1994; 19: 784-6.
  • Magnusson M, Guld J, Magnus K. Diluents for stabilization of tuberculin. Bull WHO 1958; 19: 799-828.
  • WHO Technical Report Series 1968; 384: 14.
  • Nyabenda J, Bautens E, Borremans M. The production of mycobacterial antigens by homogeneous culture in a fermentor. J Biol Standard 1988; 16: 259-67.
  • Shigeto E, Tasaka H, Yamamoto M. Tuberculin sensitivity to purified protein derivatives from Mycobacterium other than tuberculosis (PPD-B, PPD-Y, PPD-F and PPD-C) and PPDs among patients with mycobacteriosis-coop- erative study of research (Abstract). Kekkaku 1993; 68: 351-61.
  • Kocabaş A. Akciğer tüberkülozu. In: Topçu AW, Söyletir G, Doğanay M (eds). İnfeksiyon Hastalıkları, Nobel Tıp Kitabevleri 1996; 396-443.
  • Gordin FM, Perez-Stable EJ, Reid M. Stability of positive tuberculin tests: are boosted reactions valid? Am Rev Respir Dis 1991; 144: 560-3.
  • Menzies R, Vissanjee B. Effect of Bacilli Calmette-Guerin vaccination on tuberculin reactivity. Am Rev Respir Dis ; 145: 621-5.
  • Nemir RL, Krasinski K. Tuberculosis in children and adolescent in the 1980s. Pediatr Infect Dis J 1988; 7: 375-9.
  • Gemicioğlu B. Tüberkülin testi. Klinik Gelişim 1998; 11: 608-10.
  • Alcaide J, Altet MN, Batalla J. Comparative study of human cutaneous sensitivity to 2 and 5 international units of the PPD RT-23 tuberculin with Tween 80. Med Clin (Barc) (Abstract) 1992; Oct 31; 99 (14): 525-8.
  • Kendig EL, Kirkpatrick BV, Carter WH. Underreading of the tuberculin skin test. Chest 1998; 113 (5): 1175-7.
  • Rose DN, Schechter CB, Adler JJ. Interpretation of the tuberculin skin test. J Gen Intern Med 1995; 10 (11): 642.
  • Pio A, Chaulet P. The increasing TB burden. In: Tuberculosis handbook, World Health Organization. 1998:
  • Bothamley GH. Serological diagnosis of tuberculosis. Eur Respir J (Suppl) 1995; 20 (9): 676-88.
  • Amicosante M, Barnini S, Corsini V. Evaluation of a novel tuberculosis complex-specific 34 kDa protein in the serological diagnosis of tuberculosis. Eur Respir J 1995; 8 (12): 2008-14.
  • Pottumarthy S, Morris JM, Harrison AC. Evaluation of the tuberculin gamma interferon assay: Potential to replace the Mantoux skin test. J Clin Microbiol 1999; 37 (10): 3229-3232.
  • Pottumarthy S,Wells VJ, Morris JM. A comparison of seven tests for serological diagnosis of tuberculosis. J Clin Microbiol 2000; 38 (6): 2227-2231.

Purified Protein Derivative Of Tuberculin

Year 2001, Volume: 58 Issue: 1, 27 - 32, 01.03.2001

Berrin Gençer

Abstract

References

  • Çavdar T. Tüberkülin testi. In: Kocabaş A (ed). Tüberküloz kliniği ve kontrolü. Ankara 1986; 227-231.
  • Comstock GW. Field trials of tuberculosis vaccines: How could we have done them better? Controlled Clinical Trials 1994; 15: 247-76.
  • WHO Technical Report Series 1987, No:745, Annex I, p:31-59.
  • American Thoracic Society. The tuberculin skin test. Am Rev Respir Dis 1981; 124: 356-63.
  • Molina-Gamboa JD, Leon-Rosales SP, Rivera-Morales I. Evaluation of the sensitivity of RT-23 purified protein derivative for determining tuberculin reactivity in a group of health care workers. Clin Infect Dis 1994; 19: 784-6.
  • Magnusson M, Guld J, Magnus K. Diluents for stabilization of tuberculin. Bull WHO 1958; 19: 799-828.
  • WHO Technical Report Series 1968; 384: 14.
  • Nyabenda J, Bautens E, Borremans M. The production of mycobacterial antigens by homogeneous culture in a fermentor. J Biol Standard 1988; 16: 259-67.
  • Shigeto E, Tasaka H, Yamamoto M. Tuberculin sensitivity to purified protein derivatives from Mycobacterium other than tuberculosis (PPD-B, PPD-Y, PPD-F and PPD-C) and PPDs among patients with mycobacteriosis-coop- erative study of research (Abstract). Kekkaku 1993; 68: 351-61.
  • Kocabaş A. Akciğer tüberkülozu. In: Topçu AW, Söyletir G, Doğanay M (eds). İnfeksiyon Hastalıkları, Nobel Tıp Kitabevleri 1996; 396-443.
  • Gordin FM, Perez-Stable EJ, Reid M. Stability of positive tuberculin tests: are boosted reactions valid? Am Rev Respir Dis 1991; 144: 560-3.
  • Menzies R, Vissanjee B. Effect of Bacilli Calmette-Guerin vaccination on tuberculin reactivity. Am Rev Respir Dis ; 145: 621-5.
  • Nemir RL, Krasinski K. Tuberculosis in children and adolescent in the 1980s. Pediatr Infect Dis J 1988; 7: 375-9.
  • Gemicioğlu B. Tüberkülin testi. Klinik Gelişim 1998; 11: 608-10.
  • Alcaide J, Altet MN, Batalla J. Comparative study of human cutaneous sensitivity to 2 and 5 international units of the PPD RT-23 tuberculin with Tween 80. Med Clin (Barc) (Abstract) 1992; Oct 31; 99 (14): 525-8.
  • Kendig EL, Kirkpatrick BV, Carter WH. Underreading of the tuberculin skin test. Chest 1998; 113 (5): 1175-7.
  • Rose DN, Schechter CB, Adler JJ. Interpretation of the tuberculin skin test. J Gen Intern Med 1995; 10 (11): 642.
  • Pio A, Chaulet P. The increasing TB burden. In: Tuberculosis handbook, World Health Organization. 1998:
  • Bothamley GH. Serological diagnosis of tuberculosis. Eur Respir J (Suppl) 1995; 20 (9): 676-88.
  • Amicosante M, Barnini S, Corsini V. Evaluation of a novel tuberculosis complex-specific 34 kDa protein in the serological diagnosis of tuberculosis. Eur Respir J 1995; 8 (12): 2008-14.
  • Pottumarthy S, Morris JM, Harrison AC. Evaluation of the tuberculin gamma interferon assay: Potential to replace the Mantoux skin test. J Clin Microbiol 1999; 37 (10): 3229-3232.
  • Pottumarthy S,Wells VJ, Morris JM. A comparison of seven tests for serological diagnosis of tuberculosis. J Clin Microbiol 2000; 38 (6): 2227-2231.
There are 22 citations in total.

Details

Primary Language Turkish
Journal Section Collection
Authors

Berrin Gençer This is me

Publication Date March 1, 2001
Published in Issue Year 2001 Volume: 58 Issue: 1

Cite

APA Gençer, B. (2001). Tüberkülinin Pürifiye Protein Derivesi. Türk Hijyen Ve Deneysel Biyoloji Dergisi, 58(1), 27-32.
AMA Gençer B. Tüberkülinin Pürifiye Protein Derivesi. Turk Hij Den Biyol Derg. March 2001;58(1):27-32.
Chicago Gençer, Berrin. “Tüberkülinin Pürifiye Protein Derivesi”. Türk Hijyen Ve Deneysel Biyoloji Dergisi 58, no. 1 (March 2001): 27-32.
EndNote Gençer B (March 1, 2001) Tüberkülinin Pürifiye Protein Derivesi. Türk Hijyen ve Deneysel Biyoloji Dergisi 58 1 27–32.
IEEE B. Gençer, “Tüberkülinin Pürifiye Protein Derivesi”, Turk Hij Den Biyol Derg, vol. 58, no. 1, pp. 27–32, 2001.
ISNAD Gençer, Berrin. “Tüberkülinin Pürifiye Protein Derivesi”. Türk Hijyen ve Deneysel Biyoloji Dergisi 58/1 (March 2001), 27-32.
JAMA Gençer B. Tüberkülinin Pürifiye Protein Derivesi. Turk Hij Den Biyol Derg. 2001;58:27–32.
MLA Gençer, Berrin. “Tüberkülinin Pürifiye Protein Derivesi”. Türk Hijyen Ve Deneysel Biyoloji Dergisi, vol. 58, no. 1, 2001, pp. 27-32.
Vancouver Gençer B. Tüberkülinin Pürifiye Protein Derivesi. Turk Hij Den Biyol Derg. 2001;58(1):27-32.