Amaç: Yara yeri enfeksiyonları, hastane kaynaklı enfeksiyonların en yaygın olanlarından birisidir. Önemli bir morbidite ve mortalite sebebidir. Çalışmamızda, yara yeri örneklerinden izole ettiğimiz mikroorganizmaların dağılım oranları ve antibiyotik duyarlılıkları belirlenmiş, ampirik tedavi seçeneklerine yol gösterici, hekimlerin kontrollü ve akılcı antibiyotik kullanımına yardımcı olması amaçlanmıştır.Yöntem: Yara örneklerinden 2010-2015 yılları arasında üretilen toplam 693 bakteri ve mantarın dağılım oranları araştırılmıştır.Bulgular: Üreyen mikroorganizmaların %52,5 364 ’ini Gram pozitif koklar, %42,9 297 ’unu Gram negatif basiller ve %4,6 32 ’sını mantarlar oluşturmuştur. Gram pozitif bakteriler arasında en sık rastlananlar %88,1 ile stafilokoklar olurken, bunların %41,4’ünün Staphylococcus aureus olduğu görülmüştür. Gram negatif bakterilerden en sık Escherichia coli %30,6 ve Pseudomonas türleri %18,2 gözlenmiştir. Üreyen mikroorganizmaların %4,6’sını maya mantarları oluşturmuştur. Direnç durumlarına bakıldığında metisilin direnci S. aureus’ta %35,8, koagülaz negatif stafilokoklar KNS ’da %71,1 oranlarında bulunmuş; en yüksek ve en düşük direnç sırasıyla S. aureus’ta %81,4 ile penisiline, was found in S. aureus to be 81.4% to penicillin and 3.2% to fucidic acid. When the resistance status of Gram negative bacteria was studied, it was found out that the highest resistance was 100% to ampicillin/sulbactam, cefoxitine, cefixime, cefuroxime and cefuroksime axetile in Acinetobacter, 93.7% ampicillin in E. coli, 83.3% to piperacillin in Klebsiella species, and 100% to ampicillin/sulbactam in P. aeruginosa, on the other hand, the lowest resistance was 2.8% to meropenem in E. coli, 14.2% to sefoksitin in Klebsiella species, 19.1% to gentamycin in P. aeruginosa, and no resistance developed to trimethoprim/sulfamethoxazole and tetracycline in Acinetobacter species. Conclusion: In this study, the distribution antibiotic susceptibility of microorganisms most frequently causing wound infections were determined in our hospital, the data were compared and contrasted to those of the studies made in our country and abroad, and similarities and differences were disclosed. Knowing isolated microorganisms and their susceptibility to antibiotics is of importance in terms of directing empiric treatments, enabling doctors to be conscious of controlled and rational usage of antibiotics, and preventing the increase in resistance rates
Objective: Wound site infection is one of the most common infections caused by hospital. It is an important cause of morbidity and mortality. In our study, distribution rates and antibiotics susceptibility of microorganisms we isolated from infection site samples have been determined, and it has been aimed that they should be a guide to empirical treatment options and should help physicians’ controlled and rational usage of antibiotics.Methods: Distribution rates of a total of 693 bacteria and fungi have been investigated, which were generated from wound patterns in 2010-2015. Results: 52.5% 364 of reproduced microorganisms consisted of Gram negative coccus, 42.8% 297 of Gram negative basil and 4.61% 32 of fungus. For Gram positive bacteria, the most common ones are staphylococcus with 88.1%, while 41.4% of them are observed to be Staphylococci aures. For Gram negative bacteria, Escherischia coli 30.6% and Pseudomonas species 18.2% are observed to be the most common. Yeast fungi constitutes the 4.6% of the reproduced microorganisms. Considering their resistance status, the resistance to methicillin was found to be 35.8 % in S. aureus, 71.1% in CoNS coagulase-negative staphylococci , the highest and the lowest resistance was found in S. aureus to be 81.4% to penicillin and 3.2% to fucidic acid. When the resistance status of Gram negative bacteria was studied, it was found out that the highest resistance was 100% to ampicillin/sulbactam, cefoxitine, cefixime, cefuroxime and cefuroksime axetile in Acinetobacter, 93.7% ampicillin in E. coli, 83.3% to piperacillin in Klebsiella species, and 100% to ampicillin/sulbactam in P. aeruginosa, on the other hand, the lowest resistance was 2.8% to meropenem in E. coli, 14.2% to sefoksitin in Klebsiella species, 19.1% to gentamycin in P. aeruginosa, and no resistance developed to trimethoprim/sulfamethoxazole and tetracycline in Acinetobacter species. Conclusion: In this study, the distribution antibiotic susceptibility of microorganisms most frequently causing wound infections were determined in our hospital, the data were compared and contrasted to those of the studies made in our country and abroad, and similarities and differences were disclosed. Knowing isolated microorganisms and their susceptibility to antibiotics is of importance in terms of directing empiric treatments, enabling doctors to be conscious of controlled and rational usage of antibiotics, and preventing the increase in resistance rates
Primary Language | English |
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Journal Section | Research Article |
Authors | |
Publication Date | June 1, 2018 |
Published in Issue | Year 2018 Volume: 75 Issue: 2 |