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Normal values of biochemical parameters in serum of New Zealand White Rabbits

Year 2019, Volume: 76 Issue: 2, 157 - 162, 01.06.2019

Abstract

Objective: Laboratory animals, which are an organ complex, are used as model for human in biomedical studies. For this reason, information about the normal physiological values of laboratory animals provide important information on their health status. In this study, it is aimed to determine the serum normal biochemical values of New Zealand rabbits.Methods: Blood was taken from the ears of 93 rabbits. Biochemical tests were performed on serum samples. For analyses, commercial diagnostic kits were used for determination of biochemical parameters. Statistically, the difference between the mean values of the variables according to male and female rabbit was analyzed by independent sample t-test.Results: Albumin, protein, CK creatin kinase and LDH lactade dehydrogenase p

References

  • Yanni AE. The laboratory rabbit: an animal model of atherosclerosis research. Lab Anim, 2004; 38(3): 246-56.
  • Calasans-Maia MD, Monteiro ML, Ascoli FO, Granjeiro JM. The rabbit as an animal model for experimental surgery. Acta Cir Bras, 2009; 24(4): 325-8.
  • Wang W, Xu R, Li J. Production of Native Bispecific Antibodies in Rabbits. PLoS ONE, 2010; 5(6):e10879. doi:10.1371/journal.pone.001087.
  • Matsuzawa T, Nomura M, Unno T. Clinical pathology reference ranges of laboratory animals. J Vet Med Sci, 1993; 55: 351-62.
  • Mohri M, Sharifi K, Eidi S. Hematology and serum biochemistry of Holstein dairy calves: age related changes and comparison with blood composition in adults. Res Vet Sci, 2007; 83: 30-39.
  • Olayemi FO, Nottidge HO. Effect of age on the blood profiles of the New Zealand White rabbit in Nigeria. Afr J Biomed Res, 2007; 10: 73-76.
  • Mizoguchi Y, Matsuoka T, Mizuguchi H, Endoh T, Kamata R, Fukuda K, Ishikawa T, Asano Y. Changes in blood parameters in New Zealand White rabbits during pregnancy. Lab Anim, 2010; 44(1): 33-9. doi: 10.1258/la.2009.008002.
  • Valdez-Garcia JE, Lozano-Ramirez JF, Zavala J. Adult white New Zealand rabbitas suitable model for corneal endothelial engineering. BMC Res Notes, 2015; 4(8): 28. doi: 10.1186/s13104-015-0995-1.
  • Melillo A. Rabbit Clinical Pathology. Journal of Exotic Pet Medicine, 2007; 16(3): 135-145.
  • Fuentes GC, Newgren J. Physiology and clinical pathology of laboratory New Zealand White rabbits housed individually and in groups. J Am Assoc Lab Anim Sci, 2008; 47(2): 35-38.
  • Özkan C, Kaya A, Akgül Y. Normal values of haematological and some biochemical parametersin serum and urine of New Zealand White rabbits. World Rabbit Sci, 2012; 20: 253-259, <https://doi. org/10.4995/wrs.2012.1229.
  • Sabah AH, Abd Al-Rahman, Dalal Abd Al-Sattar Asaad Baqey. Effect of the thermal changes onphysiological, biochemical and histological traits in pregnantand embryo of New Zealand White rabbits. Int J Adv Biol Res, 2016; 6(2): 313-327.
  • Okab AB, El-Banna SG, Koriem AA. Influence of
  • environmental temperatures on some physiological and biochemical parameters of New-Zealand rabbit males. Slovak J Anim Sci, 2008; 41(1): 12 – 19.
  • Yazar E, Çöl R, Konyalıoğlu S, Birdane YO, Elmas M, Baş AL. Effects of vitamin E and prednisolone on biochemical and haematological parameters in endotoxaemic New Zealand White Rabbits. B Vet I Pulawy, 2004; 48: 105-108.
  • Saad MS, Mohamed AM, Khalid H. Some haemato biochemical values in White New Zealand rabbits. J Agric Vet Sci, 2017; 10(7): 40-44 DOI: 10.9790/2380-1007014044.
  • Seyidoğlu N, Galip N, Sonat FA. Effect of yeast culture on growth performance, haematological and biochemical indices of New Zealand white rabbits. Uludag Univ J Fac Vet Med, 32(2): 11-17, 2013. 24.
  • Dontas IA, Marinou KA, Iliopoulos D, Tsantila N, Agrogiannis G, Papalois A, Karatzas T. Changes of blood biochemistry in the rabbit animal model in atherosclerosis research; a time- or stress- effect. Lipids Health Dis, 2011; 14(10): 139. doi: 10.1186/1476-511X-10-139.
  • Lebas CF, Coudert P, Rouvier R, Rochambeau H. The Rabbit Husbandry, Health and Production. The Food and Agricultureal Organisation of the United Nations, Rome. Çeviri: Vatansever, H. Ankara: Kardelen Ofset. 2002.
  • Manning P, Ringler DH, Newcomer C. The biology of the laboratory rabbit. Academic Press, 1994:111- 344.
  • Caisey JD, King DJ. Clinical chemical values for some common laboratory animals. Clin Chem, 1980; 26: 1877-1879.
  • Loeb W. Clinical Biochemistry of Laboratory Rodents and Rabbits. In: Kaneko JJ, Harvey JW, Bruss ML (eds.). Clinical biochemistry of domestic animals. California: Academic Press. 1997: 845-855.
  • Gil AG, Silvan G, Illera M, Illera JC. The effects of anesthesia on the clinical chemistry of New Zealand White rabbits. Contemp Top, 2004; 43(3): 25-29.

Yeni Zelanda Beyaz Tavşanların Serum Biyokimyasal Parametrelerin Normal Değerleri

Year 2019, Volume: 76 Issue: 2, 157 - 162, 01.06.2019

Abstract

Amaç: Bir organ kompleksi olan laboratuvar hayvanları biyomedikal çalışmalarda insanlar için model olarak kullanılmaktadır. Bu nedenle, laboratuvar hayvanlarının normal fizyolojik değerleri, sağlık durumlarıyla ilgili önemli bilgiler sağlar. Bu çalışmada da Yeni Zelanda tavşanlarının serum normal biyokimyasal değerlerinin belirlenmesi amaçlanmıştır.Yöntem: Toplam 93 60♂; 33♀ tavşanın kulaklarından biyokimyasal testler yapıldı. Analizler için biyokimyasal parametrelerin belirlenmesinde ticari teşhis kitleri kullanıldı. İstatistiksel olarak, erkek ve dişi tavşana göre değişkenlerin ortalama değerleri arasındaki fark bağımsız sample t-testi ile analiz edildi. Bulgular: Erkek tavşanların albümin, protein, CK keratin kinaz ve LDH laktat dehidrogenaz p

References

  • Yanni AE. The laboratory rabbit: an animal model of atherosclerosis research. Lab Anim, 2004; 38(3): 246-56.
  • Calasans-Maia MD, Monteiro ML, Ascoli FO, Granjeiro JM. The rabbit as an animal model for experimental surgery. Acta Cir Bras, 2009; 24(4): 325-8.
  • Wang W, Xu R, Li J. Production of Native Bispecific Antibodies in Rabbits. PLoS ONE, 2010; 5(6):e10879. doi:10.1371/journal.pone.001087.
  • Matsuzawa T, Nomura M, Unno T. Clinical pathology reference ranges of laboratory animals. J Vet Med Sci, 1993; 55: 351-62.
  • Mohri M, Sharifi K, Eidi S. Hematology and serum biochemistry of Holstein dairy calves: age related changes and comparison with blood composition in adults. Res Vet Sci, 2007; 83: 30-39.
  • Olayemi FO, Nottidge HO. Effect of age on the blood profiles of the New Zealand White rabbit in Nigeria. Afr J Biomed Res, 2007; 10: 73-76.
  • Mizoguchi Y, Matsuoka T, Mizuguchi H, Endoh T, Kamata R, Fukuda K, Ishikawa T, Asano Y. Changes in blood parameters in New Zealand White rabbits during pregnancy. Lab Anim, 2010; 44(1): 33-9. doi: 10.1258/la.2009.008002.
  • Valdez-Garcia JE, Lozano-Ramirez JF, Zavala J. Adult white New Zealand rabbitas suitable model for corneal endothelial engineering. BMC Res Notes, 2015; 4(8): 28. doi: 10.1186/s13104-015-0995-1.
  • Melillo A. Rabbit Clinical Pathology. Journal of Exotic Pet Medicine, 2007; 16(3): 135-145.
  • Fuentes GC, Newgren J. Physiology and clinical pathology of laboratory New Zealand White rabbits housed individually and in groups. J Am Assoc Lab Anim Sci, 2008; 47(2): 35-38.
  • Özkan C, Kaya A, Akgül Y. Normal values of haematological and some biochemical parametersin serum and urine of New Zealand White rabbits. World Rabbit Sci, 2012; 20: 253-259, <https://doi. org/10.4995/wrs.2012.1229.
  • Sabah AH, Abd Al-Rahman, Dalal Abd Al-Sattar Asaad Baqey. Effect of the thermal changes onphysiological, biochemical and histological traits in pregnantand embryo of New Zealand White rabbits. Int J Adv Biol Res, 2016; 6(2): 313-327.
  • Okab AB, El-Banna SG, Koriem AA. Influence of
  • environmental temperatures on some physiological and biochemical parameters of New-Zealand rabbit males. Slovak J Anim Sci, 2008; 41(1): 12 – 19.
  • Yazar E, Çöl R, Konyalıoğlu S, Birdane YO, Elmas M, Baş AL. Effects of vitamin E and prednisolone on biochemical and haematological parameters in endotoxaemic New Zealand White Rabbits. B Vet I Pulawy, 2004; 48: 105-108.
  • Saad MS, Mohamed AM, Khalid H. Some haemato biochemical values in White New Zealand rabbits. J Agric Vet Sci, 2017; 10(7): 40-44 DOI: 10.9790/2380-1007014044.
  • Seyidoğlu N, Galip N, Sonat FA. Effect of yeast culture on growth performance, haematological and biochemical indices of New Zealand white rabbits. Uludag Univ J Fac Vet Med, 32(2): 11-17, 2013. 24.
  • Dontas IA, Marinou KA, Iliopoulos D, Tsantila N, Agrogiannis G, Papalois A, Karatzas T. Changes of blood biochemistry in the rabbit animal model in atherosclerosis research; a time- or stress- effect. Lipids Health Dis, 2011; 14(10): 139. doi: 10.1186/1476-511X-10-139.
  • Lebas CF, Coudert P, Rouvier R, Rochambeau H. The Rabbit Husbandry, Health and Production. The Food and Agricultureal Organisation of the United Nations, Rome. Çeviri: Vatansever, H. Ankara: Kardelen Ofset. 2002.
  • Manning P, Ringler DH, Newcomer C. The biology of the laboratory rabbit. Academic Press, 1994:111- 344.
  • Caisey JD, King DJ. Clinical chemical values for some common laboratory animals. Clin Chem, 1980; 26: 1877-1879.
  • Loeb W. Clinical Biochemistry of Laboratory Rodents and Rabbits. In: Kaneko JJ, Harvey JW, Bruss ML (eds.). Clinical biochemistry of domestic animals. California: Academic Press. 1997: 845-855.
  • Gil AG, Silvan G, Illera M, Illera JC. The effects of anesthesia on the clinical chemistry of New Zealand White rabbits. Contemp Top, 2004; 43(3): 25-29.
There are 23 citations in total.

Details

Primary Language English
Journal Section Research Article
Authors

Özcan Özkan This is me

Selcuk Pekkaya This is me

Publication Date June 1, 2019
Published in Issue Year 2019 Volume: 76 Issue: 2

Cite

APA Özkan, Ö., & Pekkaya, S. (2019). Normal values of biochemical parameters in serum of New Zealand White Rabbits. Türk Hijyen Ve Deneysel Biyoloji Dergisi, 76(2), 157-162.
AMA Özkan Ö, Pekkaya S. Normal values of biochemical parameters in serum of New Zealand White Rabbits. Turk Hij Den Biyol Derg. June 2019;76(2):157-162.
Chicago Özkan, Özcan, and Selcuk Pekkaya. “Normal Values of Biochemical Parameters in Serum of New Zealand White Rabbits”. Türk Hijyen Ve Deneysel Biyoloji Dergisi 76, no. 2 (June 2019): 157-62.
EndNote Özkan Ö, Pekkaya S (June 1, 2019) Normal values of biochemical parameters in serum of New Zealand White Rabbits. Türk Hijyen ve Deneysel Biyoloji Dergisi 76 2 157–162.
IEEE Ö. Özkan and S. Pekkaya, “Normal values of biochemical parameters in serum of New Zealand White Rabbits”, Turk Hij Den Biyol Derg, vol. 76, no. 2, pp. 157–162, 2019.
ISNAD Özkan, Özcan - Pekkaya, Selcuk. “Normal Values of Biochemical Parameters in Serum of New Zealand White Rabbits”. Türk Hijyen ve Deneysel Biyoloji Dergisi 76/2 (June 2019), 157-162.
JAMA Özkan Ö, Pekkaya S. Normal values of biochemical parameters in serum of New Zealand White Rabbits. Turk Hij Den Biyol Derg. 2019;76:157–162.
MLA Özkan, Özcan and Selcuk Pekkaya. “Normal Values of Biochemical Parameters in Serum of New Zealand White Rabbits”. Türk Hijyen Ve Deneysel Biyoloji Dergisi, vol. 76, no. 2, 2019, pp. 157-62.
Vancouver Özkan Ö, Pekkaya S. Normal values of biochemical parameters in serum of New Zealand White Rabbits. Turk Hij Den Biyol Derg. 2019;76(2):157-62.