BİYOLOJİK SİLAH OLARAK BAKTERİLER: “Kategori A ajanlar”

Year 2006, Volume: 63 Issue: 1, 21 - 46, 01.04.2006

Selçuk Kılıç

Abstract

Ölümcül, kolayca elde edilebilen ve düşük maliyet ile büyük miktarlarda üretilebilen, aerosol formda stabil olan,kolayca geniş alanlara yayılabilen ve insandan insana bulaşan bakteriyel patojenler biyolojik savaş veyabiyoterörizm ajanı olarak kullanılabilirler. Biyolojik silah ajanları yayılım özellikleri ve oluşturdukları hastalıktablosunun şiddeti ve ölüme bağlı olarak CDC tarafından üç kategoriye ayrılmıştır. Şarbon, veba ve tularemi etkeniolan bakteriler aerosol yolla şiddetli akciğer enfeksiyonuna neden olarak çoğunlukla ölümcül seyreden hastalıktablosu oluşturdukları için en yüksek risk grubu olarak tanımlanan Kategori A’da yer almaktadırlar. Bu derlemedeKategori A’da yer alan bu bakteriyel ajanların mikrobiyolojik özellikleri, biyolojik silah potansiyeleri, oluşturduklarıklinik belirtiler, tanı, korunma ve tedavileri gözden geçirilmiştir

Keywords

Biyolojik silah, şarbon, veba, tularemi

BACTERIA AS AGENTS OF BIOLOGICAL WEAPONS: “Category A agents”

Abstract

Bacterial pathogens that are lethal, relatively easily obtained and inexpensive to produce in large quantities,stable in aerosol with the ability to be dispersed over wide areas, communicable from person to person can be usedas weapons of biological warfare or bioterrorism. Biological warfare agents can be separated into three categoriesby Center of Diseases Control and prevention, depending on how easily they can be spread and the severity ofillness or death they cause. Bacterial pathogens that are considered the highest risk in category A agents in regardto their microbiology, potential for weaponization, and the clinical features, diagnosis, prevention, and treatment ofthe diseases that they cause has been reviewed

Keywords

Biowarfare agent, anthrax, plaque, tularemia

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